Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kai Werle"'
Publikováno v:
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-16 (2017)
Abstract Background Man-made vitreous fibres (MMVF) are produced on a large scale for thermal insulation purposes. After extensive studies of fibre effects in the 1980ies and 1990ies, the composition of MMVF was modified to reduce the fibrotic and ca
Externí odkaz:
https://doaj.org/article/8cef188e49f845ce8143449a25ac6f00
Autor:
Willie J. G. M. Peijnenburg, Emmanuel Ruggiero, Matthew Boyles, Fiona Murphy, Vicki Stone, Derek A. Elam, Kai Werle, Wendel Wohlleben
Publikováno v:
Materials, Vol 13, Iss 10, p 2235 (2020)
The reactivity of particle surfaces can be used as a criterion to group nanoforms (NFs) based on similar potential hazard. Since NFs may partially or completely dissolve over the duration of the assays, with the ions themselves inducing a response, r
Externí odkaz:
https://doaj.org/article/a081336dcc6e4cfc9baccde1d1439b0f
Publikováno v:
Nanomaterials, Vol 10, Iss 2, p 311 (2020)
Dissolution rates of nanomaterials can be decisive for acute in vivo toxicity (via the released ions) and for biopersistence (of the remaining particles). Continuous flow systems (CFSs) can screen for both aspects, but operational parameters need to
Externí odkaz:
https://doaj.org/article/f8c5f4df29544c6da2a8efea6649bb21
Autor:
Veronica Di Battista, Agnieszka Gajewicz-Skrętna, Kai Werle, Lars Michael Skjolding, Nina Jeliazkova, Anders Baun, Wendel Wohlleben
Publikováno v:
Annals of Work Exposures and Health. 67:i46-i46
Industry develops increasingly complex and advanced materials while incorporating the Safe-by-Design (SbD) concept into the R&D goals. Within HARMLESS (EU H2020), we use concepts of similarity for the risk screening during the SbD iterations. We rely
Autor:
Johannes G. Keller, Michael Persson, Philipp Müller, Lan Ma-Hock, Kai Werle, Josje Arts, Robert Landsiedel, Wendel Wohlleben
Publikováno v:
NanoImpact. 29:100455
Autor:
Oliver Hachmöller, Ursula G. Sauer, Sabine Hirth, Hubert Waindok, Kai Werle, Wendel Wohlleben
Publikováno v:
Chemical research in toxicology. 34(3)
The hazard potential, including carcinogenicity, of inhaled man-made vitreous fibers (MMVFs) is correlated with their biodurability in the lung, as prerequisite for biopersistence. Abiotic dissolution testing serves to predict biodurability. We re-an
Autor:
Lan Ma-Hock, Michael Persson, Wendel Wohlleben, Robert Landsiedel, Josje H.E. Arts, Johannes Keller, Philipp Müller, Kai Werle
Publikováno v:
NanoImpact
Different nanoforms (NF) of the same substance each need to be registered under REACH, but similarities in physiological interaction -among them biodissolution- can justify read-across within a group of NFs, thereby reducing the need to perform anima
Autor:
Kai Werle, Sabine Hirth, Oliver Hachmöller, Wendel Wohlleben, Hubert Waindok, Ursula G. Sauer
Publikováno v:
Chemical Research in Toxicology. 34:1697-1698
Autor:
Johannes G, Keller, Daniel F, Quevedo, Lara, Faccani, Anna L, Costa, Robert, Landsiedel, Kai, Werle, Wendel, Wohlleben
Publikováno v:
Nanotoxicology. 15(1)
Dose-response by
Autor:
Willie J.G.M. Peijnenburg, Emmanuel Ruggiero, Kai Werle, Wendel Wohlleben, Vicki Stone, Matthew S. P. Boyles, Derek A. Elam, Fiona Murphy
Publikováno v:
Materials, Vol 13, Iss 2235, p 2235 (2020)
Materials
Materials
The reactivity of particle surfaces can be used as a criterion to group nanoforms (NFs) based on similar potential hazard. Since NFs may partially or completely dissolve over the duration of the assays, with the ions themselves inducing a response, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2436f19b1d2b04a51b77941ac5a7df2f
http://hdl.handle.net/10029/623807
http://hdl.handle.net/10029/623807