Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kai-Xing Huang"'
Publikováno v:
Synapse. 30:18-29
It has been proposed that dopamine and glutamate affect basal ganglia output, in part, through interactions between D1 receptors and NMDA receptors. The present study examined whether N-methyl-D-aspartate (NMDA) receptor antagonists affect the neurop
Publikováno v:
Acta pharmacologica Sinica. 34(5)
Aim: ubiquitin-proteasome system (uPS) and autophagosome-lysosome pathway (ALP) are the most important machineries responsible for protein degradation in Parkinson’s disease (PD). The aim of this study is to investigate the adaptive alterations in
Publikováno v:
Acta Pharmacologica Sinica
Aim: To develop a C. elegans model of amyotrophic lateral sclerosis (ALS) and to evaluate the role of autophagy in the disease. Methods: Stable transgenic worms expressing the G93A mutant form of Cu,Zn-superoxide dismutase (SOD1) in GABAergic motor n
Publikováno v:
Acta pharmacologica Sinica. 34(5)
As autophagy is involved in cell growth, survival, development and death, impaired autophagic flux has been linked to a variety of human pathophysiological processes, including neurodegeneration, cancer, myopathy, cardiovascular and immune-mediated d
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1306:179-186
The c-Fes proto-oncogene encodes a myeloid-specific protein-tyrosine kinase that is expressed preferentially in differentiated myeloid cells, but not in early myeloblast progenitor cells. To examine the basis for the phenotypic expression of c-Fes, t
Publikováno v:
Journal of neurochemistry. 96(2)
The mechanism of action of commonly used antidepressants remains an issue of debate. In the experiments reported here we studied the effects of three representative compounds, the selective serotonin reuptake inhibitor fluoxetine, the selective serot
Autor:
David R. Sibley, Debra A. Bergstrom, Kai-Xing Huang, Antonio M. Gonzalez, Deborah S. Kreiss, Judith R. Walters
Publikováno v:
European journal of pharmacology. 277(2-3)
The potencies for in vivo inhibition of substantia nigra pars compacta dopamine single cell firing were determined for apomorphine, BHT 920, N-0923, (±)-7-hydroxy-dipropylaminotetralin (7-OH-DPAT), (+)-3-(3-hydroxyphenyl)-N-propylpiperidine (3-PPP),
Publikováno v:
European journal of pharmacology. 231(3)
Repeated reserpine treatment (1 mg/kg×6 days) increased the number of spontaneously active substantia nigra pars compacta (SNC) dopamine (DA) cells and altered the firing pattern to a more irregular one in locally anesthetized rats. The selective DA
Publikováno v:
Journal of Neurochemistry; Jan2006, Vol. 96 Issue 2, p396-406, 11p, 4 Color Photographs, 1 Black and White Photograph, 1 Graph
Publikováno v:
Pharmacology and Functional Regulation of Dopaminergic Neurons ISBN: 9781349100491
Tetrahydroprotoberberines (THPBs) consist of an isoquinoline ring with MeO and/or OH groups. Among THPBs, (−)-tetrahydropalmitine (THP) is the first one to be listed as a remedy in the Chinese Pharmacopoeia (1977 and 1985 editions). Our earlier wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e26ef5317bee9ce833d0946c7ad1bb5
https://doi.org/10.1007/978-1-349-10047-7_7
https://doi.org/10.1007/978-1-349-10047-7_7