Discovery of Lysine Hydroxylases in the Clavaminic Acid Synthase-Like Superfamily for Efficient Hydroxylysine Bioproduction

Autor: Hiroshi Kawabata, Kai Yamagata, Kuniki Kino, Ryotaro Hara, Ryoma Miyake, Hisatoshi Uehara

Hydroxylation via C—H bond activation in the absence of any harmful oxidizing reagents is technically difficult in modern chemistry. In this work, we attempted to generate pharmaceutically important hydroxylysine from readily available l -lysine wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dea138b02933bac0649fdf4c43fba3d
https://europepmc.org/articles/PMC5561292/

Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of japanese society of chemotherapy, the japanese association for infectious diseases, and the japanese society for clinical microbiology in 2016: General view of the pathogens' antibacterial susceptibility.

Autor: Yanagihara K; The Surveillance Committee of the Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and the Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan; Nagasaki University School of Medicine, Nagasaki, Japan. Electronic address: k-yanagi@nagasaki-u.ac.jp., Matsumoto T; The Surveillance Committee of the Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and the Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan., Tokimatsu I; The Surveillance Committee of the Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and the Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan., Tsukada H; The Surveillance Committee of the Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and the Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan; Niigata City General Hospital, Niigata, Japan., Fujikura Y; The Surveillance Committee of the Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and the Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan; National Defense Medical College Hospital, Saitama, Japan., Miki M; The Surveillance Committee of the Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and the Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan., Morinaga Y; The Surveillance Committee of the Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and the Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan; Nagasaki University School of Medicine, Nagasaki, Japan., Sato J; The Surveillance Committee of the Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and the Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan., Wakamura T; The Surveillance Committee of the Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and the Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan., Kiyota H; The Surveillance Committee of the Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and the Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan., Tateda K; The Surveillance Committee of the Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and the Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan., Hanaki H; Infection Control Research Center, Kitasato University, Tokyo, Japan., Fujiuchi S; National Hospital Organization Asahikawa Medical Center, Hokkaido, Japan., Takahashi M; National Hospital Organization Asahikawa Medical Center, Hokkaido, Japan., Kayaba H; Hirosaki University Hospital, Aomori, Japan., Mori Y; Iwate Prefectural Central Hospital, Iwate, Japan., Takeda H; Saisei kai Yamagata Saisei Hospital, Yamagata, Japan., Ikeda H; Sanyudo Hospital, Yamagata, Japan., Takahashi H; Saka General Hospital, Miyagi, Japan., Konno M; Saka General Hospital, Miyagi, Japan., Niitsuma K; Fukushima Medical University Aizu Medical Center, Fukushima, Japan., Niki Y; Showa University School of Medicine, Tokyo, Japan., Takuma T; Showa University School of Medicine, Tokyo, Japan., Kawana A; National Defense Medical College Hospital, Saitama, Japan., Kudo M; Yokohama City University Hospital, Kanagawa, Japan., Hirano T; Yokohama City University Hospital, Kanagawa, Japan., Miyazawa N; Saiseikai Yokohamashi Nanbu Hospital, Kanagawa, Japan., Aso S; Niigata City General Hospital, Niigata, Japan., Aoki N; Shinrakuen Hospital, Niigata, Japan., Honma Y; Shinrakuen Hospital, Niigata, Japan., Yamamoto Y; Toyama University Hospital, Toyama, Japan., Iinuma Y; Kanazawa Medical University, Ishikawa, Japan., Mikamo H; Aichi Medical University Hospital, Aichi, Japan., Yamagishi Y; Aichi Medical University Hospital, Aichi, Japan., Nakamura A; Nagoya City University Hospital, Aichi, Japan., Kondo S; Nagoya City University Hospital, Aichi, Japan., Kawabata A; Toyota Memorial Hospital, Aichi, Japan., Sugaki Y; Toyota Memorial Hospital, Aichi, Japan., Yamamoto T; Asahi Rosai Hospital, Aichi, Japan., Nishi I; Osaka University Hospital, Osaka, Japan., Hamaguchi S; Osaka University Hospital, Osaka, Japan., Kakeya H; Osaka City University Hospital, Osaka, Japan., Fujikawa Y; Osaka City General Hospital, Osaka, Japan., Mitsuno N; Osaka City General Hospital, Osaka, Japan., Ukimura A; Osaka Medical College Hospital, Osaka, Japan., Yoshida K; Kindai University Hospital, Osaka, Japan., Hayashi M; Sumitomo Hospital, Osaka, Japan., Mikasa K; Center for Infectious Diseases, Nara Medical University, Nara, Japan., Kasahara K; Center for Infectious Diseases, Nara Medical University, Nara, Japan., Tokuyasu H; Matsue Red Cross Hospital, Shimane, Japan., Hino S; Matsue Red Cross Hospital, Shimane, Japan., Shimizu E; Tottori University Hospital, Tottori, Japan., Chikumi H; Tottori University Hospital, Tottori, Japan., Fujita M; Faculty of Medicine, Fukuoka University, Fukuoka, Japan., Kadota J; Oita University Faculty of Medicine, Oita, Japan., Hiramatsu K; Oita University Faculty of Medicine, Oita, Japan., Suga M; Saiseikai Kumamoto Hospital, Kumamoto, Japan., Muranaka H; Saiseikai Kumamoto Hospital, Kumamoto, Japan.

Publikováno v: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy [J Infect Chemother] 2020 Sep; Vol. 26 (9), pp. 873-881. Date of Electronic Publication: 2020 Jun 19.