Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kai-Qiang Zhou"'
Autor:
Ya-Kun Zhang, Yuan-Yuan Qu, Yan Lin, Xiao-Hui Wu, Hou-Zao Chen, Xu Wang, Kai-Qiang Zhou, Yun Wei, Fushen Guo, Cui-Fang Yao, Xia-Di He, Li-Xia Liu, Chen Yang, Zong-Yuan Guan, Shi-Dong Wang, Jianyuan Zhao, De-Pei Liu, Shi-Min Zhao, Wei Xu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Overnutrition has been linked to increased risk of cancer. Here, the authors show that exceeding nutrients suppress Enoyl-CoA hydratase-1 (ECHS1) activity by inducing its acetylation resulting in accumulation of fatty acids and branched-chain amino a
Externí odkaz:
https://doaj.org/article/d46815d31f134af6aa2e2ea7608d395c
Autor:
Yan Lin, Chen Yang, Yakun Zhang, Xiaohui Wu, Xu Wang, De-Pei Liu, Wei Xu, Jian-Yuan Zhao, Shi-Dong Wang, Cui-Fang Yao, Lixia Liu, Yun Wei, Yuan-Yuan Qu, Kai-Qiang Zhou, Hou-Zao Chen, Shimin Zhao, Zong-Yuan Guan, Fushen Guo, Xia-Di He
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Nature Communications
Nature Communications
The oncogenic mechanisms of overnutrition, a confirmed independent cancer risk factor, remain poorly understood. Herein, we report that enoyl-CoA hydratase-1 (ECHS1), the enzyme involved in the oxidation of fatty acids (FAs) and branched-chain amino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dab7a1372da02907d5f8213b6df3b6f7
https://doi.org/10.1038/s41467-017-00489-5
https://doi.org/10.1038/s41467-017-00489-5
Publikováno v:
Applied Mechanics and Materials. 577:236-239
In order to improve quality of wheelset assembly, a method for calculating interference between two sliding asperities that corresponding to the wheelset assembly interference is presented. A finite element model of sliding spherical asperity has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::212e738a1759d4a2c60cff38062c33a3
https://doi.org/10.4028/www.scientific.net/amm.577.236
https://doi.org/10.4028/www.scientific.net/amm.577.236
Autor:
Ming Liang Ye, Yangyang Bian, Hanfa Zou, Shimin Zhao, Yuan Yuan Qu, Zexian Liu, Yan Lin, Kai Qiang Zhou, Yu Xue, Fang Xiu Luo, Wei Xu, Cui Fang Yao, Chang Liang He, Jian-Yuan Zhao
Publikováno v:
Scientific Reports
In cancer cells, the mammalian target of rapamycin complex 1 (mTORC1) that requires hormonal and nutrient signals for its activation, is constitutively activated. We found that overexpression of pyruvate kinase M2 (PKM2) activates mTORC1 signaling th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f85ca83c7b33916d29ee93e016a5fc