Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kai Lovis"'
Autor:
Tobias Thaler, Elisabeth Kersten, Hannah JÖRIßEN, Chantal Fürstner, Sonja Anlauf, Mark Meininghaus, Kersten Matthias Gericke, Lisa Dietz, Dirk Schneider, Hartmut Beck, Virginia Marossek, Carsten Terjung, Johanna Anlahr, Daniel Meibom, Uwe Münster, Thomas Buyck, Raimund Kast, Kai Lovis, Timo Stellfeld, Guillaume Levilain, Michaela Bairlein, Clemens-Jeremias Von Bühler
Publikováno v:
Journal of Medicinal Chemistry. 63:11639-11662
Idiopathic pulmonary fibrosis (IPF) is a rare and devastating chronic lung disease of unknown etiology. Despite the approved treatment options nintedanib and pirfenidone, the medical need for a safe and well-tolerated antifibrotic treatment of IPF re
Autor:
Bastien O. Burek, Hong Thu Duong, Klaus Hochradel, Alexander Sutor, Matthias Rupp, Eike K. Heilmann, Kai Lovis, Jonathan Z. Bloh
Publikováno v:
European Journal of Organic Chemistry. 2022
Autor:
Alexander Sutor, Jonathan Z. Bloh, Bastien O. Burek, Klaus Hochradel, Hong Thu Duong, Kai Lovis, Eike Kevin Heilmann, Matthias Rupp
Publikováno v:
European Journal of Organic Chemistry. 2022
Autor:
Isabelle Grimm, Karl D. Collins, Tim Schulte, Gina Wycich, Lisa Candish, Simone T. Hauer, Kai Lovis
Publikováno v:
Organic Process Research & Development. 24:1185-1193
Herein we describe a straightforward approach for the scale-up of photoredox cross-coupling reactions from milligram to multigram scale using immersion-well batch reactors with minimal reoptimizati...
Autor:
Martin Radtke, Peter Kolkhof, Thomas Schwarz, Michael Gerisch, Kai Lovis, Dieter Lang, Anna Engelen, Johannes Platzek, Roland Heinig, G. Rohde
Publikováno v:
Drug Metabolism and Disposition. 46:1546-1555
Mass balance and biotransformation of finerenone, a nonsteroidal mineralocorticoid receptor antagonist, were investigated in four healthy male volunteers following a single oral administration of 10 mg (78 μCi) of [14C]finerenone and compared with d
Autor:
Sandra Hübner, Johannes Platzek, Jorma Hassfeld, Norbert Steinfeldt, Patrick Loos, Kai Lovis, Hannes Alex
Publikováno v:
Organic Process Research & Development. 20:452-464
The selective hydrogenation of functionalized nitroaromatics poses a major challenge from both academic as well as industrial viewpoints. As part of the CHEM21 initiative (www.chem21.eu), we are interested in highly selective, catalytic hydrogenation
Autor:
Kai Lovis, Ursula Bentrup, Sandra Hübner, Thomas Dietrich, Uwe Budde, Klaus Jähnisch, Lukas Küpper, Andreas Freitag
Publikováno v:
Organic Process Research & Development. 13:952-960
The advantages of microstructured reactors were utilized in a two-step process for the preparation of intermediates of vitamin D analogues, which are known to be important compounds in bone and min...
Publikováno v:
Organic Process Research & Development. 12:345-348
In this paper investigations for developing a continuous process for the fluorination of a steroid derivative with bis(methoxyethyl)-aminosulfurtrifluoride are presented. A kinetic model is suggested for this reaction. A simulation-based experimental
Publikováno v:
Macromolecular Chemistry and Physics. 197:303-313
The free-radical copolymerization of ethene and butyl acrylate was studied between 130 and 225°C at pressures from 1 500 to 2 500 bar. The reactions which were induced either thermally or laser-photochemically were run in two types of continuously o
Publikováno v:
Chemie Ingenieur Technik. 67:1652-1655
Miniaturisierte Apparaturen als Nachbildung kompletter Produktionsanlagen sind fur die Entwicklung neuer oder die Modifikationen bestehender Verfahren von besonderem Interesse. In dieser Arbeit soll eine Anlage vorgestellt werden, die es erlaubt, Hoc