Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Kaichiro Sawada"'
Autor:
Kenta Arai, Masaki Okumura, Young-Ho Lee, Hidekazu Katayama, Kenji Mizutani, Yuxi Lin, Sam-Yong Park, Kaichiro Sawada, Masao Toyoda, Hironobu Hojo, Kenji Inaba, Michio Iwaoka
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Seleno-insulin, a class of artificial insulin analogs, in which one of the three disulfide-bonds (S-S’s) of wild-type insulin (Ins) is replaced by a diselenide-bond (Se-Se), is attracting attention for its unique chemical and physiological
Externí odkaz:
https://doaj.org/article/3b226a8eb62b476ba0aaef9ad91a6b1c
Autor:
Masumi Kondo, Kaichiro Sawada, Yosuke Matsuda, Makiko Abe, Noriyuki Sanechika, Yumi Takanashi, Yoshitaka Mori, Moritsugu Kimura, Masao Toyoda
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1771 (2024)
Deuterium-depleted water (DDW) is used in the treatment of many diseases, including cancer and diabetes. To detect the effect of DDW on gene expression and activation of the insulin-responsive transporter GLUT4 as a mechanism for improving the pathol
Externí odkaz:
https://doaj.org/article/3ce4f6ca52ff4bd0a39a2c6e47f45f0c
Autor:
Takatoshi Kakuta, Kaichiro Sawada, Genta Kanai, Ryoko Tatsumi, Takayo Miyakogawa, Mari Ishida, Raima Nakazawa, Masafumi Fukagawa
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract Possible ectopic parathyroid hormone (PTH) production in adipose tissues surrounding hyperplastic parathyroid glands was examined in patients with secondary hyperparathyroidism (SHPT). In vitro culture of adipose tissues from 31 patients exc
Externí odkaz:
https://doaj.org/article/0b286d0d26094816af21af801472a8e2
Autor:
Nobumichi Saito, Masao Toyoda, Masumi Kondo, Makiko Abe, Noriyuki Sanechika, Moritsugu Kimura, Kaichiro Sawada, Masafumi Fukagawa
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 501 (2023)
(1) Background: Renal dysfunction and hypertension are mutually aggravating factors; however, the details of their interaction remain unclear. In a study using renal tissue from diabetic rats, we found that β1-integrin, a cell-substrate adhesion mol
Externí odkaz:
https://doaj.org/article/4d2d8ca123654e0eb02847a564f543e7
Autor:
Kaichiro Sawada, Masao Toyoda, Noriko Kaneyama, Sawako Shiraiwa, Hitomi Moriya, Han Miyatake, Eitaro Tanaka, Naoyuki Yamamoto, Masaaki Miyauchi, Moritsugu Kimura, Takehiko Wada, Masafumi Fukagawa
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
Background. Podocyte injury plays an important role in the onset and progression of diabetic nephropathy (DN). Downregulation of α3β1-integrin expression in podocytes is thought to be associated with podocyte detachment from the glomerular basement
Externí odkaz:
https://doaj.org/article/3c20524eb79c49e69eb187de0de3f5fb
Autor:
Kaichiro Sawada, Masafumi Fukagawa, Masao Toyoda, Makiko Abe, Noriko Kaneyama, Moritsugu Kimura, Moe Ono, Nobumichi Saito, Hitomi Moriya, Masumi Kondo
The induction of a high blood pressure due to diabetic nephropathy depends on the increase in renin secretion from juxtaglomerular cells, but many aspects of how juxtaglomerular cells sense blood pressure changes in the afferent arteriole and consequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e29bf0990f8e8a2007d11c2fefff623b
https://doi.org/10.21203/rs.3.rs-236185/v1
https://doi.org/10.21203/rs.3.rs-236185/v1
Autor:
Nobumichi SAITO, Masao TOYODA, Moe ONO, Masumi KONDO, Hitomi MORIYA, Moritsugu KIMURA, Kaichiro SAWADA, Masafumi FUKAGAWA
Publikováno v:
Tokai Journal of Experimental & Clinical Medicine; Dec2021, Vol. 46 Issue 4, p172-179, 8p
Autor:
Naoto Hamano, Masafumi Fukagawa, Takehiko Wada, Michio Nakamura, Hirotaka Komaba, Hideyuki Yamato, Kaichiro Sawada, Hiroaki Ishida
Publikováno v:
Journal of bone and mineral metabolism. 38(4)
High-turnover bone disease is a major consequence of SHPT and may explain the high risk for fracture in patients with advanced chronic kidney disease (CKD). Bisphosphonates suppress bone turnover and improve bone strength, but their effects have not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a367ea518ae8e9d80c1c6a48c4cabf82
https://pubmed.ncbi.nlm.nih.gov/32140785
https://pubmed.ncbi.nlm.nih.gov/32140785
Autor:
Kaichiro Sawada, Naoto Hamano, Hideyuki Yamato, Yosuke Nakagawa, Hiroaki Ishida, Masafumi Fukagawa, Michio Nakamura, Hirotaka Komaba, Takehiko Wada
Publikováno v:
Nephrology Dialysis Transplantation. 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27cf9d9c1d79d98582f6c882e93f0980
https://doi.org/10.1093/ndt/gfz106.fp295
https://doi.org/10.1093/ndt/gfz106.fp295
Autor:
Nobumichi Saito, Masao Toyoda, Hitomi Moriya, Masafumi Fukagawa, Kaichiro Sawada, Moritsugu Kimura
Publikováno v:
Diabetes. 68
Diabetic nephropathy (DN) and hypertension exacerbate each other, but many aspects of the mechanisms between these two pathologies remain unclear. The juxtaglomerular cells (JGC) secrete renin and trigger the renin-angiotensin-aldosterone system invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::874c8506873b1f09ce78688df49be46f
https://doi.org/10.2337/db19-498-p
https://doi.org/10.2337/db19-498-p