Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kaila M. Pianalto"'
Autor:
Kaila M. Pianalto, J. Andrew Alspaugh
Publikováno v:
Journal of Fungi, Vol 2, Iss 4, p 26 (2016)
Recent investigations have yielded both profound insights into the mechanisms required by pathogenic fungi for virulence within the human host, as well as novel potential targets for antifungal therapeutics. Some of these studies have resulted in the
Externí odkaz:
https://doaj.org/article/d2bea5c5bf6a4220858e815b78e59b3a
Autor:
Jeffrey M Skerker, Kaila M Pianalto, Stephen J Mondo, Kunlong Yang, Adam P Arkin, Nancy P Keller, Igor V Grigoriev, N Louise Louise Glass
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 8 (2021)
Abstract Aspergillus flavusA. flavusA. flavusA. flavus
Externí odkaz:
https://doaj.org/article/eb2eaa81bbf2464fb5b8c8306f835192
Autor:
Shannon K Esher, Kyla S Ost, Maria A Kohlbrenner, Kaila M Pianalto, Calla L Telzrow, Althea Campuzano, Connie B Nichols, Carol Munro, Floyd L Wormley, J Andrew Alspaugh
Publikováno v:
PLoS Pathogens, Vol 14, Iss 6, p e1007126 (2018)
The human fungal pathogen, Cryptococcus neoformans, dramatically alters its cell wall, both in size and composition, upon entering the host. This cell wall remodeling is essential for host immune avoidance by this pathogen. In a genetic screen for mu
Externí odkaz:
https://doaj.org/article/eeac4427a615407a9b1fdb9e2afb7a60
Autor:
J. Andrew Alspaugh, Abhishek Chhetri, Mi Jung Kim, Anna Loksztejn, Kaila M. Pianalto, Hai P Nguyen, Kenichi Yokoyama, Jiyong Hong
Publikováno v:
Biochemistry. 59:682-693
(1,3)-β-D-Glucan synthase (GS) catalyzes formation of the linear (1,3)-β-D-glucan in the fungal cell wall, and is a target of clinically approved antifungal antibiotics. The catalytic subunit of GS, FKS protein, does not exhibit significant sequenc
Autor:
Igor V. Grigoriev, Jeffrey M. Skerker, Nancy P. Keller, Kaila M. Pianalto, N. Louise Glass, Adam P. Arkin, Kunlong Yang, Stephen J. Mondo
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 11, Iss 8 (2021)
G3: Genes, Genomes, Genetics, Vol 11, Iss 8 (2021)
Aspergillus flavus is an opportunistic pathogen of crops, including peanuts and maize, and is the second leading cause of aspergillosis in immunocompromised patients. A. flavus is also a major producer of the mycotoxin, aflatoxin, a potent carcinogen
Autor:
Kaila M. Pianalto, K. D. Mueller, M Del Poeta, Hannah E. Brown, J. A. Alspaugh, Caroline Mota Fernandes
The ability for cells to internalize extracellular cues allows them to adapt to novel and stressful environments. This adaptability is especially important for microbial pathogens that must sense and respond to drastic changes when encountering the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eac378c818e4e3507530f70e2de0ee2
https://doi.org/10.1101/2020.10.19.345280
https://doi.org/10.1101/2020.10.19.345280
Autor:
Connie B. Nichols, Nuria Trevijano-Contador, Kaila M. Pianalto, J. Andrew Alspaugh, Liise Anne Pirofski, Oscar Zaragoza
Publikováno v:
Infect Immun
Human studies have shown associations between cryptococcal meningitis and reduced IgM memory B cell levels, and studies in IgM- and/or B cell-deficient mice have demonstrated increased Cryptococcus neoformans dissemination from lungs to brain. Since
Publikováno v:
Journal of Biological Chemistry. 293:9995-10008
Pathogenic microorganisms must adapt to changes in their immediate surroundings, including alterations in pH, to survive the shift from the external environment to that of the infected host. In the basidiomycete fungal pathogen Cryptococcus neoforman
Publikováno v:
Genetics
Limited antifungal diversity and availability are growing problems for the treatment of fungal infections in the face of increasing drug resistance. The echinocandins, one of the newest classes of antifungal drugs, inhibit production of a crucial cel
Limited antifungal diversity and availability are growing problems for the treatment of fungal infections in the face of increasing drug resistance. The echinocandins, one of the newest classes of antifungal drugs, inhibit production of a crucial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2905c368a423c6ebb73a56342b48570