Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kai-Zhong Fu"'
Publikováno v:
Pharmaceuticals, Vol 15, Iss 12, p 1552 (2022)
CF2H moiety has a significant potential utility in drug design and discovery, and the incorporation of CF2H into biologically active molecules represents an important and efficient strategy for seeking lead compounds and drug candidates. On the other
Externí odkaz:
https://doaj.org/article/f4b39e4bd6564fe2b53f6c1407b2e32c
Publikováno v:
Organic Chemistry Frontiers. 9:2141-2148
The first approach of photoredox catalyzed radical–radical cross-coupling difluoromethylation of C(sp3)−H bond was reported, featuring transition metal-free, good functional group tolerance, broad substrate scope and mild reaction conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06774e499b8f586d3865e28a9ab7590d
https://doi.org/10.1039/d2qo00192f
https://doi.org/10.1039/d2qo00192f
Publikováno v:
Organic Letters. 23:8482-8487
An elegant tandem reaction process for transferring N-allyl amide into CF2H-β-amino alcohol is described. This approach proceeded smoothly under visible light irradiation in the presence of a 3 mol % Ir complex, exhibiting a broad substrate scope an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf0711e33584938b69fa3c0bc34ada55
https://doi.org/10.1021/acs.orglett.1c03242
https://doi.org/10.1021/acs.orglett.1c03242