Zobrazeno 1 - 10 of 38 pro vyhledávání: '"Kaido P. Hanson"'
1
Mechanisms of lung cancer
Autor: Evgeny N. Imyanitov, Kaido P. Hanson, Ekatherina Sh. Kuligina, Alexandr V. Togo, Evgeniya V. Belogubova
Publikováno v: Drug Discovery Today: Disease Mechanisms. 2:213-223
Lung cancer (LC) is the most common tumor type and the leading cause of cancer-related deaths. The distinct feature of LC molecular pathogenesis is a frequent involvement of small intragenic mutations. This property holds a great promise for the deve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52d6471259ac58c5704413c63dec7e82
https://doi.org/10.1016/j.ddmec.2005.05.015
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3
NBS1 657del5 mutation may contribute only to a limited fraction of breast cancer cases in Russia
Autor: Anna P. Sokolenko, Evgeny N. Suspitsin, Cees J. Cornelisse, Elena M. Bit-Sava, Peter Devilee, Oleg L. Chagunava, Yulia R. Lazareva, Vladimir Semiglazov, Konstantin G. Buslov, Matsko De, Evgeny N. Imyanitov, Turkevich Ea, Aglaya G. Iyevleva, Alexandr V. Togo, Kaido P. Hanson, Ekatherina Sh. Kuligina, Elena V. Chekmariova
Publikováno v: International Journal of Cancer. 114:585-589
The gene for Nijmegen chromosomal breakage syndrome (NBS1) plays a role in a variety of processes protecting chromosomal stability. Recently, it was suggested in a Polish case-control study that the founder hypomorphic mutation in NBS1, 657del5, whic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91e89dd1b0b49755e745fe5922b0e34
https://doi.org/10.1002/ijc.20765
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4
Mechanisms of breast cancer
Autor: Kaido P. Hanson, Evgeny N. Imyanitov
Publikováno v: Drug Discovery Today: Disease Mechanisms. 1:235-245
Breast cancer is the first human tumor for which targeted therapies have been developed. The most impressive success stories include estrogen receptor pathway downregulators (tamoxifen and aromatase inhibitors) and HER2 antagonists (Herceptin). The d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e738d0b64482a180b07df894de910ee5
https://doi.org/10.1016/j.ddmec.2004.09.002
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5
Searching for cancer-associated gene polymorphisms: promises and obstacles
Autor: Alexandr V. Togo, Kaido P. Hanson, Evgeny N. Imyanitov
Publikováno v: Cancer Letters. 204:3-14
Low-penetrance genetic variations appear to form the most essential component of the heritability of cancer risk. Search for relevant polymorphic candidates faces significant obstacles, due to both the high number of potentially promising single nucl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a25fedac06e5f9b44324e5f8f10aa8
https://doi.org/10.1016/j.canlet.2003.09.026
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6
Molecular pathogenesis of bilateral breast cancer
Autor: Kaido P. Hanson, Evgeny N. Imyanitov
Publikováno v: Cancer Letters. 191:1-7
Bilateral breast cancer (biBC) offers intriguing possibilities for molecular genetic investigations, however it is disproportionally less studied than its unilateral counterpart. By now, genetic research has succeeded to resolve at least two importan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a37871425904aa0f97cafe0fb0e546f
https://doi.org/10.1016/s0304-3835(02)00523-2
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7
Expression of Caspase-3 and -7 Does Not Correlate with the Extent of Apoptosis in Primary Breast Carcinomas
Autor: Kazymir M. Pozharissky, Boris Zhivotovsky, Evgeny N. Imyanitov, Kaido P. Hanson, Maxim Yu. Grigoriev
Publikováno v: Cell Cycle. 1:326-331
Association between the rate of apoptosis and expression of the several relevant molecules (Bcl-2, pro- and active caspase-3, and caspase-7) was studied in 61 primary breast carcinomas. The rate of apoptosis detected both morphologically and by the T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc9dc836d50f1c62ce4f340c74fcdfe9
https://doi.org/10.4161/cc.1.5.152
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8
Distinct prevalence of the CYP19 Δ3(TTTA)7 allele in premenopausal versus postmenopausal breast cancer patients, but not in control individuals
Autor: Evgeniya V. Belogubova, Ekatherina Sh. Kuligina, Evgeny N. Suspitsin, E.P. Sokolov, Charles Theillet, Alexandr V. Togo, M. Grigoriev, K. Pozharisski, Oleg L. Chagunava, Evgeny N. Imyanitov, Kaido P. Hanson, L. M. Berstein
Publikováno v: European Journal of Cancer. 38:1911-1916
The CYP19 gene encodes the enzyme aromatase, which plays a key role in the conversion of androgens to oestrogens. A polymorphism in CYP19 in intron 4 (TTTA)n has been reported to be associated with breast cancer (BC) risk, although conflicting eviden
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50bc54f2024eddcf9008119413a6939f
https://doi.org/10.1016/s0959-8049(02)00149-1
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9
CYP19 gene polymorphism in endometrial cancer patients
Autor: Evgeny N. Suspitsin, Kaido P. Hanson, Poroshina Te, Anatolij Y. Kovalevskij, Vera B. Gamajunova, Lev M. Berstein, Alexandr V. Togo, Evgeny N. Imyanitov, Maxim Yu. Grigoriev, Dmitry A. Vasiljev, Evgeny P. Sokolov
Publikováno v: Journal of Cancer Research and Clinical Oncology. 127:135-138
Purpose: Initiation/promotion of endometrial cancer is known to be associated with estrogenic influence. Therefore, it is possible that some allelic polymorphisms of the genes involved in steroidogenesis or steroid metabolism contribute to endometria
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e294d5c0953a0b1ab13031f41d829d
https://doi.org/10.1007/s004320000200
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