Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kai Walstein"'
Autor:
Linda E. Cox, Kai Walstein, Lena Völlger, Friederike Reuner, Alexandra Bick, Annika Dötsch, Andrea Engler, Jürgen Peters, Maren von Köckritz-Blickwede, Simon T. Schäfer
Publikováno v:
BMC Anesthesiology, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background There is little knowledge, whether in patients with sepsis neutrophil extracellular trap (NET) formation and NET degrading nuclease activity are altered. Thus, we tested the hypotheses that 1) NET formation from neutrophils of sep
Externí odkaz:
https://doaj.org/article/a9e95e84342c4822aab23297fcb152e2
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
The CENP-A chaperone HJURP associates with Mis18α, Mis18β, and M18BP1 to target centromeres and deposit new CENP-A. Here the authors provide evidence that two repeats in human HJURP previously proposed to be functionally distinct are interchangeabl
Externí odkaz:
https://doaj.org/article/d54c0ddeaf074c26b0658f60a5479d52
Autor:
Dongqing Pan, Kerstin Klare, Arsen Petrovic, Annika Take, Kai Walstein, Priyanka Singh, Arnaud Rondelet, Alexander W Bird, Andrea Musacchio
Publikováno v:
eLife, Vol 6 (2017)
Centromeres are unique chromosomal loci that promote the assembly of kinetochores, macromolecular complexes that bind spindle microtubules during mitosis. In most organisms, centromeres lack defined genetic features. Rather, they are specified epigen
Externí odkaz:
https://doaj.org/article/a9e0a35e106a4e21ab076ff119ea257d
Autor:
Annika Dötsch, Lewin Eisele, Miriam Rabeling, Katharina Rump, Kai Walstein, Alexandra Bick, Linda Cox, Andrea Engler, Hagen S. Bachmann, Karl-Heinz Jöckel, Michael Adamzik, Jürgen Peters, Simon T. Schäfer
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 6, p 1266 (2017)
Hypoxia-inducible-factor-2α (HIF-2α) and HIF-2 degrading prolyl-hydroxylases (PHD) are key regulators of adaptive hypoxic responses i.e., in acute respiratory distress syndrome (ARDS). Specifically, functionally active genetic variants of HIF-2α (
Externí odkaz:
https://doaj.org/article/c6f56ba284b6408aba452c95397398dc
Autor:
Marion E. Pesenti, Tobias Raisch, Duccio Conti, Kai Walstein, Ingrid Hoffmann, Dorothee Vogt, Daniel Prumbaum, Ingrid R. Vetter, Stefan Raunser, Andrea Musacchio
Publikováno v:
Molecular cell. 82(11)
Centromeres are specialized chromosome loci that seed the kinetochore, a large protein complex that effects chromosome segregation. A 16-subunit complex, the constitutive centromere associated network (CCAN), connects between the specialized centrome
Autor:
Dorothee Vogt, Andrea Musacchio, Ingrid R. Vetter, Kai Walstein, Birte Hagemeier, Arsen Petrovic, Dongqing Pan
Publikováno v:
Science Advances
Biochemical reconstitution of human kinetochore delivers complexes with all subunits in the expected stoichiometry.
Centromeres are epigenetically determined chromosomal loci that seed kinetochore assembly to promote chromosome segregation durin
Centromeres are epigenetically determined chromosomal loci that seed kinetochore assembly to promote chromosome segregation durin
Autor:
Ingrid R. Vetter, Andrea Musacchio, Kai Walstein, Birte Hagemeier, Arsen Petrovic, Dorothee Vogt, Dongqing Pan
Centromeres are epigenetically determined chromosomal loci that seed kinetochore assembly to promote chromosome segregation during cell division. CENP-A, a centromere-specific histone H3 variant, establishes the foundations for centromere epigenetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4061ec94a45228d3383852c4aa3e4808
https://doi.org/10.1101/2020.12.01.407130
https://doi.org/10.1101/2020.12.01.407130
Autor:
Linda Cox, Kai Walstein, Lena Völlger, Friederike Reuner, Alexandra Bick, Annika Dötsch, Andrea Engler, Jürgen Peters, Maren von Köckritz-Blickwede, Simon T. Schäfer
Publikováno v:
BMC Anesthesiology
BMC Anesthesiology, Vol 20, Iss 1, Pp 1-9 (2020)
BMC Anesthesiology, Vol 20, Iss 1, Pp 1-9 (2020)
Background: There is little knowledge, whether in patients with sepsis neutrophil extracellular trap (NET) formation and NET degrading nuclease activity are altered. Thus, we tested the hypotheses that 1) NET formation from neutrophils of septic pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed85df836e1b186271efa12abdb5475e
https://duepublico2.uni-due.de/receive/duepublico_mods_00071666
https://duepublico2.uni-due.de/receive/duepublico_mods_00071666
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Nucleosomes containing the histone H3 variant CENP-A are the epigenetic mark of centromeres, the kinetochore assembly sites required for chromosome segregation. HJURP is the CENP-A chaperone, which associates with Mis18α, Mis18β, and M18BP1 to targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00ca95231488a896b052e1dc7204c82
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85071896344
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85071896344
Autor:
Nathalie M. Malewicz, Astrid M. Westendorf, Monika Lindemann, Simon T. Schäfer, Kai Walstein, Jürgen Peters, Torsten Heine, Annika Dötsch, Peter A. Horn, Linda Cox, Andrea Engler, Alexandra Bick
Critically ill patients are at risk for sepsis, and immunosuppressive mechanisms may prevail. Whether functional tests are helpful to detect immune alterations is largely unknown. Therefore, we tested the hypotheses that reactivity of peripheral bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a098a2bf56cf0d1ba4c888aa232a682
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85075814242
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85075814242