Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kailo H. Schlegel"'
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Natural IgM anti-leukocyte autoantibodies (IgM-ALAs) inhibit inflammation by several mechanisms. Here, we show that pan-B cells and bone marrow-derived dendritic cells (BMDCs) are switched to regulatory cells when pretreated ex vivo with IgM. B cells
Externí odkaz:
https://doaj.org/article/0c3818918fce4e6a85ea7f7fbcd2caf3
Autor:
Canan Kuscu, Amandeep Bajwa, Daniel Maluf, Thomas V. Rousselle, Maria Namwanje, James D. Eason, Cem Kuscu, Kailo H. Schlegel, Liza Makowski, Liping Huang, V. Mas
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
Dendritic cells (DCs) are central in regulating immune responses of kidney ischemia-reperfusion injury (IRI), and strategies to alter DC function may provide new therapeutic opportunities. Sphingosine 1-phosphate (S1P) modulates immunity through bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504a3ec371a7c599600895b94e50edf3
http://europepmc.org/articles/PMC7328774
http://europepmc.org/articles/PMC7328774
Autor:
Gilbert R. Kinsey, Peter I. Lobo, Thomas F. Tedder, Amandeep Bajwa, Hong Ye, Liping Huang, Mark D. Okusa, Binru Wang, Kailo H. Schlegel, Elvira Kurmaeva
Publikováno v:
The Journal of Immunology. 195:5215-5226
We have previously shown that polyclonal natural IgM protects mice from renal ischemia/reperfusion injury (IRI) by inhibiting the reperfusion inflammatory response. We hypothesized that a potential mechanism involved IgM modulation of dendritic cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55187ec2aa309b806c57f9ab1033094c
https://doi.org/10.4049/jimmunol.1500052
https://doi.org/10.4049/jimmunol.1500052
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Frontiers in Immunology
Natural IgM anti-leukocyte autoantibodies (IgM-ALAs) inhibit inflammation by several mechanisms. Here, we show that pan-B cells and bone marrow-derived dendritic cells (BMDCs) are switched to regulatory cells when pretreated ex vivo with IgM. B cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7698d809fca5bb81ad8057c831dd0540
Autor:
Umesh S. Deshmukh, Amandeep Bajwa, Hong Ye, John Vengal, Tong Wang, Peter I. Lobo, Kailo H. Schlegel, Sang J. Lee, Liping Huang, Hong Pei, Mark D. Okusa
Publikováno v:
The Journal of Immunology. 188:1675-1685
Little is known about the function of natural IgM autoantibodies, especially that of IgM anti-leukocyte autoantibodies (IgM-ALA). Natural IgM-ALA are present at birth and characteristically increase during inflammatory and infective conditions. Our p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a44b2f63fb8b9fee9d71b9284577dba
https://doi.org/10.4049/jimmunol.1101762
https://doi.org/10.4049/jimmunol.1101762
Autor:
Mark D. Okusa, Clinton E. Spencer, Nino Mchedlishvili, Andrew J. Park, Constance Christ, Christopher Burtner, Christopher Chisholm, Peter I. Lobo, Kailo H. Schlegel
Publikováno v:
The Journal of Immunology. 180:1780-1791
The physiological relevance of naturally occurring IgM-ALA remains to be elucidated. These autoantibodies are present from birth and increase in diverse inflammatory states that are both infectious and noninfectious. Clinical observations showing sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ea564eab53e40210c74929962cdd75
https://doi.org/10.4049/jimmunol.180.3.1780
https://doi.org/10.4049/jimmunol.180.3.1780
Publikováno v:
Annals of surgery. 256(4)
Autoimmune type 1 diabetes mellitus (T1D) is a multifactorial disease caused by the progressive destruction of insulin-producing pancreatic β-cells that results in an absolute loss of insulin production.1,2 Prevention or reversal of T1D either by pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db26949ab3d65edc9ee9f7f7e822461
https://pubmed.ncbi.nlm.nih.gov/22964733
https://pubmed.ncbi.nlm.nih.gov/22964733
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 180(3)
In prior studies, we show that naturally occurring IgM anti-leukocyte autoantibodies (IgM-ALA) bind to CD3, CD4, CCR5, and CXCR4 receptors. These observations prompted us to determine whether IgM-ALA have a role in inhibiting HIV-1 infectivity by inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdf4f851668952fea66139873dffd9f
https://pubmed.ncbi.nlm.nih.gov/18209074
https://pubmed.ncbi.nlm.nih.gov/18209074
Autor:
Kailo H. Schlegel, Tom G. Obrig, Peter I. Lobo, Randal E. Morris, Takashi Matsui, Georgianne M. Ciraolo, Takashi Yutsudo, Daniel P. Heatherly, Jun Fujii
Publikováno v:
Infection and immunity. 71(5)
Apoptosis was induced rapidly in HeLa cells after exposure to bacterial Shiga toxin (Stx1 and Stx2; 10 ng/ml). Approximately 60% of HeLa cells became apoptotic within 4 h as detected by DNA fragmentation, terminal deoxynucleotidyltransferase-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b042130cf9ab58d9b3ebe71e994ccd97
https://pubmed.ncbi.nlm.nih.gov/12704147
https://pubmed.ncbi.nlm.nih.gov/12704147
Autor:
Kailo H. Schlegel, Peter I. Lobo
Publikováno v:
Transplantation. 78:523-524
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc5fc329fc4fa4019d693695a16b4c64
https://doi.org/10.1097/00007890-200407271-01412
https://doi.org/10.1097/00007890-200407271-01412