Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kai Oliver Böker"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
BackgroundGotfried positive reduction offers an alternative strategy for femoral neck fracture (FNF) when achieving anatomical reduction is challenging. However, the biomechanical consequences of positive reduction remain unclear. The purpose of this
Externí odkaz:
https://doaj.org/article/17f96979bb8f4b63a138e5b451d79808
Autor:
Kai Oliver Böker, Linda Gätjen, Christopher Dölle, Katarina Vasic, Shahed Taheri, Wolfgang Lehmann, Arndt Friedrich Schilling
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11608 (2023)
Most implants used in trauma surgery are made of steel and remain inside the body only temporarily. The strong tissue interaction of such implants sometimes creates problems with their explantation. Modified implant surfaces, which decrease tissue at
Externí odkaz:
https://doaj.org/article/88a4064e5d7c43c98bd1610be6e08665
Publikováno v:
Life, Vol 12, Iss 4, p 496 (2022)
Seventy million patients worldwide are suffering from epilepsy. The long-term use of antiepileptic drugs causes the alteration of the bone tissue and its metabolism, thus increasing the risk of fractures. Clinical and pre-clinical studies have highli
Externí odkaz:
https://doaj.org/article/f875b04b015e4b8cbbb08a85cc0f824e
Autor:
Aline Jatho, Anke Zieseniss, Katja Brechtel-Curth, Jia Guo, Kai Oliver Böker, Gabriela Salinas, Roland H. Wenger, Dörthe M. Katschinski
Publikováno v:
Cells, Vol 11, Iss 4, p 753 (2022)
Inhibition of the prolyl-4-hydroxylase domain (PHD) enzymes, leading to the stabilization of hypoxia-inducible factor (HIF) α as well as to the stimulation of erythropoietin (Epo) synthesis, is the functional mechanism of the new anti-anemia drug ro
Externí odkaz:
https://doaj.org/article/424aef703446484f8917f85d6a28e77b
Autor:
Lara Timantra Schiller, Nicolás Lemus-Diaz, Rafael Rinaldi Ferreira, Kai Oliver Böker, Jens Gruber
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 9, Iss , Pp 278-287 (2018)
Research on cell-free vesicles revealed a multitude of characteristics, in particular of microvesicles and exosomes, that range from their potential as biomarkers to a function in horizontal transfer of genetic information from cell to cell and also
Externí odkaz:
https://doaj.org/article/daa402c36ffc42858b330662e25c760d
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13282 (2021)
MicroRNAs (miRNAs) can be transported in extracellular vesicles (EVs) and are qualified as possible messengers for cell–cell communication. In the context of osteoarthritis (OA), miR-221-3p has been shown to have a mechanosensitive and a paracrine
Externí odkaz:
https://doaj.org/article/e53e27bbb8634a06b271b970f8d847ae
Autor:
Xiaobin Shang, Kai Oliver Böker, Shahed Taheri, Thelonius Hawellek, Wolfgang Lehmann, Arndt F. Schilling
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9887 (2021)
Osteoarthritis (OA) is a chronic disease affecting the whole joint, which still lacks a disease-modifying treatment. This suggests an incomplete understanding of underlying molecular mechanisms. The Wnt/β-catenin pathway is involved in different pat
Externí odkaz:
https://doaj.org/article/3a9c4468f61f4218bfd3d3feb2905bdd
Autor:
Kai Oliver Böker, Frederick Kleinwort, Jan-Hendrick Klein-Wiele, Peter Simon, Katharina Jäckle, Shahed Taheri, Wolfgang Lehmann, Arndt F. Schilling
Publikováno v:
Materials, Vol 13, Iss 16, p 3526 (2020)
Metal implants used in trauma surgeries are sometimes difficult to remove after the completion of the healing process due to the strong integration with the bone tissue. Periodic surface micro- and nanostructures can directly influence cell adhesion
Externí odkaz:
https://doaj.org/article/43304acb7f934ec398d364538650da79
Publikováno v:
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13282
MicroRNAs (miRNAs) can be transported in extracellular vesicles (EVs) and are qualified as possible messengers for cell–cell communication. In the context of osteoarthritis (OA), miR-221-3p has been shown to have a mechanosensitive and a paracrine
Autor:
Doris Hendig, Cornelius Knabbe, Dagmar Akkermann, Kai Oliver Böker, Isabel Faust, Christina Eirich, Joachim Kuhn
Publikováno v:
Biochemical and biophysical research communications. 458(4)
The human isoenzymes xylosyltransferase-I and -II (XT-I, XT-II) catalyze the rate-limiting step in proteoglycan biosynthesis. Therefore, serum XT activity, mainly representing XT-II activity, displays a powerful biomarker to quantify the actual prote