Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kaimeng Zhou"'
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 185:177-182
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::876b2ba40697deb89f7eb4639ab3f87e
https://doi.org/10.1016/j.ejpb.2023.03.001
https://doi.org/10.1016/j.ejpb.2023.03.001
Autor:
Tapan K. Das, Zhi Chen, Duohai Pan, Kaimeng Zhou, Gurusamy Balakrishnan, Ming Zeng, Sung-Joo Park
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 183
Monoclonal antibodies are heterogeneous in nature and may contain numerous variants with differences in size, charge, and hydrophobicity, which may impact clinical efficacy, immunogenicity, and safety. Characterization of antibody variants is necessa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78539b52bb60dfd5a807ce5fc5e9742e
https://pubmed.ncbi.nlm.nih.gov/32086124
https://pubmed.ncbi.nlm.nih.gov/32086124
Autor:
Tapan K. Das, Zhi Chen, Neil Hershey, Ming Zeng, Li Tao, James Bautista, Richard Ludwig, Xiang Cao, Kaimeng Zhou
Publikováno v:
Journal of pharmaceutical sciences. 109(1)
Isomerization of surface-exposed aspartic acid (Asp) in the complementarity-determining regions of therapeutic proteins could potentially impact their target binding affinity because of the sensitive location, and often requires complex analytical ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7247867ac649d597c0777e7c46a47e7
https://pubmed.ncbi.nlm.nih.gov/31469998
https://pubmed.ncbi.nlm.nih.gov/31469998
Publikováno v:
Annual Review of Analytical Chemistry. 4:321-341
Ion transport and sensing in nanofluidic devices are receiving a great deal of attention because of their unique transport properties and potential analytical applications. Some aspects of microscale transport transfer directly to the nanoscale, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e98f5ced4a821841424a573f8938da
https://doi.org/10.1146/annurev-anchem-061010-113938
https://doi.org/10.1146/annurev-anchem-061010-113938
Publikováno v:
Journal of the American Chemical Society. 133:1618-1621
We report characterization of hepatitis B virus (HBV) capsids by resistive-pulse sensing through single track-etched conical nanopores formed in poly(ethylene terephthalate) membranes. The pores were ∼40 nm in diameter at the tip, and the pore surf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922eecc4790f375a02acdc0049a9a4a8
https://doi.org/10.1021/ja108228x
https://doi.org/10.1021/ja108228x
Publikováno v:
ACS Nano. 4:3897-3902
We report fabrication of nanofluidic channels with asymmetric features (e.g., funnels) that were cast in high modulus poly(dimethylsiloxane) and had well-defined geometries and dimensions. Masters used to cast the funnels were written in the negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f64e27064b661f3bef2b49e78292994
https://doi.org/10.1021/nn100692z
https://doi.org/10.1021/nn100692z
Autor:
Indranil Mitra, Klaus Bo Mogensen, Stephen C. Jacobson, Brett W. Hildenbrand, Jörg Peter Kutter, Zhenning Tan, Kaimeng Zhou, P. Nunes, Zachary D. Harms, Adam Zlotnick
Publikováno v:
Analytical chemistry. 83(24)
We report fabrication and characterization of nanochannel devices with two nanopores in series for resistive-pulse sensing of hepatitis B virus (HBV) capsids. The nanochannel and two pores are patterned by electron beam lithography between two microc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff22ceed59bd77cb54117afe93c48d3
https://pubmed.ncbi.nlm.nih.gov/22029283
https://pubmed.ncbi.nlm.nih.gov/22029283
Publikováno v:
The journal of physical chemistry. B. 113(49)
Asymmetric nanoscale conduits, such as conical track-etch pores, rectify ion current due to surface charge effects. To date, most data concerning this phenomenon have been obtained for small nanopores with diameters comparable to the electrical doubl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33a3538ca40f040b24bf1be5081d273
https://pubmed.ncbi.nlm.nih.gov/19908894
https://pubmed.ncbi.nlm.nih.gov/19908894
Publikováno v:
Frontiers in Optics 2009/Laser Science XXV/Fall 2009 OSA Optics & Photonics Technical Digest.
Nanofluidic channels integrated into microfluidic devices offer a unique platform for studying ion transport behavior. We present a method to fabricate these integrated devices in-plane, which permits simultaneous optical and electrical characterizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a333e08feba62b113e325fe2467a32cf
https://doi.org/10.1364/ls.2009.lsmg5
https://doi.org/10.1364/ls.2009.lsmg5
Publikováno v:
Journal of the American Chemical Society. 130(27)
We report integrated nanopore/microchannel devices in which single nanopores are isolated between two microfluidic channels. The devices were formed by sandwiching track-etched conical nanopores in a poly(ethylene terephthalate) membrane between two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db37b9db7beeb9bf8cd247a28152ae9
https://pubmed.ncbi.nlm.nih.gov/18549214
https://pubmed.ncbi.nlm.nih.gov/18549214