Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kai-Wen He"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Although an increasing number of disease genes have been identified, the exact cellular mechanisms of retinitis pigmentosa (RP) remain largely unclear. Retinal organoids (ROs) derived from the induced pluripotent stem cells (iPSCs) of patients provid
Externí odkaz:
https://doaj.org/article/9a14ec491e974854968ce64c5b8737fc
Autor:
Xiu-Feng Huang, Lue Xiang, Wan Cheng, Fei-Fei Cheng, Kai-Wen He, Bo-Wen Zhang, Si-Si Zheng, Ru-Yi Han, Yi-Han Zheng, Xiao-Tao Xu, Huan-Yun Yu, Wenjuan Zhuang, Yuk Fai Leung, Zi-Bing Jin
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 4, Pp 1-11 (2018)
Hereditary eye disease: Looking for blindness in the family tree In-depth genomic analysis of the family of a young man with severe visual impairment reveals a new gene involved in eye development. Ocular coloboma encompasses various hereditary disor
Externí odkaz:
https://doaj.org/article/34777f933ab945848b41bdcdce3d2b5d
Autor:
Wen-Li Deng, Mei-Ling Gao, Xin-Lan Lei, Ji-Neng Lv, Huan Zhao, Kai-Wen He, Xi-Xi Xia, Ling-Yun Li, Yu-Chen Chen, Yan-Ping Li, Deng Pan, Tian Xue, Zi-Bing Jin
Publikováno v:
Stem Cell Reports, Vol 10, Iss 4, Pp 1267-1281 (2018)
Summary: Retinitis pigmentosa (RP) is an irreversible, inherited retinopathy in which early-onset nyctalopia is observed. Despite the genetic heterogeneity of RP, RPGR mutations are the most common causes of this disease. Here, we generated induced p
Externí odkaz:
https://doaj.org/article/057a39d2e177461b8b7b95cf6cd7f0f7
Publikováno v:
Guoji Yanke Zazhi, Vol 14, Iss 3, Pp 416-418 (2014)
AIM: To research the curative effect of dexamethasone on rat cornea acid burn at different periods. METHODS: The 40 corneal acid burned eyes of the 40 SD rats were divided into 4 groups with each group of 10 eyes randomly. Ⅰ, Ⅱ, Ⅲ groups were t
Externí odkaz:
https://doaj.org/article/eedc8cf3f1134eff969110b53172d1ab
Autor:
Jun-Ying Wang, Guo-Ming Ma, Xiao-Qiang Tang, Qi-Li Shi, Ming-Can Yu, Min-Min Lou, Kai-Wen He, Wen-Yuan Wang
Publikováno v:
Brain. 146:2107-2119
Synaptic dysfunction is one of the earliest pathological processes that contribute to the development of many neurological disorders, including Alzheimer’s disease and frontotemporal lobar degeneration. However, the synaptic function of many diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d72a128e8dcb03cabf9c86f6a98e0779
https://doi.org/10.1093/brain/awac411
https://doi.org/10.1093/brain/awac411
Publikováno v:
The EMBO journalReferences.
Parvalbumin-positive neurons (PVs) are the main class of inhibitory neurons in the mammalian central nervous system. By examining diurnal changes in synaptic and neuronal activity of PVs in the supragranular layer of the mouse primary visual cortex (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517e8022e2d128f3a248dc93704955e4
https://pubmed.ncbi.nlm.nih.gov/36477886
https://pubmed.ncbi.nlm.nih.gov/36477886
Publikováno v:
Progress in Neurobiology. 222:102404
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bdd29c76a7a6a227ef8ee0a8c252bf1
https://doi.org/10.1016/j.pneurobio.2023.102404
https://doi.org/10.1016/j.pneurobio.2023.102404
Parvalbumin-positive (PV) neurons, the main class of inhibitory neurons in the neocortex, play critical roles in maintaining normal brain function and are implicated in a variety of brain disorders. Here we found that their function is modulated in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b507880a1b892d101341002699f79013
https://doi.org/10.1101/2022.03.30.486351
https://doi.org/10.1101/2022.03.30.486351
Autor:
Yinying Zhao, Yun-E Zhao, Xiu-Feng Huang, Zi-Bing Jin, Pingjun Chang, Zhen-Ji Chen, Jin Li, Hongfang Zhang, Kai-Wen He
Publikováno v:
Eye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645c62d2a07f1b673b99610e52fb4933
https://doi.org/10.1038/s41433-018-0277-y
https://doi.org/10.1038/s41433-018-0277-y
Autor:
Houfang Long, Weitong Zheng, Yang Liu, Yunpeng Sun, Kun Zhao, Zhenying Liu, Wencheng Xia, Shiran Lv, Zhengtao Liu, Dan Li, Kai-Wen He, Cong Liu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 5/18/2021, Vol. 118 Issue 20, p1-10, 10p