Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Kai-Bo Wang"'
Publikováno v:
Engineering, Vol 38, Iss , Pp 39-51 (2024)
DNA guanine (G)-quadruplexes (G4s) are unique secondary structures formed by two or more stacked G-tetrads in G-rich DNA sequences. These structures have been found to play a crucial role in highly transcribed genes, especially in cancer-related onco
Externí odkaz:
https://doaj.org/article/758e276aab4243aba79bfbbf79874b32
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Gastric cancer (GC) remains the third leading cause of cancer-related mortality in the world, and ninety-five percent of GC are stomach adenocarcinomas (STAD). The active ingredients of Croci Stigma, such as Isorhamnetin, Crocin, Crocetin an
Externí odkaz:
https://doaj.org/article/6ad4b8adf69d44fc869ab29c4ebdd0d8
Autor:
Kai-Bo Wang, Yushuang Liu, Jinzhu Li, Chengmei Xiao, Yingying Wang, Wei Gu, Yipu Li, Yuan-Zheng Xia, Tingdong Yan, Ming-Hua Yang, Ling-Yi Kong
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The G-quadruplex formed in KRAS oncogene promoter (KRAS-G4) is a transcriptional modulator and amenable to small molecule targeting. Herein, the authors report the NMR solution structures of a bulge-containing KRAS-G4 that bound to two small molecule
Externí odkaz:
https://doaj.org/article/3a3ab16b284641808c7b23a21ff63551
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Changes in land use type can lead to variations in soil water characteristics. The objective of this study was to identify the responses of soil water holding capacity (SWHC) and soil water availability (SWA) to land use type (grassland, shr
Externí odkaz:
https://doaj.org/article/589ad96c107c49c7ac63efa9c83793df
Publikováno v:
Journal of Integrative Agriculture, Vol 11, Iss 12, Pp 2079-2087 (2012)
Grassland plays an important role in the global carbon cycle and climate regulation. However, there are still large uncertainties in grassland carbon pool and also its role in global carbon cycle due to the lack of measured grassland biomass at regio
Externí odkaz:
https://doaj.org/article/df786fe0c66c491aa88b98a27076c3b1
Autor:
Yan-Jun Sun, Li-Xin Pei, Kai-Bo Wang, Yin-Shi Sun, Jun-Min Wang, Yan-Li Zhang, Mei-Ling Gao, Bao-Yu Ji
Publikováno v:
Molecules, Vol 21, Iss 1, p 10 (2015)
Two prenylated biflavonoids, podoverines B–C, were isolated from the dried roots and rhizomes of Sinopodophyllum emodi using a Sephadex LH-20 column (SLHC) and high-speed counter-current chromatography (HSCCC). The 95% ethanol extract was partition
Externí odkaz:
https://doaj.org/article/5de750d970274ac48f535002320586a6
Publikováno v:
Advanced Materials Research. 1170:39-48
Corrosion behavior of 7A52 aluminum alloy plasma arc welding (PAW) joint was investigated in simulation of marine atmosphere environment with salt water spray test. The surface morphologies were observed by scanning electron microscopy (SEM), and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0a0545cebd16a0691dd61cae845559d
https://doi.org/10.4028/p-83qa4i
https://doi.org/10.4028/p-83qa4i
Autor:
Sheng-Ge Li, Xu Hu, Qin Zhang, Yan-Hui Zan, Kai-Bo Wang, Chun-Yu Jiang, Jing-Jing Xue, Yong-Xiang Liu, Bin Lin, Yong-Kui Jing, Da-Hong Li, Hui-Ming Hua
Publikováno v:
Organic & Biomolecular Chemistry. 20:8528-8532
Two pairs of unprecedented β-carboline-phenylpropanoid alkaloids, (±)-pheharmines A–B (1–4), characterized by a morpholino[4,3,2-hi]β-carboline core with two chiral centers, were isolated from the roots of Peganum harmala.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb044aad6173b5e3e0614c2764649684
https://doi.org/10.1039/d2ob01608g
https://doi.org/10.1039/d2ob01608g
Autor:
Danzhou Yang, Mark Cushman, Kai-Bo Wang, Mohamed S. Elsayed, Guanhui Wu, Adam J. Buric, Mercedes DeMoss
Publikováno v:
Cancer Research. 83:3103-3103
MYC is one of the most important oncogenes and is overexpressed in a number of human cancers. The G-quadruplex formed in the MYC oncogene promoter (MycG4) is a transcriptional silencer and amenable to small molecule targeting. G-quadruplexes are nonc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dcb4052756e78f55277697628da8283
https://doi.org/10.1158/1538-7445.am2023-3103
https://doi.org/10.1158/1538-7445.am2023-3103
Publikováno v:
Cancer Research. 83:3842-3842
PDGFR-β (Platelet-Derived Growth Factor Receptor beta) is a receptor tyrosine kinase whose overexpression drives the progression and metastasis of many cancers. It is an established anticancer target and PDGFR-β inhibition via kinase inhibitors has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::527d5023fd156d0a9146e57b037a38c9
https://doi.org/10.1158/1538-7445.am2023-3842
https://doi.org/10.1158/1538-7445.am2023-3842