Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Kai Kappert"'
Autor:
Eva Diehl-Wiesenecker, Noa Galtung, Johannes Dickescheid, Monika Prpic, Rajan Somasundaram, Kai Kappert, Wolfgang Bauer
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Early in the host-response to infection, neutrophils release calprotectin, triggering several immune signalling cascades. In acute infection management, identifying infected patients and stratifying these by risk of deterioration
Externí odkaz:
https://doaj.org/article/9c8163da0faf4fcf8ba8572f1fec8fe6
Autor:
Frederik Geisler, Lisa Haacke, Maren Lorenz, Eugen Schwabauer, Matthias Wendt, Lydia Bernhardt, Eman Dashti, Erik Freitag, Alexander Kunz, Christina Hofmann-Shen, Martina Zuber, Carolin Waldschmidt, Farid I. Kandil, Kai Kappert, Chantip Dang-Heine, Irina Lorenz-Meyer, Heinrich J. Audebert, Joachim E. Weber
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionIntravenous thrombolysis (IVT) and mechanical thrombectomy (MT) are well-established, evidence-based, time-critical therapies that reduce morbidity and mortality in acute ischemic stroke (AIS) patients. The exclusion of intracerebral hemo
Externí odkaz:
https://doaj.org/article/199a55c6ce3c491ba3075cb98a7eab6e
Autor:
Johannes Hartl, Florian Kurth, Kai Kappert, David Horst, Michael Mülleder, Gunther Hartmann, Markus Ralser
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 4, Pp n/a-n/a (2023)
The utilisation of protein biomarker panels, rather than individual protein biomarkers, offers a more comprehensive representation of human physiology. It thus has the potential to improve diagnosis, prognosis and the differentiation of responders fr
Externí odkaz:
https://doaj.org/article/d3978772ba524e9ea8b94021b7bbbfde
Autor:
Tatjana Schwarz, Pinkus Tober-Lau, David Hillus, Elisa T. Helbig, Lena J. Lippert, Charlotte Thibeault, Willi Koch, Irmgard Landgraf, Janine Michel, Leon Bergfeld, Daniela Niemeyer, Barbara Mühlemann, Claudia Conrad, Chantip Dang-Heine, Stefanie Kasper, Friederike Münn, Kai Kappert, Andreas Nitsche, Rudolf Tauber, Sein Schmidt, Piotr Kopankiewicz, Harald Bias, Joachim Seybold, Christof von Kalle, Terry C. Jones, Norbert Suttorp, Christian Drosten, Leif Erik Sander, Victor M. Corman, Florian Kurth
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 8, Pp 2174-2178 (2021)
We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in Germany. These data emphasize that nonpharmaceutical in
Externí odkaz:
https://doaj.org/article/af1f98e3745c4d0180f53051d86658b4
Autor:
Christian Schwedler, Marta Grzeski, Kai Kappert, Jörn Rust, Guido Heymann, Berthold Hoppe, Véronique Blanchard
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been affecting the world since January 2020 and has caused millions of deaths. To gain a better insight into molecular changes unde
Externí odkaz:
https://doaj.org/article/a8050f5f98c64b6f97d5ce58ddb9757d
Autor:
Robert Hauffe, Michaela Rath, Mareike Schell, Katrin Ritter, Kai Kappert, Stefanie Deubel, Christiane Ott, Markus Jähnert, Wenke Jonas, Annette Schürmann, André Kleinridders
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101276- (2021)
Objective: Insulin regulates mitochondrial function, thereby propagating an efficient metabolism. Conversely, diabetes and insulin resistance are linked to mitochondrial dysfunction with a decreased expression of the mitochondrial chaperone HSP60. Th
Externí odkaz:
https://doaj.org/article/8e70c968a1694ff39c2a66f6cc5ab0a2
Autor:
Bettina Greiner, Manuela Sommerfeld, Ulrich Kintscher, Thomas Unger, Kai Kappert, Elena Kaschina
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3271 (2022)
Cannabinoids (CB) are implicated in cardiovascular diseases via the two main receptor subtypes CB1R and CB2R. This study investigated whether cannabinoids regulate the activity of matrix metalloproteases (MMP-2, MMP-9) in vascular smooth muscle cells
Externí odkaz:
https://doaj.org/article/29b7ba1c843a40d5b7d2263122354b23
Autor:
Eva Schrezenmeier, Leon Bergfeld, David Hillus, Joerg-Detlev Lippert, Ulrike Weber, Pinkus Tober-Lau, Irmgard Landgraf, Tatjana Schwarz, Kai Kappert, Ana-Luisa Stefanski, Arne Sattler, Katja Kotsch, Thomas Dörner, Leif Erik Sander, Klemens Budde, Fabian Halleck, Florian Kurth, Victor Max Corman, Mira Choi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Patients with kidney failure have notoriously weak responses to common vaccines. Thus, immunogenicity of novel SARS-CoV-2 vaccines might be impaired in this group. To determine immunogenicity of SARS-CoV-2 vaccination in patients with chronic dialysi
Externí odkaz:
https://doaj.org/article/84ac61715746470ab45dcbe6bc547458
Autor:
Dijana Djureinovic, Victor Pontén, Per Landelius, Sahar Al Sayegh, Kai Kappert, Masood Kamali-Moghaddam, Patrick Micke, Elisabeth Ståhle
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background The overall prognosis of non-small cell lung cancer (NSCLC) is poor, and currently only patients with localized disease are potentially curable. Therefore, preferably non-invasively determined biomarkers that detect NSCLC patients
Externí odkaz:
https://doaj.org/article/2b37e0439d794044857b7c3cffa7fc1e
Autor:
Evren Caglayan, