Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Kailash C. Chadha"'
Autor:
B. Bindukumar, Stanley A. Schwartz, Madhavan P.N. Nair, Ravikumar Aalinkeel, Elzbieta Kawinski, Kailash C. Chadha
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 3, Pp 241-252 (2005)
Prostate-specific antigen (PSA) is a serine protease that is widely used as a surrogate marker in the early diagnosis and management of prostate cancer. The physiological relevance of tissue PSA levels and their role in prostate tumor growth and meta
Externí odkaz:
https://doaj.org/article/3a12e87987854dfa8526edc1ca237c41
Autor:
Rebecca Podolsky, Channa Kolb, Joseph F. Quinn, Zohara Sternberg, Adam Nir, Stanley W. Halvorsen, Jihnhee Yu, Jeffrey Kaye, Kailash C. Chadha, Nir Raphael
Publikováno v:
Journal of the neurological sciences. 400
Background/aims Prostate specific antigen (PSA) is regulated by steroid hormones, such as testosterone, the serum levels of which are altered in patients with Alzheimer's disease (AD).This pilot study compared serum levels of the free (f) PSA between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0bfd6e798023aef225e369065787c1
https://pubmed.ncbi.nlm.nih.gov/30981123
https://pubmed.ncbi.nlm.nih.gov/30981123
Autor:
Haotian Sun, Supriya D. Mahajan, Bindukumar Nair, Hanguang Zhang, Jessica L. Reynolds, Donald E. Sykes, Chih-Kuang Chen, Kailash C. Chadha, Katelyn D. Bothwell, Steven G. Turowski, Stanley A. Schwartz, Mukund Seshadri, Chong Cheng, Ravikumar Aalinkeel
Publikováno v:
Immunology. 148:387-406
Interleukin-8 (IL-8) is a pro-angiogenic cytokine associated with aggressive prostate cancer (CaP). We detected high levels of IL-8 in sera from patients with CaP compared with healthy controls and patients with benign prostatic hypertrophy. This stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b786a31707a72a75e391c91267e0e60d
https://doi.org/10.1111/imm.12618
https://doi.org/10.1111/imm.12618
Autor:
Daniel Sternberg, David Hojnacki, Chana Kolb, Trevor Chichelli, Zohara Sternberg, Kailash C. Chadha, Neel Patel, Allison Drake, Jinhee Yu
Publikováno v:
Immunologic Research. 64:385-391
This study is one in series determining the potential of RAGE axis (receptor for advanced glycation end products, isoforms, ligands) as a biomarker in multiple sclerosis (MS). We evaluated serum levels of RAGE ligand, the high-mobility group box (HMG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947f72a56312490d6a55456fa6849f10
https://doi.org/10.1007/s12026-015-8673-x
https://doi.org/10.1007/s12026-015-8673-x
Autor:
Neel Patel, Alejandro Godoy, Gary J. Smith, Rita Zhou, Bindukumar Nair, Stanley A. Schwartz, Rajendram V. Rajnarayanan, Erik Nabi, Kailash C. Chadha, Ravikumar Aalinkeel
Publikováno v:
The Prostate. 75:1285-1299
BACKGROUND PSA is a biomarker for diagnosis and management of prostate cancer. PSA is known to have anti-tumorigenic activities, however, the physiological role of PSA in prostate tumor progression is not well understood. METHODS Five candidate pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc5c651e07422bef5a6d9e7a7aaa650a
https://doi.org/10.1002/pros.23010
https://doi.org/10.1002/pros.23010
Autor:
Fan Li, Daniel Sternberg, Zohara Sternberg, Kailash C. Chadha, Yuval Karmon, Elad I. Levy, Christopher Leung
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 12:104-111
Background: Inflammation is known to play a role in cererovascular risk. Multiple sclerosis (MS) is a neurodegenerative disease that is initially characterized by inflammatory changes in the brain. We hypothesized that due to chronic inflammation, MS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21eb619b7043e47bb3d96b790085010
https://doi.org/10.2174/1871527311312010016
https://doi.org/10.2174/1871527311312010016
Autor:
David Hojnacki, Kailash C. Chadha, Johnson Joseph M, Nir Raphael, Channa Kolb, Zohara Sternberg, Adam Nir, Rayan George, Jinhee Yu
Publikováno v:
Neuropharmacology. 130
Background We investigated Fingolimod treatment effects on the RAGE (receptor for advanced glycation endproducts) axis in multiple sclerosis (MS) patients. The primary outcome of the study was whether Fingolimod treatment increases serum levels of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8369b2fff8fb5f091b1a4272fa963257
https://pubmed.ncbi.nlm.nih.gov/29197515
https://pubmed.ncbi.nlm.nih.gov/29197515
Autor:
Bindukumar Nair, Ravikumar Aalinkeel, Kailash C. Chadha, Jessica L. Reynolds, Stanley A. Schwartz, Supriya D. Mahajan, Donald E. Sykes
Publikováno v:
Immunological Investigations. 40:447-464
Matrix metallaprotinase-9 (MMP-9) is zinc-containing proteinase whose expression and trafficking are frequently altered in cancer. MMP-9 in the plasma membrane and the secreted forms are thought to contribute to the invasive and metastatic properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c204018c179dfa87e19d6eb91f2305
https://doi.org/10.3109/08820139.2011.557795
https://doi.org/10.3109/08820139.2011.557795
Autor:
Donald E. Sykes, Jessica L. Reynolds, Ravikumar Aalinkeel, B. Bindukumar, Supriya D. Mahajan, Stanley A. Schwartz, Kailash C. Chadha
Publikováno v:
The Prostate. 68:1773-1789
BACKGROUND Human and animal studies have suggested that diet-derived flavonoids, in particular quercetin may play a beneficial role by preventing or inhibiting oncogenesis, but the underlying mechanism remains unclear. The aim of this study is to eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff716a7bbe049b74cccb31d5f8cf541
https://doi.org/10.1002/pros.20845
https://doi.org/10.1002/pros.20845
Publikováno v:
Journal of Chromatography B. 861:227-235
Prostate-specific antigen (PSA) is a serine protease secreted both by normal prostate glandular epithelial cells and prostate cancer cells. We explored "thiophilic-interaction chromatography" (TIC) to isolate tissue prostate-specific antigen (T-PSA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c25a44ef7aca910afcd8d28504e8b3b9
https://doi.org/10.1016/j.jchromb.2007.11.039
https://doi.org/10.1016/j.jchromb.2007.11.039