Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Kai Ming Chou"'
Autor:
Wendi Zhou, Yih-wen Chen, Xiyong Liu, Peiguo Chu, Sofia Loria, Yafan Wang, Yun Yen, Kai-Ming Chou
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83978 (2013)
PURPOSE:The development of resistance against anticancer drugs has been a persistent clinical problem for the treatment of locally advanced malignancies in the head and neck mucosal derived squamous cell carcinoma (HNSCC). Recent evidence indicates t
Externí odkaz:
https://doaj.org/article/74e3a745d01742c8b54ccaae106701b1
Autor:
Kai-Ming Chou, Yung-Chi Cheng
Publikováno v:
Nature. 2/7/2002, Vol. 415 Issue 6872, p655. 5p. 4 Black and White Photographs, 5 Graphs.
Publikováno v:
Environmental and Molecular Mutagenesis. 57:322-330
Cancer and neurodegeneration represent the extreme responses of growing and terminally differentiated cells to cellular and genomic damage. The damage recognition mechanisms of nucleotide excision repair, epitomized by xeroderma pigmentosum (XP), and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a67868797c3e898401057f3d94b8495a
https://doi.org/10.1002/em.21995
https://doi.org/10.1002/em.21995
Autor:
Ka Wing Fong, Kai Ming Chou, Ingrid Revet, Raymond A. Swanson, Angela M. Brennan-Minnella, Vladimir Bezrookove, Yih Wen Chen, James E. Cleaver, Junjie Chen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 111, iss 37
Cockayne syndrome (CS) is a human DNA repair-deficient disease that involves transcription coupled repair (TCR), in which three gene products, Cockayne syndrome A (CSA), Cockayne syndrome B (CSB), and ultraviolet stimulated scaffold protein A (UVSSA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7551c16fec3fbe1a17459975d3eefea5
https://doi.org/10.1073/pnas.1414135111
https://doi.org/10.1073/pnas.1414135111
Autor:
Kai Ming Chou
Publikováno v:
Antioxidants & Redox Signaling. 14:2521-2529
The discovery of human DNA polymerase eta (pol η) has a major impact on the fields of DNA replication/repair fields. Since the discovery of human pol η, a number of new DNA polymerases with the ability to bypass various DNA lesions have been discov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b539f2feee230b9f0b6775b9d65ae826
https://doi.org/10.1089/ars.2010.3673
https://doi.org/10.1089/ars.2010.3673
Autor:
Richard E. Honkanen, Kai Ming Chou, Zafer Hatahet, Jang Yang Chang, Yun Yen, James E. Cleaver, Yih Wen Chen
Publikováno v:
Proceedings of the National Academy of Sciences. 105:16578-16583
Human DNA polymerase eta (pol eta) can replicate across UV-induced pyrimidine dimers, and defects in the gene encoding pol eta result in a syndrome called xeroderma pigmentosum variant (XP-V). XP-V patients are prone to the development of cancer in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19fcaf047ad2b580843f7318c8197677
https://doi.org/10.1073/pnas.0808589105
https://doi.org/10.1073/pnas.0808589105
Autor:
Her Shyong Shiah, Pao Chiung Hong, Jang Yang Chang, Wan Shu Lee, Shin-Hun Juang, Ching Jer Chang, Chia Chi Lung, Kai Ming Chou
Publikováno v:
Biochemical Pharmacology. 73:610-619
D-501036 [2,5-bis(5-hydroxymethyl-2-selenienyl)-3-hydroxymethyl-N-methylpyrrol], a novel selenophene derivative, is a highly potent cytotoxic agent with broad spectrum antitumor activity. The present study was undertaken to explore the mechanism(s) t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a5f0a3824185029fd93c8234986e4e
https://doi.org/10.1016/j.bcp.2006.10.019
https://doi.org/10.1016/j.bcp.2006.10.019
Autor:
Shin-Hun Juang, Ching Wei Huang, Hsu Pi Chen, Kai Ming Chou, Ching Jer Chang, Chia Chi Lung, Kuo Chu Fu, Leeyuan Huang, Ching Chuan Kuo, Yu Chin Wang, Cheng Li Hsu, Thomas C.K. Chan, Tom S. Chen, Jang Chang Chang, Curtis L. Ashendel, Kuo Shun Hsu, Shyh Fong Chen, Her Shyong Shiah, Li Yu Chen, Pao Chiung Hong, Meng Ju Lin
Publikováno v:
Molecular Cancer Therapeutics. 6:193-202
D-501036 [2,5-bis(5-hydroxymethyl-2-selenienyl)-3-hydroxymethyl-N-methylpyrrole] is herein identified as a novel antineoplastic agent with a broad spectrum of antitumoral activity against several human cancer cells and an IC50 value in the nanomolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b2065e5f2ad590acfb4fa053b0f8a2
https://doi.org/10.1158/1535-7163.mct-06-0482
https://doi.org/10.1158/1535-7163.mct-06-0482
Autor:
Angela M, Brennan-Minnella, Sarah T, Arron, Kai-Ming, Chou, Eric, Cunningham, James E, Cleaver
Publikováno v:
Environmental and molecular mutagenesis. 57(5)
Cancer and neurodegeneration represent the extreme responses of growing and terminally differentiated cells to cellular and genomic damage. The damage recognition mechanisms of nucleotide excision repair, epitomized by xeroderma pigmentosum (XP), and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::244683ed04282887bbd5b1d49fd36b67
https://pubmed.ncbi.nlm.nih.gov/27311994
https://pubmed.ncbi.nlm.nih.gov/27311994
Publikováno v:
Proceedings of the National Academy of Sciences. 112
Obesity and the metabolic syndrome have evolved to be major health issues throughout the world. Whether loss of genome integrity contributes to this epidemic is an open question. DNA polymerase η (pol η), encoded by the xeroderma pigmentosum (XP-V)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87711017589b8a46982e1fa88a19ff2d
https://doi.org/10.1073/pnas.1506954112
https://doi.org/10.1073/pnas.1506954112