Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kai Wen Ho"'
Autor:
Huei-Jen Chen, Yi-An Cheng, Yu-Tung Chen, Chia-Ching Li, Bo-Cheng Huang, Shih-Ting Hong, I.-Ju Chen, Kai-Wen Ho, Chiao-Yun Chen, Fang-Ming Chen, Jaw-Yuan Wang, Steve R. Rofer, Tian-Lu Cheng, Tung-Ho Wu
Publikováno v:
Cancer Nanotechnology, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/2b4dfddba7b744d18fb782d6aef7decf
Autor:
Huei-Jen Chen, Yi-An Cheng, Yu-Tung Chen, Chia-Ching Li, Bo-Cheng Huang, Shih-Ting Hong, I.-Ju Chen, Kai-Wen Ho, Chiao-Yun Chen, Fang-Ming Chen, Jaw-Yuan Wang, Steve R. Roffler, Tian-Lu Cheng, Tung-Ho Wu
Publikováno v:
Cancer Nanotechnology, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Background PEGylated nanoparticles (PEG-NPs) are not effective for hematologic malignancies as they lack the enhanced permeability and retention effect (EPR effect). Tumor-targeted PEG-NPs can systemically track lymphoma and actively interna
Externí odkaz:
https://doaj.org/article/d7e948b59260455786e1f5ea63ad1238
Autor:
Yuan-Chin Hsieh, Jun-min Liao, Kuo-Hsiang Chuang, Kai-Wen Ho, Shih-Ting Hong, Hui-Ju Liu, Bo-Cheng Huang, I-Ju Chen, Yen-Ling Liu, Jaw-Yuan Wang, Hsiang-Lin Tsai, Yu-Cheng Su, Yen-Tseng Wang, Tian-Lu Cheng
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Humanization of mouse monoclonal antibodies (mAbs) is crucial for reducing their immunogenicity in humans. However, humanized mAbs often lose their binding affinities. Therefore, an in silico humanization method that can prevent t
Externí odkaz:
https://doaj.org/article/682be9e061ff404fb8b92628dae0d0c1
Autor:
Wen-Wei Lin, Yun-Chi Lu, Bo-Cheng Huang, Chih-Hung Chuang, Yi-An Cheng, I.-Ju Chen, Hui-Ju Liu, Kai-Wen Ho, Tzu-Yi Liao, En-Shuo Liu, Ting-Yi Wu, Long-Sen Chang, Shih-Ting Hong, Tian-Lu Cheng
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Canakinumab is a fully human monoclonal antibody that specifically neutralizes human interleukin (IL)-1β and has been approved by the US Food and Drug Administration for treating different types of autoinflammatory disorders such as cryopyr
Externí odkaz:
https://doaj.org/article/cbc2120056d34be588820d88d63a8a3e
Autor:
Wen-Wei Lin, Yi-An Cheng, Chia-Ching Li, Kai-Wen Ho, Huei-Jen Chen, I.-J.u Chen, Bo-Cheng Huang, Hui-Ju Liu, Yun-Chi Lu, Chiu-Min Cheng, Ming-Yii Huang, Hung-Wen Lai, Tian-Lu Cheng
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Ovarian cancer is highly metastatic, with a high frequency of relapse, and is the most fatal gynecologic malignancy in women worldwide. It is important to elevate the drug susceptibility and cytotoxicity of ovarian cancer cells, thereby elim
Externí odkaz:
https://doaj.org/article/63d97e87db234af79d3c1e4526c6bbd3
Autor:
Kai-Wen Ho, I.-J.u Chen, Yi-An Cheng, Tzu-Yi Liao, En-Shuo Liu, Huei-Jen Chen, Yun-Chi Lu, Yu-Cheng Su, Steve R. Roffler, Bo-Cheng Huang, Hui-Ju Liu, Ming-Yii Huang, Chiao-Yun Chen, Tian-Lu Cheng
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background Tumor-targeted nanoparticles hold great promise as new tools for therapy of liquid cancers. Furthermore, the therapeutic efficacy of nanoparticles can be improved by enhancing the cancer cellular internalization. Methods In this s
Externí odkaz:
https://doaj.org/article/90203a981820425d90aa6193a4e80d5c
Autor:
Kai-Wen Cheng, Chih-Hua Tseng, I.-Ju Chen, Bo-Cheng Huang, Hui-Ju Liu, Kai-Wen Ho, Wen-Wei Lin, Chih-Hung Chuang, Ming-Yii Huang, Yu-Lin Leu, Steve R. Roffler, Jaw-Yuan Wang, Yeh-Long Chen, Tian-Lu Cheng
Publikováno v:
Pharmacological Research, Vol 177, Iss , Pp 106115- (2022)
The bidirectional interaction between carcinogens and gut microbiota that contributes to colorectal cancer is complicated. Reactivation of carcinogen metabolites by microbial β-glucuronidase (βG) in the gut potentially plays an important role in co
Externí odkaz:
https://doaj.org/article/55f73cca8fc546a79e2f4bf887feeae5
Autor:
Wen-Wei Lin, Kai-Wen Ho, Hsiang-Han Su, Tien-Fang Fang, Shey-Cherng Tzou, I-Ju Chen, Yun-Chi Lu, Mu-Shen Chang, Yun-Chen Tsai, En-Shuo Liu, Yu-Cheng Su, Yen-Tseng Wang, Tian-Lu Cheng, Hsin-Kai Huang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Fibrinogen-like protein 1 (FGL1) was recently identified as a major ligand of lymphocyte-activation gene-3 (LAG-3) on activated T cells and serves as an immune suppressive molecule for regulation of immune homeostasis. However, whether FGL1 has thera
Externí odkaz:
https://doaj.org/article/2f22afbac68e419987c354eef80b6a3e
Autor:
Chia-Ching Li, Chiu-Min Cheng, Yun-Chi Lu, Hung-Wen Lai, Kai-Wen Ho, I-Ju Chen, Yi-An Cheng, Ming-Yii Huang, Huei-Jen Chen, Hui-Ju Liu, Bo-Cheng Huang, Wen-Wei Lin, Tian-Lu Cheng
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Ovarian cancer is highly metastatic, with a high frequency of relapse, and is the most fatal gynecologic malignancy in women worldwide. It is important to elevate the drug susceptibility and cytotoxicity of ovarian cancer cells, thereby eliminating r
Autor:
Tian-Lu Cheng, I-Ju Chen, Yun Chi Lu, Yu-Cheng Su, Tzu Yi Liao, Yi An Cheng, Ming-Yii Huang, Kai Wen Ho, Steve R. Roffler, Huei Jen Chen, En Shuo Liu, Chiao Yun Chen, Hui Ju Liu, Bo Cheng Huang
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-12 (2021)
Journal of Nanobiotechnology
Journal of Nanobiotechnology
Background Tumor-targeted nanoparticles hold great promise as new tools for therapy of liquid cancers. Furthermore, the therapeutic efficacy of nanoparticles can be improved by enhancing the cancer cellular internalization. Methods In this study, we