Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kailiang, Sun"'
Publikováno v:
Dev Biol
microRNAs (miRNAs) are ~21–22 nucleotide (nt) RNAs that mediate broad post-transcriptional regulatory networks. However, genetic analyses have shown that the phenotypic consequences of deleting individual miRNAs are generally far less overt compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba51e8f7575e2369d5f0f3f6a856cff
https://doi.org/10.1016/j.ydbio.2021.02.010
https://doi.org/10.1016/j.ydbio.2021.02.010
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005245 (2015)
While most miRNA knockouts exhibit only subtle defects, a handful of miRNAs are profoundly required for development or physiology. A particularly compelling locus is Drosophila mir-279, which was reported as essential to restrict the emergence of CO2
Externí odkaz:
https://doaj.org/article/f8c60f76672c427e9f66673e986a35be
Autor:
Kailiang Sun, Jakub Orzechowski Westholm, Kazuya Tsurudome, Joshua W Hagen, Yubing Lu, Minoree Kohwi, Doron Betel, Fen-Biao Gao, A Pejmun Haghighi, Chris Q Doe, Eric C Lai
Publikováno v:
PLoS Genetics, Vol 8, Iss 2, p e1002515 (2012)
miR-124 is conserved in sequence and neuronal expression across the animal kingdom and is predicted to have hundreds of mRNA targets. Diverse defects in neural development and function were reported from miR-124 antisense studies in vertebrates, but
Externí odkaz:
https://doaj.org/article/2dc79ea36ad24fe7bab34e6b25d87eba
Autor:
Yannis Emmanuel Mavromatakis, Cyrus Zhou, Kayla Viets, Andrew Tomlinson, Luis F. de Navas, Joshua Kavaler, Robert J. Johnston, Hong Duan, Eric C. Lai, Kailiang Sun, Fuqu Hu
Publikováno v:
Development.
Photoreceptors in the crystalline Drosophila eye are recruited by receptor tyrosine kinase (RTK)/Ras signaling, mediated by the Epidermal Growth Factor receptor (EGFR) and Sevenless receptor. Analyses of an allelic deletion series of the mir-279/996
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5f1e403f23b01c807c0e492b0217bbb
https://doi.org/10.1242/dev.159053
https://doi.org/10.1242/dev.159053
Autor:
Hong, Duan, Luis F, de Navas, Fuqu, Hu, Kailiang, Sun, Yannis E, Mavromatakis, Kayla, Viets, Cyrus, Zhou, Joshua, Kavaler, Robert J, Johnston, Andrew, Tomlinson, Eric C, Lai
Publikováno v:
Development (Cambridge, England). 145(7)
Photoreceptors in the crystalline Drosophila eye are recruited by receptor tyrosine kinase (RTK)/Ras signaling mediated by Epidermal growth factor receptor (EGFR) and the Sevenless (Sev) receptor. Analyses of an allelic deletion series of the mir-279
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf7af5abc7753d50339bfe9f00f36402
https://pubmed.ncbi.nlm.nih.gov/29540498
https://pubmed.ncbi.nlm.nih.gov/29540498
Autor:
Eric C. Lai, Kailiang Sun
Publikováno v:
Nature Reviews Genetics. 14:535-548
microRNAs (miRNAs) are ~22 nucleotide (nt) RNAs that coordinate vast regulatory networks in animals, and thereby influence myriad processes. This review examines evidence that miRNAs play continuous roles in adults, in ways that are separable from de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36432aaaea1843107290b2b19f2f0584
https://doi.org/10.1038/nrg3471
https://doi.org/10.1038/nrg3471
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005245 (2015)
PLoS Genetics
PLoS Genetics
While most miRNA knockouts exhibit only subtle defects, a handful of miRNAs are profoundly required for development or physiology. A particularly compelling locus is Drosophila mir-279, which was reported as essential to restrict the emergence of CO2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814de9494f8633742f37cba72ce2b3b1
http://europepmc.org/articles/PMC4456407?pdf=render
http://europepmc.org/articles/PMC4456407?pdf=render
Autor:
Hong Duan, de Navas, Luis F., Fuqu Hu, Kailiang Sun, Mavromatakis, Yannis E., Viets, Kayla, Zhou, Cyrus, Kavaler, Joshua, Johnston, Robert J., Tomlinson, Andrew, Lai, Eric C.
Publikováno v:
Development (09501991); 4/1/2018, Vol. 145 Issue 7, p1-13, 13p
Autor:
Jr-Shiuan Yang, Qi Dai, Fernando Bejarano, Kevin Kim, Norbert Perrimon, Diane Bortolamiol-Becet, Eric C. Lai, Hong Duan, David R. Raleigh, David Van Vactor, Abil Saj, Tudor A. Fulga, Yu-ting Chou, Kailiang Sun, Jian-Quan Ni
Publikováno v:
Development (Cambridge, England). 139(15)
microRNAs (miRNAs) are endogenous short RNAs that mediate vast networks of post-transcriptional gene regulation. Although computational searches and experimental profiling provide evidence for hundreds of functional targets for individual miRNAs, suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcc3d5954d3ede09c103d5b17f6860b
https://pubmed.ncbi.nlm.nih.gov/22745315
https://pubmed.ncbi.nlm.nih.gov/22745315
Autor:
Yubing Lu, Doron Betel, Joshua W. Hagen, Chris Q. Doe, Jakub Orzechowski Westholm, Minoree Kohwi, A. Pejmun Haghighi, Fen-Biao Gao, Kailiang Sun, Eric C. Lai, Kazuya Tsurudome
Publikováno v:
PLoS Genetics, Vol 8, Iss 2, p e1002515 (2012)
PLoS Genetics
PLoS Genetics
miR-124 is conserved in sequence and neuronal expression across the animal kingdom and is predicted to have hundreds of mRNA targets. Diverse defects in neural development and function were reported from miR-124 antisense studies in vertebrates, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de44a68607fe85a594c51eab5ed6f5f
http://europepmc.org/articles/PMC3276548?pdf=render
http://europepmc.org/articles/PMC3276548?pdf=render