The Course of Disease in Major Depressive Disorder Is Associated With Altered Activity of the Limbic System During Negative Emotion Processing

Autor: Ronny Redlich, Katharina Dohm, Tim Hahn, Udo Dannlowski, Stefanie Probst, Axel Krug, Elisabeth J. Leehr, Igor Nenadic, Lena Waltemate, Tina Meller, Dominik Grotegerd, Kai Ringwald, Simon Schmitt, Jonathan Repple, Fabian Breuer, Katharina Brosch, Frederike Stein, Carina Hülsmann, Tilo Kircher, Julia-Katharina Pfarr, Susanne Meinert, Katharina Thiel, Andreas Jansen, Janik Goltermann, Nils Opel, Melissa Klug, Antonia Warneke, Hannah Lemke, Verena Enneking, Alexandra Winter

Publikováno v: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 7:323-332

Background Brain functional alterations during emotion processing in patients with major depressive disorder (MDD) compared with healthy control subjects (HCs) are frequently reported. However, evidence for functional correlates of emotion processing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc23cdb69125dea4a1fe80bd46c8a42e
https://doi.org/10.1016/j.bpsc.2021.05.008

Genetic risk for psychiatric illness is associated with the number of hospitalizations of bipolar disorder patients

Autor: Markus M. Nöthen, Marcella Rietschel, Stefanie Heilmann-Heimbach, Fabian Streit, Niamh Mullins, Katrin Gade, Frederike Stein, Urs Heilbronner, Maria Grigoroiu-Serbanescu, Dominik Grotegerd, Daniela Reich-Erkelenz, Monika Budde, Julia-Katharina Pfarr, Kristina Adorjan, Janos Kalman, Ashley L. Comes, Mojtaba Oraki Kohshour, Sergi Papiol, Fanny Senner, Farah Klöhn-Saghatolislam, Thomas G. Schulze, Udo Dannlowski, Susanne Meinert, Tim Hahn, Igor Nenadic, Katharina Brosch, Tilo Kircher, Till F. M. Andlauer, Tina Meller, Kai Ringwald, Sabrina K. Schaupp, Andreas J. Forstner, Eva C. Schulte, Heike Anderson-Schmidt, Thomas J. Vogl, Peter Falkai, Maria Heilbronner

Publikováno v: Journal of affective disorders 296, 532-540 (2022). doi:10.1016/j.jad.2021.09.073

Objectives Bipolar disorder (BD) has a highly heterogeneous clinical course that is characterized by relapses and increased health care utilization in a significant fraction of patients. A thorough understanding of factors influencing illness course

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5024e363a78d7dd789c6a5486f7a1a
https://doi.org/10.1016/j.jad.2021.09.073

Association of brain white matter microstructure with cognitive performance in major depressive disorder and healthy controls: a diffusion-tensor imaging study

Autor: Lena Waltemate, Tina Meller, Kai Ringwald, Nils R. Winter, Marius Gruber, Udo Dannlowski, Jonathan Repple, Olaf Steinsträter, Simon Schmitt, Ricarda Ines Schubotz, Dominik Grotegerd, Susanne Meinert, Tim Hahn, Verena Enneking, Frederike Stein, Nils Opel, Julia-Katharina Pfarr, Katharina Thiel, Hannah Lemke, Axel Krug, Isabel Abheiden, Igor Nenadic, Katharina Brosch, Tilo Kircher, Nico Nowack, Alexandra Winter, Elisabeth J. Leehr, Katharina Dohm

Publikováno v: Molecular Psychiatry. 27:1103-1110

Cognitive deficits are central attendant symptoms of major depressive disorder (MDD) with a crucial impact in patients’ everyday life. Thus, it is of particular clinical importance to understand their pathophysiology. The aim of this study was to i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1689096cce76064f9222e23f69e49ee1
https://doi.org/10.1038/s41380-021-01330-8

Longitudinal structural brain changes in bipolar disorder: A multicenter neuroimaging study of 1232 individuals by the ENIGMA Bipolar Disorder Working Group

