Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kailing Fu"'
Autor:
Norman E. Sharpless, Sharon L. Campbell, Bruce C. Baguley, Michael J. Miley, Daniel C. Zedek, David B. Darr, George P. Souroullas, William R. Jeck, Brit L. Martin, Kailing Fu, Kelly S. Clark, James E. Gillahan, Meriam A. Waqas, Minh V. Huynh, Wenjin Liu, Christin E. Burd
Figure S1. Generation of the LSL-N-RasQ61R allele. Figure S2. Conditional expression of N-Ras mutants does not alter melanocyte morphology. Figure S3. In both the heterozygous and homozygous state, NRasG12D fails to induce melanoma formation. Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5c3e3adfbf56270fa607f7d8df27f8
https://doi.org/10.1158/2159-8290.22530242.v1
https://doi.org/10.1158/2159-8290.22530242.v1
Autor:
Norman E. Sharpless, Sharon L. Campbell, Bruce C. Baguley, Michael J. Miley, Daniel C. Zedek, David B. Darr, George P. Souroullas, William R. Jeck, Brit L. Martin, Kailing Fu, Kelly S. Clark, James E. Gillahan, Meriam A. Waqas, Minh V. Huynh, Wenjin Liu, Christin E. Burd
NRAS mutation at codons 12, 13, or 61 is associated with transformation; yet, in melanoma, such alterations are nearly exclusive to codon 61. Here, we compared the melanoma susceptibility of an NrasQ61R knock-in allele to similarly designed KrasG12D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b07545ea77a4bfaa05fa90bb50b2e69
https://doi.org/10.1158/2159-8290.c.6546137.v1
https://doi.org/10.1158/2159-8290.c.6546137.v1
Autor:
Christin E. Burd, Michael J. Miley, Wenjin Liu, Bruce C. Baguley, David B. Darr, Norman E. Sharpless, Meriam A. Waqas, Brit L. Martin, Kailing Fu, William R. Jeck, Kelly S. Clark, George P. Souroullas, Daniel C. Zedek, Minh V. Huynh, Sharon L. Campbell, James E. Gillahan
Publikováno v:
Cancer Discovery. 4:1418-1429
NRAS mutation at codons 12, 13, or 61 is associated with transformation; yet, in melanoma, such alterations are nearly exclusive to codon 61. Here, we compared the melanoma susceptibility of an NrasQ61R knock-in allele to similarly designed KrasG12D
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 14(2)
Lentiviral vector safety has been the impetus underlying the progress in packaging cell line development. The prospects of generating replication-competent lentiviruses (RCLs) and the potential for vector mobilization continue to be the driving force
Autor:
William R. Jeck, Kelly S. Clark, Jessie Xiong, Kailing Fu, George P. Souroullas, Christin E. Burd, Norman E. Sharpless
Publikováno v:
Cancer Research. 73:1087-1087
In human cancer, N-RAS mutations resulting in constitutive, oncogenic signaling are predominately localized to codons 12, 13 or 61. Traditionally, activating RAS mutations have been considered oncogenically equivalent, yet recent studies suggest impo
Publikováno v:
Molecular Therapy. 9:S28
Top of pageAbstract The traditional method for producing self-inactivating lentiviral stocks has been the three/four plasmid transient transfection method. However, employing packaging cell lines to produce lentiviral vector stocks may circumvent inc