Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kai Ying Soo"'
Autor:
CheukMan C Au, John B Furness, Kara Britt, Sofya Oshchepkova, Heta Ladumor, Kai Ying Soo, Brid Callaghan, Celine Gerard, Giorgio Inghirami, Vivek Mittal, Yufeng Wang, Xin Yun Huang, Jason A Spector, Eleni Andreopoulou, Paul Zumbo, Doron Betel, Lukas Dow, Kristy A Brown
Publikováno v:
eLife, Vol 9 (2020)
Breast cancer is the most common type of cancer in women and notwithstanding important therapeutic advances, remains the second leading cause of cancer-related death. Despite extensive research relating to the hormone ghrelin, responsible for the sti
Externí odkaz:
https://doaj.org/article/d89e185dd92b446193eb7a5df65c3161
Autor:
Paul Zumbo, Jason A. Spector, Eleni Andreopoulou, Brid Callaghan, Cheuk Man C. Au, Celine Gerard, Kai Ying Soo, Giorgio Inghirami, Vivek Mittal, Yufeng Wang, Xin-Yun Huang, Lukas E. Dow, Kara L. Britt, John B. Furness, Heta Ladumor, Kristy A. Brown, Doron Betel, Sofya Oshchepkova
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Breast cancer is the most common type of cancer in women and notwithstanding important therapeutic advances, remains the second leading cause of cancer-related death. Despite extensive research relating to the hormone ghrelin, responsible for the sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f886b308b033d78cc801cba1f77833
https://elifesciences.org/articles/56913
https://elifesciences.org/articles/56913
Autor:
Celine Gerard, Lukas E. Dow, Kristy A. Brown, Brid Callaghan, Kai Ying Soo, Sofya Oshchepkova, Paul Zumbo, John B. Furness, Kara L. Britt, Vivek Mittal, Xin-Yun Huang, Eleni Andreopoulou, Doron Betel, Heta Ladumor, Yufeng Wang, Jason A. Spector, Giorgio Inghirami, CheukMan C Au
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78040064ce26f1c721a2914fe03c0187
https://doi.org/10.7554/elife.56913.sa2
https://doi.org/10.7554/elife.56913.sa2
Autor:
Doron Betel, Kai Ying Soo, Paul Zumbo, Yufeng Wang, Celine Gerard, Heta Ladumor, Sofya Oshchepkova, Kristy A. Brown, Giorgio Inghirami, Lukas E. Dow, John B. Furness, CheukMan C Au, Vivek Mittal, Eleni Andreopoulou, Xin-Yun Huang, Jason A. Spector, Kara L. Britt, Brid Callaghan
Breast cancer is the most common type of cancer in women and notwithstanding important therapeutic advances, it remains the second leading cause of cancer-related death in the US. Despite extensive research relating to the hormone ghrelin, responsibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c9690b3f6902a82c1e8c67d9339ed6
https://doi.org/10.1101/2020.01.22.915744
https://doi.org/10.1101/2020.01.22.915744
Autor:
Julie D. Atkin, Ian P. Blair, Audrey Ragagnin, Gilles J. Guillemin, Natalie Grima, Sonam Parakh, Shu Yang, Kai-Ying Soo, Mark A. Halloran, Hamideh Shahheydari, Vinod Sundaramoorthy, Benjamin Heng, Marta Vidal
Publikováno v:
Cellular and molecular life sciences : CMLS. 77(19)
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are fatal neurodegenerative diseases that are related genetically and pathologically. Mutations in the UBQLN2 gene, encoding the ubiquitin-like protein ubiquilin2, are associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d013c263c0f1e66fa3cc238951db4ec
https://pubmed.ncbi.nlm.nih.gov/31802140
https://pubmed.ncbi.nlm.nih.gov/31802140
Autor:
Reka P. Toth, Peter Lock, Julie D. Atkin, Sonam Parakh, Mark A. Halloran, Katherine A. Southam, Catriona McLean, Vinod Sundaramoorthy, Manal A. Farg, Anna E. King, Kai-Ying Soo
Publikováno v:
Acta Neuropathologica. 130:679-697
Several diverse proteins are linked genetically/pathologically to neurodegeneration in amyotrophic lateral sclerosis (ALS) including SOD1, TDP-43 and FUS. Using a variety of cellular and biochemical techniques, we demonstrate that ALS-associated muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed69e42a9cce70ac54c5590e442c7c5
https://doi.org/10.1007/s00401-015-1468-2
https://doi.org/10.1007/s00401-015-1468-2
Autor:
Julie D. Atkin, Rak Atkinson, Ian P. Blair, Manal A. Farg, Sadaf T. Warraich, Vinod Sundaramoorthy, Ae King, Jessica M. Sultana, Kai-Ying Soo
Publikováno v:
Cell Death Discovery
Amyotrophic lateral sclerosis (ALS) is characterised by the formation of intracellular misfolded protein inclusions that form in motor neurons. Autophagy is the major degradation pathway for aggregate-prone proteins within lysosomes. Autophagy begins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36343712e6d0725b33f5ab3b05add370
https://doi.org/10.1038/cddiscovery.2015.30
https://doi.org/10.1038/cddiscovery.2015.30
Autor:
Manal A. Farg, Mark A. Halloran, Malcolm K. Horne, Phillip Nagley, Julie D. Atkin, Bradley J. Turner, Kai-Ying Soo, Adam K. Walker
Publikováno v:
Journal of neurochemistry. 129(1)
Cu/Zn-superoxide dismutase is misfolded in familial and sporadic amyotrophic lateral sclerosis, but it is not clear how this triggers endoplasmic reticulum (ER) stress or other pathogenic processes. Here, we demonstrate that mutant SOD1 (mSOD1) is pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d53b2b5dda374dbacf874f281b5e9d
https://pubmed.ncbi.nlm.nih.gov/24134191
https://pubmed.ncbi.nlm.nih.gov/24134191
Autor:
Manal A. Farg, Kai-Ying Soo, Adam K. Walker, Phillip Nagley, Malcolm K. Horne, Julie D. Atkin
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35413 (2012)
PLoS ONE
PLoS ONE
Endoplasmic reticulum (ER) stress is an important pathway to cell death in amyotrophic lateral sclerosis (ALS). We previously demonstrated that ER stress is linked to neurotoxicity associated with formation of inclusions of mutant Cu,Zn-superoxide di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926fbecb1b95b1da5406d70293d373dc
http://europepmc.org/articles/PMC3327676?pdf=render
http://europepmc.org/articles/PMC3327676?pdf=render
Publikováno v:
Journal of neurochemistry. 108(3)
Mutations in Cu, Zn-superoxide dismutase 1 (SOD1) are associated with degeneration of motor neurons in the disease, familial amyotrophic lateral sclerosis. Intracellular protein inclusions containing mutant SOD1 (mSOD1) are associated with disease bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e57c2abb71c56a6336f568950ca3dc
https://pubmed.ncbi.nlm.nih.gov/19046404
https://pubmed.ncbi.nlm.nih.gov/19046404