Zobrazeno 1 - 10
of 307
pro vyhledávání: '"Kaija-Leena Kolho"'
Autor:
Brandon Hickman, Anne Salonen, Alise J. Ponsero, Roosa Jokela, Kaija-Leena Kolho, Willem M. de Vos, Katri Korpela
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The human gut microbiota is central in regulating all facets of host physiology, and in early life it is thought to influence the host’s immune system and metabolism, affecting long-term health. However, longitudinally monitored cohorts wi
Externí odkaz:
https://doaj.org/article/3bacf662c565486f8192020aa2f78c1e
Autor:
Mira Kallio, Anna Tornivuori, Päivi J. Miettinen, Kaija-Leena Kolho, Heikki Relas, Evelyn Culnane, Hayley Loftus, Susan M. Sawyer, Silja Kosola
Publikováno v:
BMC Pediatrics, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Heath-related quality of life (HRQoL) is lower in adolescents with chronic health conditions compared to healthy peers. While there is evidence of some differences according to the underlying condition and gender, differences by m
Externí odkaz:
https://doaj.org/article/16dda1ae350d4fd9a799fb2b8dc13701
Autor:
Roosa Jokela, Katariina MM Pärnänen, Alise J Ponsero, Leo Lahti, Kaija-Leena Kolho, Willem M de Vos, Anne Salonen
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Antibiotic resistance genes (ARGs) are prevalent in the infant gut microbiota and make up the intestinal resistome, representing a community ARG reservoir. This study focuses on the dynamics and persistence of ARGs in the early gut microbiota, and th
Externí odkaz:
https://doaj.org/article/94b1063b776347419029f79ea249026d
Autor:
Dollwin Matharu, Alise J. Ponsero, Marton Lengyel, Agnes Meszaros-Matwiejuk, Kaija-Leena Kolho, Willem M. de Vos, Dora Molnar-Gabor, Anne Salonen
Publikováno v:
EBioMedicine, Vol 104, Iss , Pp 105182- (2024)
Summary: Background: Human milk oligosaccharides (HMOs), their determinants, infant gut microbiota and health are under extensive research; however, seldom jointly addressed. Leveraging data from the HELMi birth cohort, we investigated them collectiv
Externí odkaz:
https://doaj.org/article/7207f96d44c9485ea6746449e9ffb694
Autor:
Petri Vänni, Mysore V. Tejesvi, Niko Paalanne, Kjersti Aagaard, Gail Ackermann, Carlos A. Camargo, Merete Eggesbø, Kohei Hasegawa, Anne G. Hoen, Margaret R. Karagas, Kaija-Leena Kolho, Martin F. Laursen, Johnny Ludvigsson, Juliette Madan, Dennis Ownby, Catherine Stanton, Jakob Stokholm, Terhi Tapiainen
Publikováno v:
mSystems, Vol 8, Iss 6 (2023)
ABSTRACT Combining and comparing microbiome data from distinct infant cohorts has been challenging because such data are inherently multidimensional and complex. Here, we used an ensemble of machine-learning (ML) models and studied 16S rRNA amplicon
Externí odkaz:
https://doaj.org/article/032d0b21c79a4db4a7e354b958af92ca
Autor:
Kaija-Leena Kolho, Susan Sawyer, Silja Kosola, Evelyn Culnane, Anna Tornivuori, Mira Kallio, Päivi Miettinen
Publikováno v:
BMJ Paediatrics Open, Vol 7, Iss 1 (2023)
Background To investigate disease control, psychiatric comorbidity, substance use and their possible associations in adolescents with chronic medical conditions before transfer to adult healthcare.Methods We collected clinical data from the year prec
Externí odkaz:
https://doaj.org/article/1acde5554ae841d78200820cdcd35617
Autor:
Madeleine Spatz, Gregory Da Costa, Rebecka Ventin-Holmberg, Julien Planchais, Chloé Michaudel, Yazhou Wang, Camille Danne, Alexia Lapiere, Marie-Laure Michel, Kaija-Leena Kolho, Philippe Langella, Harry Sokol, Mathias L. Richard
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-18 (2023)
Abstract Background Effects of antibiotics on gut bacteria have been widely studied, but very little is known about the consequences of such treatments on the fungal microbiota (mycobiota). It is commonly believed that fungal load increases in the ga
Externí odkaz:
https://doaj.org/article/47c5ad1317204132903184b51dff9645
Autor:
Evgenia Dikareva, Dollwin Matharu, Emilia Lahtinen, Kaija-Leena Kolho, Willem M. De Vos, Anne Salonen, Alise J. Ponsero
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Background and aimsThe acquisition and gradual maturation of gut microbial communities during early childhood is central to an individual’s healthy development. Bacteriophages have the potential to shape the gut bacterial communities. However, the
Externí odkaz:
https://doaj.org/article/7e1418f59e8a4b78aef57fa6be74f866
Autor:
Susanna Gardemeister, Kirsi Skogberg, Terhi Saisto, Anne Salonen, Willem M. de Vos, Katri Korpela, Kaija-Leena Kolho
Publikováno v:
BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Purpose In developed countries, data on the frequency of antibiotics given to mothers during childbirth are limited beyond the overall effect of all various prophylactic indications. Also, data on the impact of such antibiotics to the well-b
Externí odkaz:
https://doaj.org/article/6fe2adc16c0f49508a5f8c023d82b0ce
Publikováno v:
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-5 (2022)
Abstract Background The incidence of pediatric inflammatory bowel disease (PIBD) has increased dramatically during the past decades. This implies involvement of environmental factors in etiology but lends no clues about specific agents. We evaluated
Externí odkaz:
https://doaj.org/article/d2b0bcd654d44c3098ab12fb0d038d7d