Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Kai S Erdmann"'
Autor:
Christine M Tait, Kavitha Chinnaiya, Elizabeth Manning, Mariyam Murtaza, John-Paul Ashton, Nicholas Furley, Chris J Hill, C Henrique Alves, Jan Wijnholds, Kai S Erdmann, Andrew Furley, Penny Rashbass, Raman M Das, Kate G Storey, Marysia Placzek
Publikováno v:
PLoS Biology, Vol 18, Iss 3, p e3000470 (2020)
In the spinal cord, the central canal forms through a poorly understood process termed dorsal collapse that involves attrition and remodelling of pseudostratified ventricular layer (VL) cells. Here, we use mouse and chick models to show that dorsal v
Externí odkaz:
https://doaj.org/article/f8b3e06e128a4e3d929b8ac00ab8d735
Autor:
Markus Dicks, Gerd Kock, Bastian Kohl, Xueyin Zhong, Stefanie Pütz, Rolf Heumann, Kai S. Erdmann, Raphael Stoll
Publikováno v:
BMC Molecular and Cell Biology, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Protein tyrosine phosphatase PTPN13, also known as PTP-BL in mice, is a large multi-domain non-transmembrane scaffolding protein with a molecular mass of 270 kDa. It is involved in the regulation of several cellular processes such
Externí odkaz:
https://doaj.org/article/5b2a6bcbda254ecda2ff7021a1941f83
Autor:
Elena Naumovska, Germaine Aalderink, Christian Wong Valencia, Kinga Kosim, Arnaud Nicolas, Stephen Brown, Paul Vulto, Kai S. Erdmann, Dorota Kurek
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 4964 (2020)
Intestinal organoids have emerged as the new paradigm for modelling the healthy and diseased intestine with patient-relevant properties. In this study, we show directed differentiation of induced pluripotent stem cells towards intestinal-like phenoty
Externí odkaz:
https://doaj.org/article/1ea9d809a892451f9e03eb03a91af37f
Autor:
Auste Kanapeckaite, Claudia Beaurivage, Kai S. Erdmann, Cindy Loomans, Richard Antonius Jozef Janssen, Jan Stallen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports
Inflammatory bowel disease (IBD) is a complex multi-factorial disease for which physiologically relevant in vitro models are lacking. Existing models are often a compromise between biological relevance and scalability. Here, we integrated intestinal
Autor:
Maté Ongenaert, Elizabeth Smythe, Richard A.J. Janssen, Henriëtte L. Lanz, Andrew R. Wood, Jan Stallen, Edo D. Elstak, Kai S. Erdmann, Sindhu Naik, Paniz Saidiyan
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5361, p 5361 (2021)
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5361, p 5361 (2021)
Lowe syndrome and Dent II disease are X-linked monogenetic diseases characterised by a renal reabsorption defect in the proximal tubules and caused by mutations in the OCRL gene, which codes for an inositol-5-phosphatase. The life expectancy of patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a74c7147185d794d1909aada6e0337
https://eprints.whiterose.ac.uk/174740/1/ijms-22-05361-v2.pdf
https://eprints.whiterose.ac.uk/174740/1/ijms-22-05361-v2.pdf
Autor:
Elizabeth M. Manning, John-Paul Ashton, C. Henrique Alves, Jan Wijnholds, Mariyam Murtaza, Marysia Placzek, Andrew J.W. Furley, Kai S. Erdmann, Christopher J. Hill, Raman M. Das, P. Rashbass, Kavitha Chinnaiya, Nicholas Furley, Kate G. Storey, Christine M. Tait
Publikováno v:
PLoS Biology, Vol 18, Iss 3, p e3000470 (2020)
Tait, C M, Chinnaiya, K, Manning, E, Murtaza, M, Ashton, J-P, Furley, N, Hill, C J, Alves, C H, Wijnholds, J, Erdmann, K S, Furley, A, Rashbass, P, Das, R M, Storey, K G & Placzek, M 2020, ' Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal ', PLoS Biology, vol. 18, no. 3, pp. e3000470 . https://doi.org/10.1371/journal.pbio.3000470
PLoS Biology, 18(3). PUBLIC LIBRARY SCIENCE
PLoS Biology, 18(3). Public Library of Science
PLoS Biology
Tait, C M, Chinnaiya, K, Manning, E, Murtaza, M, Ashton, J-P, Furley, N, Hill, C J, Alves, C H, Wijnholds, J, Erdmann, K S, Furley, A, Rashbass, P, Das, R M, Storey, K G & Placzek, M 2020, ' Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal ', PLoS Biology, vol. 18, no. 3, pp. e3000470 . https://doi.org/10.1371/journal.pbio.3000470
PLoS Biology, 18(3). PUBLIC LIBRARY SCIENCE
PLoS Biology, 18(3). Public Library of Science
PLoS Biology
In the spinal cord, the central canal forms through a poorly understood process termed dorsal collapse that involves attrition and remodelling of pseudostratified ventricular layer (VL) cells. Here, we use mouse and chick models to show that dorsal v
Autor:
Gerd Kock, Markus Dicks, King Tuo Yip, Bastian Kohl, Stefanie Pütz, Rolf Heumann, Kai S. Erdmann, Raphael Stoll
Protein tyrosine phosphatase PTPN13, also known as PTP-BL in mice, represents a large multi-domain non-transmembrane scaffolding protein that contains five consecutive PDZ domains. Here, we report the solution structures of the extended murine PTPN13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d464796e08238b8d0336deaebd6c35
Autor:
Arnaud Nicolas, Germaine Aalderink, Elena Naumovska, Stephen Brown, Kinga Kosim, Dorota Kurek, Paul Vulto, Kai S. Erdmann, Christian Wong Valencia
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4964, p 4964 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 14
International Journal of Molecular Sciences
Volume 21
Issue 14
Intestinal organoids have emerged as the new paradigm for modelling the healthy and diseased intestine with patient-relevant properties. In this study, we show directed differentiation of induced pluripotent stem cells towards intestinal-like phenoty
Autor:
Fangyan Yu, Mark O. Collins, Kai S. Erdmann, Claire M. Murzeau, Pei-Li Tseng, Shruti Sharma, Antonio Carmona, Sindhu Naik, Agnieszka Skowronek
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Fas plays a major role in regulating ligand-induced apoptosis in many cell types. It is well known that several cancers demonstrate reduced cell surface levels of Fas and thus escape a potential control system via ligand-induced apoptosis, although u
Publikováno v:
Scientific Reports
A primary cilium is present on most eukaryotic cells and represents a specialized organelle dedicated to signal transduction and mechanosensing. Defects in cilia function are the cause for several human diseases called ciliopathies. The serologically