Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kaijiro Maeda"'
Autor:
Kazumasa Fujitani, Fumio Nagashima, Kensei Yamaguchi, Taroh Satoh, Mika Tsujimoto, Yasushi Omuro, Tomohiro Nishina, Kaijiro Maeda, Toshiko Koue, Nozomu Machida
Publikováno v:
Gastric Cancer. 21:1041-1049
Ramucirumab, a monoclonal antibody vascular endothelial growth factor receptor-2 antagonist, given as monotherapy improved survival in a global phase 3 study (REGARD) of patients with gastric cancer. However, REGARD did not include Japanese patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac8fa4ed292525af554c4c5e1e7a579
https://doi.org/10.1007/s10120-018-0811-4
https://doi.org/10.1007/s10120-018-0811-4
Autor:
Chihiro, Tamaki, Shinichi, Hayashi, Aki, Sato, Kaijiro, Maeda, Sachi, Sakaguchi, Sean, Buchanan, Sotaro, Enatsu
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 46(9)
Abemaciclib, a selective cyclin dependent kinases 4 and 6(CDK46)inhibitor, is under development for the treatment of hormone receptor(HR)-positive, HER2-negative breast cancer. CDK46 inhibitors attenuate Rb phosphorylation resulting in a G1 arrest an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bdbbd19731917499ead7d846a3556ba5
https://pubmed.ncbi.nlm.nih.gov/31530780
https://pubmed.ncbi.nlm.nih.gov/31530780
Autor:
Kensei Tobinai, Kazunori Uenaka, Tsuyoshi Ishiki, Soshi Nagaoka, Shinsuke Iida, Hiroya Asou, Kaijiro Maeda, Daisuke Ogiya, Masafumi Taniwaki, Yasunobu Abe, Ilaria Conti
Publikováno v:
Cancer Science
B-cell activating factor (BAFF) promotes the survival and adhesion of multiple myeloma (MM) cells. Tabalumab (LY2127399) is an anti-BAFF monoclonal antibody. This phase 1, multicenter, open-label, nonrandomized, dose-escalation study evaluated the sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a88b4bdfa482529888010d8bb1968f
https://doi.org/10.1111/cas.13000
https://doi.org/10.1111/cas.13000
Autor:
Yoon-Koo Kang, Yasuo Hamamoto, Reigetsu Yoshikawa, Kei Muro, Toshihiro Kudo, Akichika Ozeki, Shuichi Hironaka, Shigenori Kadowaki, Yuko Kitagawa, Keisho Chin, Kohei Shitara, Li Yuan Bai, Do Youn Oh, Takaki Yoshikawa, Chia Jui Yen, Kazuhiro Yoshida, Hyun Cheol Chung, Kaijiro Maeda, Yasushi Omuro
Publikováno v:
JAMA Network Open. 2:e198243
IMPORTANCE: Ramucirumab, a human IgG 1 antibody against vascular endothelial growth factor receptor 2, has been shown to improve progression-free survival and overall survival in patients with advanced gastric cancer in the second-line setting. OBJEC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda25110b10205f5274c5a2f06ae6771
https://doi.org/10.1001/jamanetworkopen.2019.8243
https://doi.org/10.1001/jamanetworkopen.2019.8243
Autor:
Ayako Mitsuma, Toru Mukohara, Masataka Sawaki, Robert Ilaria, Naomi Kiyota, Megumi Inada-Inoue, Yutaka Fujiwara, P. Kellie Turner, Hironobu Minami, Naoko Chayahara, Jumpei Funai, Yuichi Ando, Kaijiro Maeda
Publikováno v:
Cancer Chemotherapy and Pharmacology. 71:991-998
This phase I study was designed to determine the maximum tolerated dose (MTD) and the dose to be recommended for a future phase II study of tasisulam sodium in Japanese patients with advanced, refractory solid tumors. Safety, pharmacokinetics and pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ff058c0f7c9e00a8739982d962ab17
https://doi.org/10.1007/s00280-013-2092-2
https://doi.org/10.1007/s00280-013-2092-2
Autor:
Li Yuan Bai, Hyun Cheol Chung, Shigenori Kadowaki, Shuichi Hironaka, Kaijiro Maeda, Yasuo Hamamoto, Keisho Chin, Yuko Kitagawa, Toshihiro Kudo, Kohei Shitara, Akichika Ozeki, Yoon-Koo Kang, Chia Jui Yen, Do-Youn Oh, Kazuhiro Yoshida, Takaki Yoshikawa, Yasushi Omuro, Kei Muro, Reigetsu Yoshikawa
Publikováno v:
Journal of Clinical Oncology. 36:4036-4036
4036Background: RAM (a human IgG1 antibody against vascular endothelial growth factor receptor-2) plus paclitaxel has been found to improve overall survival compared with paclitaxel alone as second...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cfb065a08589116f24934f6e000ee99
https://doi.org/10.1200/jco.2018.36.15_suppl.4036
https://doi.org/10.1200/jco.2018.36.15_suppl.4036
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 40(11)
This report summarizes the use of gemcitabine for the treatment of malignant lymphoma. Gemcitabine is a deoxycytidine antagonist that has characteristics different from those of the deoxycytidine antagonist cytarabine(Ara-C). International guidelines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8701e6ab424ba3cd4aba842ad438276
https://pubmed.ncbi.nlm.nih.gov/24231701
https://pubmed.ncbi.nlm.nih.gov/24231701
Autor:
Masami, Ishii, Soshi, Nagaoka, Masumi, Tatsumi, Natsuko, Kitagawa, Masanori, Taketsuna, Sumiko, Okubo, Kaijiro, Maeda, Kohji, Takeuchi
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 38(13)
To elucidate the detailed profiles of major adverse events associated with gemcitabine hydrochloride, such as myelosuppression and interstitial pneumonitis (IP), we reanalyzed the results from Japanese clinical studies conducted by Eli Lilly Japan K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db9814ce496ab48c550c593c02c95f68
https://pubmed.ncbi.nlm.nih.gov/22189227
https://pubmed.ncbi.nlm.nih.gov/22189227
Publikováno v:
Chemical and Pharmaceutical Bulletin. 39:1958-1961
Three new triterpene glycosides, hebevinosides XII, XIII and XIV, were isolated besides five already known neurotoxic hebevinosides from acetone extract of the mycelium with primordia of a poisonous mushroom, Hebeloma vinosophyllum, and their structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a5a0d60ea421bacc836f0f7f12b67b2
https://doi.org/10.1248/cpb.39.1958
https://doi.org/10.1248/cpb.39.1958
Publikováno v:
Journal of Heterocyclic Chemistry. 25:937-942
A general method for the preparation of 4,5-dihydro-, 1,2,4,5-tetrahydro-, 4,5,6,7-tetrahydro- and 1,2,4,5,6,7-hexahydroazepino[3,2,1-hi]indoles was established by using intramolecular Friedel-Crafts alkylation of chloromethylthioacetamide as a cruci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb3dcd458be319827a7a1a17d8333f34
https://doi.org/10.1002/jhet.5570250345
https://doi.org/10.1002/jhet.5570250345