Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kai-Zhi Jia"'
Publikováno v:
Microbial Biotechnology, Vol 14, Iss 4, Pp 1462-1471 (2021)
Summary The enzymatic conversion of l‐methionine (l‐Met) into volatile organic sulfur‐containing compounds (VOSCs) plays an important role in developing the characteristic aroma of foods. However, the mechanism for the direct conversion of l‐
Externí odkaz:
https://doaj.org/article/747162c1e58e43069de3afbd85bde51d
Publikováno v:
Current Pharmaceutical Design. 28:1466-1479
Abstract: Flavonoid glycosides play determinant roles in plants and have considerable potential for applications in medicine and biotechnology. Glycosyltransferases transfer a sugar moiety from uridine diphosphateactivated sugar molecules to an accep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::433639755b06d28a92050a2b0f2e9f4c
https://doi.org/10.2174/1381612828666220422085128
https://doi.org/10.2174/1381612828666220422085128
Publikováno v:
Microbial Biotechnology, Vol 14, Iss 4, Pp 1462-1471 (2021)
Microbial Biotechnology
Microbial Biotechnology
Summary The enzymatic conversion of l‐methionine (l‐Met) into volatile organic sulfur‐containing compounds (VOSCs) plays an important role in developing the characteristic aroma of foods. However, the mechanism for the direct conversion of l‐
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae93f3e14ca89529be3f42b95fb36298
https://doaj.org/article/747162c1e58e43069de3afbd85bde51d
https://doaj.org/article/747162c1e58e43069de3afbd85bde51d
Publikováno v:
ACS synthetic biology. 11(5)
Enzyme entrances, which function as the first molecular filters, influence substrate selectivity and enzymatic activity. Because of low binding affinities, engineering enzyme entrances that recognize non-natural substrates is a major challenge for ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2725b869aca5e132bbc19e77612df33
https://pubmed.ncbi.nlm.nih.gov/35522995
https://pubmed.ncbi.nlm.nih.gov/35522995
Autor:
Kai-Zhi Jia, Ya-Jie Tang, Yue-zhong Li, Hong-Mei Li, Shengying Li, Qi Qingsheng, Yuemao Shen, Xia Zhan, Youming Zhang
Publikováno v:
Process Biochemistry. 96:220-227
Biological modification of natural products is an important approach to improve the pharmacological properties. 4′-d-β-Demethylepipodophyllotoxin (4′-d-β-DMEP), a typical natural lignin, is used as the aglycon of topoisomerase inhibitor etoposi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49d5b4ddbdeb56ee55baaf46eb90cb75
https://doi.org/10.1016/j.procbio.2020.05.006
https://doi.org/10.1016/j.procbio.2020.05.006
Publikováno v:
Current pharmaceutical design. 28(18)
Flavonoid glycosides play determinant roles in plants and have considerable potential for applications in medicine and biotechnology. Glycosyltransferases transfer a sugar moiety from uridine diphosphateactivated sugar molecules to an acceptor flavon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d00bc41d59ad03a49aabaad4a3c0d9ec
https://pubmed.ncbi.nlm.nih.gov/35466866
https://pubmed.ncbi.nlm.nih.gov/35466866
Autor:
Yue-zhong Li, Ya-Jie Tang, Xudong Qu, Li-Wen Zhu, Youming Zhang, Qingsheng Qi, Yuemao Shen, Shengying Li, Kai-Zhi Jia
Publikováno v:
ACS Synthetic Biology. 8:2718-2725
The 4-O-β-d-glucopyranoside of DMEP ((-)-4'-desmethylepipodophyllotoxin) (GDMEP), a natural product from Podophyllum hexandrum, is the direct precursor to the topoisomerase inhibitor etoposide, used in dozens of chemotherapy regimens for various mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c275bee55b37f516d222c9a2b38296f
https://doi.org/10.1021/acssynbio.9b00318
https://doi.org/10.1021/acssynbio.9b00318
Autor:
Kai-Zhi, Jia, Li-Wen, Zhu, Xudong, Qu, Shengying, Li, Yuemao, Shen, Qingsheng, Qi, Youming, Zhang, Yue-Zhong, Li, Ya-Jie, Tang
Publikováno v:
ACS synthetic biology. 8(12)
The 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8cef7dda3bcca5d14c8342eb0a2720a6
https://pubmed.ncbi.nlm.nih.gov/31774653
https://pubmed.ncbi.nlm.nih.gov/31774653
Publikováno v:
Applied and environmental microbiology. 84(22)
Adaptation to environmental perturbations requires living systems to coordinately regulate signaling pathways, gene expression, and metabolism. To better understand the mechanisms underlying adaptation, the regulatory nodes within networks must be el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3b51b6112e913e1fbe0aa466d442ee
https://pubmed.ncbi.nlm.nih.gov/30217835
https://pubmed.ncbi.nlm.nih.gov/30217835
Publikováno v:
Scientific Reports
Eukaryote-derived methioninase, catalyzing the one-step degradation of methionine (Met) to methanethiol (MTL), has received much attention for its low immunogenic potential and use as a therapeutic agent against Met-dependent tumors. Although biologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3c6d951233aec3cd8804d084bf68e5