Zobrazeno 1 - 10
of 895
pro vyhledávání: '"Kaiming Zhang"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract MuB is a non-specific DNA-binding protein and AAA+ ATPase that significantly influences the DNA transposition process of bacteriophage Mu, especially in target DNA selection for transposition. While studies have established the ATP-dependent
Externí odkaz:
https://doaj.org/article/1e28b0800c3c48a3867ff60d193d2508
Autor:
Pengfei Fan, Mengmeng Sun, Xinghai Zhang, Huajun Zhang, Yujiao Liu, Yanfeng Yao, Ming Li, Ting Fang, Bingjie Sun, Zhengshan Chen, Xiangyang Chi, Li Chen, Cheng Peng, Zhen Chen, Guanying Zhang, Yi Ren, Zixuan Liu, Yaohui Li, Jianmin Li, Entao Li, Wuxiang Guan, Shanshan Li, Rui Gong, Kaiming Zhang, Changming Yu, Sandra Chiu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The Hendra and Nipah viruses (HNVs) are highly pathogenic pathogens without approved interventions for human use. In addition, the interaction pattern between the attachment (G) and fusion (F) glycoproteins required for virus entry remains u
Externí odkaz:
https://doaj.org/article/14e8c25791854095a7cb85b5e6910684
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
The differentiation of vascular endothelial cells and the formation of new blood vessels are inseparable from the energy supply and regulation of metabolism. The budding of blood vessels is a starting point of glycolysis pathway in angiogenesis. Phos
Externí odkaz:
https://doaj.org/article/a1f5bec94b96434faf2dcaf8558fabea
Autor:
Xinyan Chen, Anat Raiff, Shanshan Li, Qiong Guo, Jiahai Zhang, Hualin Zhou, Richard T. Timms, Xuebiao Yao, Stephen J. Elledge, Itay Koren, Kaiming Zhang, Chao Xu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The E3 ligase-degron interaction determines the specificity of the ubiquitin‒proteasome system. We recently discovered that FEM1B, a substrate receptor of Cullin 2-RING ligase (CRL2), recognizes C-degrons containing a C-terminal proline. B
Externí odkaz:
https://doaj.org/article/ffbc3ea809874fc5b76a3798f02b99ec
Autor:
Li Chen, Mengmeng Sun, Huajun Zhang, Xinghai Zhang, Yanfeng Yao, Ming Li, Kangyin Li, Pengfei Fan, Haiwei Zhang, Ye Qin, Zhe Zhang, Entao Li, Zhen Chen, Wuxiang Guan, Shanshan Li, Changming Yu, Kaiming Zhang, Rui Gong, Sandra Chiu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Nipah virus (NiV) is a World Health Organization priority pathogen and there are currently no approved drugs for clinical immunotherapy. Through the use of a naïve human phage-displayed Fab library, two neutralizing antibodies (NiV41 and Ni
Externí odkaz:
https://doaj.org/article/8960ea1cd51c4e3a95f8fabca3b7e65c
Autor:
Hailei Zhang, Bo Zhang, Chongyang Cai, Kaiming Zhang, Yu Wang, Yuan Wang, Yanmin Yang, Yonggang Wu, Xinwu Ba, Richard Hoogenboom
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Developing X-ray scintillators that are water-dispersible, compatible with polymeric matrices, and processable to flexible substrates is an important challenge. Herein, Tb3+-doped Na5Lu9F32 is introduced as an X-ray scintillating material wi
Externí odkaz:
https://doaj.org/article/80954e4743ea474da034677682e16d71
Publikováno v:
Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
Background: Psoriasis is a prevalent skin disease affecting approximately 1%–3% of the population and imposes significant medical, social and economic burdens. Psoriasis involves multiple organs and is often complicated with obesity, diabetes, dysl
Externí odkaz:
https://doaj.org/article/48f2bbd92bea478993d2d6bf124217ae
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Actin remodeling proteins are important in immune diseases and regulate cell cytoskeletal responses. These responses play a pivotal role in maintaining the delicate balance of biological events, protecting against acute or chronic inflammation in a r
Externí odkaz:
https://doaj.org/article/5930a8e797884bf3baac99f24a68d170
Autor:
Qingshan Chen, Fenglin Gao, Junwan Wu, Kaiming Zhang, Tian Du, Yuhong Chen, Ruizhao Cai, Dechang Zhao, Rong Deng, Jun Tang
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 6, Pp n/a-n/a (2024)
Abstract Background Mitochondrial outer membrane permeabilisation (MOMP) plays a pivotal role in cellular death and immune activation. A deeper understanding of the impact of tumour MOMP on immunity will aid in guiding more effective immunotherapeuti
Externí odkaz:
https://doaj.org/article/43ecb89d02374b6f822f97327af205c5
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Histamine receptors are a group of G protein-coupled receptors (GPCRs) that play important roles in various physiological and pathophysiological conditions. Antihistamines that target the histamine H1 receptor (H1R) have been widely used to
Externí odkaz:
https://doaj.org/article/f965e3627ca64750b595e5c24d924fd6