Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Kaijun Di"'
Publikováno v:
bioRxiv
Cancer-related cognitive impairments (CRCI) are debilitating consequences of cancer treatment with platinum agents (e.g., cisplatin) that greatly alter cancer survivors’ health-related quality of life. Brain-derived neurotrophic factor (BDNF) plays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093e7e093e7514dec91401ab5a1f4ce9
https://europepmc.org/articles/PMC10245559/
https://europepmc.org/articles/PMC10245559/
Autor:
Chris Douglas, Naomi Lomeli, Javier Lepe, Kaijun Di, Nitesh Kumar Nandwana, Thao Vu, James Pham, Maria Cristina Kenney, Bhaskar Das, Daniela A. Bota
Publikováno v:
bioRxiv
Malignant astrocytomas are aggressive glioma tumors that have poor prognosis and limited treatments available following recurrence. These tumors are characterized by extensive hypoxia-induced, mitochondria-dependent changes such as glycolytic respira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc30851249d5782bac0bbc4872d1c46
https://europepmc.org/articles/PMC10153114/
https://europepmc.org/articles/PMC10153114/
Autor:
John S. Lowengrub, Daniela A. Bota, Christopher C.W. Hughes, Hermann B. Frieboes, Kaijun Di, Lesly I. Benitez, Mónica Romero-López, Huaming Yan
The nondimensionalization of the mathematical model, model parameters, and detailed analysis of the results in Main Text, including 2D slices and volume fractions of each cell type in Control and tumors treated by anti-angiogenic, anti-mitotic, diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed5e5ae34994b553b702e416eafff9c
https://doi.org/10.1158/0008-5472.22414898
https://doi.org/10.1158/0008-5472.22414898
Autor:
John S. Lowengrub, Daniela A. Bota, Christopher C.W. Hughes, Hermann B. Frieboes, Kaijun Di, Lesly I. Benitez, Mónica Romero-López, Huaming Yan
Glioblastoma (GBM), the most aggressive brain tumor in human patients, is decidedly heterogeneous and highly vascularized. Glioma stem/initiating cells (GSC) are found to play a crucial role by increasing cancer aggressiveness and promoting resistanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::780749c0cfe97240ffa3b9f157c08431
https://doi.org/10.1158/0008-5472.c.6509108.v1
https://doi.org/10.1158/0008-5472.c.6509108.v1
Autor:
Javier Lepe, Clay Hoerig, Naomi Lomeli, Ashley Plant-Fox, Christopher J. Douglas, Bhaskar Das, Kaijun Di, Daniela A. Bota
Publikováno v:
Neuro-Oncology, vol 23, iss Supplement_6
Neuro-oncology, vol 23, iss Suppl 6
Neuro Oncol
Neuro-oncology, vol 23, iss Suppl 6
Neuro Oncol
BACKGROUND Brain tumors are the second most common type of pediatric cancer and are the leading cause of all cancer-related deaths in children. Medulloblastoma (MB) is the most common type of malignant pediatric brain tumor and has a five-year overal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678bd814b77211cded51e54525e96c81
https://escholarship.org/uc/item/699783dr
https://escholarship.org/uc/item/699783dr
Publikováno v:
Neuro-Oncology, vol 23, iss Supplement_6
Neuro Oncol
Neuro Oncol
Glioblastoma (GBM), a WHO grade IV brain cancer, exhibits strong treatment resistance and a high rate of reoccurrence, which gives it a dismal prognosis, a 5% survival rate in the first 5 years. LonP1, a mitochondrial master regulator, can drive meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071f053b5f31147cd95e1ed800543016
https://escholarship.org/uc/item/7vf4s9p3
https://escholarship.org/uc/item/7vf4s9p3
Publikováno v:
Neuro-Oncology. 24:vii262-vii262
The dynamic nature of tumor microenvironments contributes to tumor heterogeneity generating subpopulations of cells that are resistant to treatment in glioblastoma (GBM). The high recurrent rate of GBM tumors in patients can partially be explained by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40d0de2d2fce55f058a10f74ce4f5be8
https://doi.org/10.1093/neuonc/noac209.1010
https://doi.org/10.1093/neuonc/noac209.1010
Publikováno v:
Neuro-Oncology. 24:vii220-vii220
TRIM11 (tripartite motif-containing protein 11) belongs to the TRIM/RBCC (the RING B-box coiled-coil) family of E3 ubiquitin ligases. Members of this family have been implicated in development, neurodegenerative diseases, cellular response to viral i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77a083dfae988772ff782919eba694e9
https://doi.org/10.1093/neuonc/noac209.848
https://doi.org/10.1093/neuonc/noac209.848
Publikováno v:
Neuro-Oncology. 24:vii37-vii37
Glioblastoma (GBM), a high grade brain tumor, possesses poor overall survival with less than 5% surviving past five years. Previously, the TCGA classifications for GBM have included the mesenchymal, proneural, classical and neural subtypes with their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e32a51e7cdff823eb3b5c33012ffd5cb
https://doi.org/10.1093/neuonc/noac209.145
https://doi.org/10.1093/neuonc/noac209.145
Publikováno v:
Pediatric Blood & Cancer. 68
Ubiquitin proteasome-mediated protein degradation has been implicated in posttranslational oncogenesis in medulloblastoma. Current research is evaluating the clinical implications of proteasome inhibition as a therapeutic target. In medulloblastoma c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6055a18798fbd89953d2858776037d36
https://doi.org/10.1002/pbc.29168
https://doi.org/10.1002/pbc.29168