Autor: Theophilus N. Akudjedu, Frederike Stein, Edith Pomarol-Clotet, Lars T. Westlye, Ulrik Fredrik Malt, Erlend Bøen, Fabian Breuer, Chao Suo, Tina Meller, Tim Hahn, Francesco Benedetti, Jose Manuel Goikolea, Silvia Alonso-Lana, Adam George White, Dag Alnæs, Julia-Katharina Pfarr, Beathe Haatveit, Sara Poletti, Kai Ringwald, Nathalia Zak, Benny Liberg, Kelvin Sarink, Giulia Tronchin, Yann Chye, Janice M. Fullerton, Orwa Dandash, Igor Nenadic, Caterina del Mar Bonnín, Elisa M T Melloni, Udo Dannlowski, Michael Berk, Dominik Grotegerd, Christopher R.K. Ching, Lukas Fisch, Torbjørn Elvsåshagen, Andreas Dahl, Martin Alda, Francesco Panicalli, Ingrid Agartz, Martin Ingvar, Bronwyn Overs, Joaquim Radua, Katharina Brosch, Alexander V. Lebedev, Kang Sim, Tilo Kircher, Leila Nabulsi, Dara M. Cannon, Erick J. Canales-Rodríguez, Paul M. Thompson, Nils Opel, Jonathan Repple, R. Salvador, Katharina Dohm, Philip B. Mitchell, Colm McDonald, Salvador Sarró, Rachel M. Brouwer, Ole A. Andreassen, Tomas Hajek, Mikael Landén, Simon Schmitt, Sophia I. Thomopoulos, Elena Rodriguez-Cano, Eduard Vieta, Ingrid Melle, Rhoshel K. Lenroot, Lakshmi N. Yatham, Sean R. McWhinney, Gloria Roberts, Christoph Abé, Walter Heindel

Publikováno v: Biological psychiatry, 91(6), 582-592. Elsevier USA
ENIGMA Bipolar Disorder Working Group 2022, ' Longitudinal Structural Brain Changes in Bipolar Disorder: A Multicenter Neuroimaging Study of 1232 Individuals by the ENIGMA Bipolar Disorder Working Group ', Biological psychiatry, vol. 91, no. 6, pp. 582-592 . https://doi.org/10.1016/j.biopsych.2021.09.008

Background: Bipolar disorder (BD) is associated with cortical and subcortical structural brain abnormalities. It is unclear whether such alterations progressively change over time, and how this is related to the number of mood episodes. To address th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff961a7a26551ecf478f6404d6d5225
https://eprints.bournemouth.ac.uk/36033/14/PIIS0006322321015973.pdf

Structural brain alterations associated with suicidal thoughts and behaviors in young people: results across 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium

Autor: Benson Mwangi, Sonia Ambrogi, Lianne Schmaal, Frederike Stein, Nic J.A. van der Wee, Mon-Ju Wu, Amar Ojha, Susanne Meinert, Frank Iorfino, Julia-Katharina Pfarr, Karina S. Blair, Melissa Klug, Igor Nenadic, Robert James R. Blair, Katie A. McLaughlin, Robert Vermeiren, Margaret A. Sheridan, Elizabeth Lippard, Elisabeth J. Leehr, Ben J. Harrison, Adrian I. Campos, Andreas Jansen, Bonnie Klimes-Dougan, Alexandra Winter, Hilary P. Blumberg, Joanna Bright, Steven J.A. van der Werff, Dominik Grotegerd, Marsal Sanches, Janice M. Fullerton, Diana Tordesillas-Gutiérrez, L Colic, Christopher G. Davey, Bronwyn Overs, Georg Romer, Jochen Bauer, Jair C. Soares, Yara J. Toenders, Baptiste Couvy-Duchesne, Katharina Brosch, Neda Jahanshad, Lauren E. Salminen, Yuqi Cheng, Laura S van Velzen, Benedicto Crespo-Facorro, Emmanuelle Corruble, Gloria Roberts, Tony T. Yang, Ian B. Hickie, Miguel E. Rentería, Adam Bryant Miller, Colm G. Connolly, Romain Colle, Tilo Kircher, Hannah S. Savage, Fabrice Jollant, Luca M. Villa, Rosa Ayesa-Arriola, Ian H. Gotlib, Udo Dannlowski, Ali Saffet Gonul, Anne-Laura van Harmelen, Zeynep Başgöze, Alyssa H. Zhu, Katharina Dohm, Philip B. Mitchell, Tiffany C. Ho, Gianfranco Spalletta, Fabrizio Piras, Tim Hahn, Mengxin He, Kai Ringwald, Paul M. Thompson, Aslihan Uyar-Demir, Giana I. Teresi, Kathryn R. Cullen, Nerisa Banaj, Maria R. Dauvermann

ObjectiveIdentifying brain differences associated with suicidal thoughts and behaviors (STBs) in young people is critical to understanding their development and generating effective approaches to early intervention and prevention. The ENIGMA Suicidal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c4d023b7925d8280b8d3851a2af9fa7
https://doi.org/10.1101/2021.09.27.21264068