Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Kai-Hei Tse"'
Autor:
Hajime Takase, Gen Hamanaka, Ryo Ohtomo, Hidehiro Ishikawa, Kelly K. Chung, Emiri T. Mandeville, Josephine Lok, Myriam Fornage, Karl Herrup, Kai-Hei Tse, Eng H. Lo, Ken Arai
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
White matter damage caused by cerebral hypoperfusion is a major hallmark of subcortical ischemic vascular dementia (SIVD), which is the most common subtype of vascular cognitive impairment and dementia (VCID) syndrome. In an aging society, the number
Externí odkaz:
https://doaj.org/article/25f21b31cb26423c8c40c5188442765d
Autor:
Lok Hin Law, Jianpan Huang, Peng Xiao, Yang Liu, Zilin Chen, Joseph H.C. Lai, Xiongqi Han, Gerald W.Y. Cheng, Kai-Hei Tse, Kannie W.Y. Chan
Publikováno v:
Journal of Controlled Release. 354:208-220
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa2c7dcf4250cbfe58d4536245695b5b
https://doi.org/10.1016/j.jconrel.2023.01.011
https://doi.org/10.1016/j.jconrel.2023.01.011
Publikováno v:
NMR in Biomedicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b5feda747096e905a54018e9bd80346
https://doi.org/10.1002/nbm.4937
https://doi.org/10.1002/nbm.4937
Autor:
Joseph H. C. Lai, Lin Chen, Xiongqi Han, Jianpan Huang, Jiadi Xu, Kai Hei Tse, Zilin Chen, Kannie W. Y. Chan, Gerald W.Y. Cheng, Yang Liu
Publikováno v:
Magnetic Resonance in Medicine. 87:1529-1545
PURPOSE To optimize and apply deep neural network based CEST (deepCEST) and apparent exchange dependent-relaxation (deepAREX) for imaging the mouse brain with Alzheimer's disease (AD) at 3T MRI. METHODS CEST and T1 data of central and anterior brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82bb839b608c8b38ff6abccdf23374f2
https://doi.org/10.1002/mrm.29044
https://doi.org/10.1002/mrm.29044
Autor:
Askiel Bruno, Kai Hei Tse, Farzaneh A. Sorond, Jodi D. Edwards, Giuseppe Faraco, Anna Csiszar, Donna M. Wilcock, Zoltan Ungvari, Andy Y. Shih, Shawn N. Whitehead, S. Thomas Carmichael, Vladimir Hachinski, Deborah Gustafson, Gary A. Rosenberg, Frank C. Barone, Jeffrey M. Burns, Fanny M. Elahi, Douglas B. Gould, Kristen L. Zuloaga
Publikováno v:
GeroScience
Neuroscience Institute Publications
Neuroscience Institute Publications
White matter pathologies are critically involved in the etiology of vascular cognitive impairment-dementia (VCID), Alzheimer's disease (AD), and Alzheimer's disease and related diseases (ADRD), and therefore need to be considered a treatable target (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80bff1221571d8894b554264370a58f
https://doi.org/10.1007/s11357-021-00461-8
https://doi.org/10.1007/s11357-021-00461-8
Autor:
Kingston King‐Shi Mok, Sunny Hoi‐Sang Yeung, Gerald Wai‐Yeung Cheng, Iris Wai‐Ting Ma, Ralph Hon‐Sun Lee, Karl Herrup, Kai‐Hei Tse
Publikováno v:
Journal of neurochemistry.
Carriers of the APOE4 (Apolipoprotein E ε4) variant of the APOE gene are subject to several age-related health risks, including Alzheimer's disease (AD). The deficient lipid and cholesterol transport capabilities of the APOE4 protein are one reason
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::918d3138b6f27a00452b3767ea22a0e4
https://pubmed.ncbi.nlm.nih.gov/36549843
https://pubmed.ncbi.nlm.nih.gov/36549843
Autor:
Kai-Hei Tse, Wai-Mei Wong, Xiang-Yu Meng, Raymond Kin-Hi Hui, Daphne Lai-Han Wu, Martin Ho Yin Yeung
Publikováno v:
Pathology. 55:S77-S78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0205008ee155a13ed23d48ec7e2adde6
https://doi.org/10.1016/j.pathol.2022.12.257
https://doi.org/10.1016/j.pathol.2022.12.257
Autor:
Gerald Wai-Yeung Cheng, Kingston King-Shi Mok, Sunny Hoi-Sang Yeung, Julia Kofler, Karl Herrup, Kai-Hei Tse
Publikováno v:
J Neuropathol Exp Neurol
White matter degradation in the frontal lobe is one of the earliest detectable changes in aging and Alzheimer disease. The ε4 allele of apolipoprotein E (APOE4) is strongly associated with such myelin pathology but the underlying cellular mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66120eb9e1595ad0437eb23acff4369
https://doi.org/10.1093/jnen/nlac054
https://doi.org/10.1093/jnen/nlac054
Publikováno v:
Pathology. 55:S68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40c4cf7cf799b3898b0022b3d74067bd
https://doi.org/10.1016/j.pathol.2022.12.224
https://doi.org/10.1016/j.pathol.2022.12.224
Autor:
Cui Y, Kai Hei Tse, Julia Kofler, Zhu B, Jiang L, Cheng A, Cheng Gw, Wang Q, Yeung Sh, Karl Herrup
Ataxia-telangiectasia (A-T) is a rare genetic disease caused by mutations in the gene encoding the ATM (Ataxia-telangiectasia mutated) protein. Although neuronal degeneration in the cerebellum remains the most prominent sign in A-T, neuroimaging stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5390ebaef7d30071617c8b2a7aee8190
https://doi.org/10.1101/2021.01.22.20245217
https://doi.org/10.1101/2021.01.22.20245217
