Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Kailiang Zhao"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/9267aed530374e9a90aa48b42b1afad7
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Objective Numerous epidemiological investigations have explored the impact of body composition on the effectiveness of immune checkpoint inhibitors (ICIs) in urological malignancies (UM) patients, yielding conflicting findings. As a result,
Externí odkaz:
https://doaj.org/article/91235abc3ce14987bccfff7cf33723d4
Autor:
Jie Shen, Dashuai Yang, Yu Zhou, Junpeng Pei, Zhongkai Wu, Xin Wang, Kailiang Zhao, Youming Ding
Publikováno v:
BMC Geriatrics, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Intrahepatic cholangiocarcinoma (ICC) has a poor prognosis and is understudied. Based on the clinical features of patients with ICC, we constructed machine learning models to understand their importance on survival and to accurate
Externí odkaz:
https://doaj.org/article/07538d21ea2c42f9a7858ff8c9b71cc7
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundMost patients with multiple hepatocellular carcinoma (MHCC) are at advanced stage once diagnosed, so that clinical treatment and decision-making are quite tricky. The AJCC-TNM system cannot accurately determine prognosis, our study aimed to
Externí odkaz:
https://doaj.org/article/657d2eb4ca47452d9af42f6fcc8ed183
Autor:
Rongqiang Liu, Zhendong Qiu, Lilong Zhang, Wangbin Ma, Liuliu Zi, Kunpeng Wang, Tainrui Kuang, Kailiang Zhao, Weixing Wang
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 6, Pp 2509-2519 (2023)
Abstract Sarcopenia has been considered an adverse prognostic factor in cancer patients. Intramuscular adipose tissue content, as a new marker of sarcopenia, can effectively reflect skeletal muscle quality. The aim of this study was performed to eval
Externí odkaz:
https://doaj.org/article/84f07040d8d245e785d7b3b3be94909f
Autor:
Xinrui Lin, Guofeng Zhu, Dongdong Qiu, Linlin Ye, Yuwei Liu, Yinying Jiao, Lei Wang, Kailiang Zhao, Wenhao Zhang, Jiawei Liu, Qinqin Wang
Publikováno v:
Journal of Hydrology: Regional Studies, Vol 51, Iss , Pp 101633- (2024)
Study region: The Xiying River Basin is a typical inland mountainous watershed located in the Qilian Mountains. Study focus: This article reveals the change of runoff stable isotopes and their control mechanisms based on isotope data of different wat
Externí odkaz:
https://doaj.org/article/55ea983f49554f358e0190df29c55717
Autor:
Debao Fang, Hao Hu, Kailiang Zhao, Aman Xu, Changjun Yu, Yong Zhu, Ning Yu, Bo Yao, Suyun Tang, Xianning Wu, Yide Mei
Publikováno v:
Advanced Science, Vol 10, Iss 26, Pp n/a-n/a (2023)
Abstract Inactivation of the p53 pathway is linked to a variety of human cancers. As a critical component of the p53 pathway, ubiquitin‐specific protease 7 (USP7) acts as a deubiquitinase for both p53 and its ubiquitin E3 ligase mouse double minute
Externí odkaz:
https://doaj.org/article/b7701baaa11b471394c969ff6a562443
Autor:
Lilong Zhang, Kailiang Zhao, Tianrui kuang, Kunpeng Wang, Dongqi Chai, Zhendong Qiu, Rongqiang Liu, Wenhong Deng, Weixing Wang
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Systemic inflammation is crucial for the development and progression of cancers. The advanced lung cancer inflammation index (ALI) is considered to be a better indicator of systemic inflammation than current biomarkers. However, t
Externí odkaz:
https://doaj.org/article/37e21f8c570741ba8bc7d635b5e09ddf
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Background: M2 macrophages perform an influential role in the progression of pancreatic cancer. This study is dedicated to explore the value of M2 macrophage-related genes in the treatment and prognosis of pancreatic cancer.Methods: RNA-Seq and clini
Externí odkaz:
https://doaj.org/article/f1b5f441cae34a259e701433f7573524
Autor:
Hao Hu, Kailiang Zhao, Debao Fang, Zhongyu Wang, Ning Yu, Bo Yao, Kaiyue Liu, Fang Wang, Yide Mei
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112288- (2023)
Summary: The tumor suppressor p53 plays a pivotal role in tumor prevention. The activity of p53 is mainly restrained by the ubiquitin E3 ligase Mdm2. However, it is not well understood how the Mdm2-p53 pathway is intricately regulated. Here we report
Externí odkaz:
https://doaj.org/article/09d0eab6ad8d401392fc0738edd6346f