Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kai-Liu Shao"'
Autor:
Michael P. Gamcsik, Kai-Liu Shao, Susan M. Ludeman, O. Michael Colvin, David J. Adams, James B. Springer, Jila H. Boal, James L. Flowers
Publikováno v:
Cancer Chemotherapy and Pharmacology. 45:335-344
A number of investigators have observed that the use of 4-hydroperoxycyclophosphamide (4-HC) in multiwell plate cytotoxicity assays can be associated with toxicity to cells in wells that contain no drug. Previous reports have implicated diffusion of
Autor:
Gerald Zon, Bogdan Uznanski, Lawrence R. Phillips, Kathleen A. Gallo, Kai-liu Shao, Koziolkiewicz Maria, Wojciech J. Stec, Judith B. Regan
Publikováno v:
Nucleic Acids Research. 14:7405-7420
Protected deoxynucleoside 3'-O-ethyl-N,N-diisopropylphosphoramidite reagents were prepared for use in the automated synthesis of ethyl phosphotriester (Et) modified oligonucleotides. The title diastereomers were separated by reversed-phase HPLC, and
Autor:
Kathleen A. Gallo, Kai-liu Shao, R. Andrew Byrd, Carrie J. Samson, Michael F. Summers, Gerald Zon
Publikováno v:
Nucleic acids research. 13(22)
High-performance liquid chromatography (HPLC) and 1H/31P nuclear magnetic resonance (NMR) spectroscopy were used to measure the molar ratio of oligodeoxyribonucleotide products in mixtures obtained with automated DNA synthesizers that employed compet
Autor:
Kai Liu Shao, Shozo Takagi, V. L. Himes, Gerald Zon, S. M. Ludeman, K. Mizuta, Alan D. Mighell
Publikováno v:
Journal of medicinal chemistry. 26(12)
Nine representatives of the title series of compounds [(ClCH2CH2)2NP(O)(NH2)ON = CRR'] were synthesized as potential anticancer prodrugs, based on the possibility of enzymatic reduction of the N-O bond to release the known cytotoxic agent phosphorami
Autor:
Gunay Ozkan, Kai Liu Shao, Joan A. Brandt, Gerald Zon, William Egan, Victoria L. Boyd, S. M. Ludeman
Publikováno v:
Journal of medicinal chemistry. 27(4)
Multinuclear (31P, 13C, 2H, and 1H) Fourier-transform NMR spectroscopy, with and without isotopically enriched materials, was used to identify and quantify, as a function of time, the following intermediary (short-lived) metabolites of the anticancer
Autor:
Gerald Zon, Shozo Takagi, S. M. Ludeman, K. Mizuta, Alan D. Mighell, Kai Liu Shao, V. L. Himes
Publikováno v:
Chemischer Informationsdienst. 15
Nine representatives of the title series of compounds [(ClCH2CH2)2NP(O)(NH2)ON = CRR'] were synthesized as potential anticancer prodrugs, based on the possibility of enzymatic reduction of the N-O bond to release the known cytotoxic agent phosphorami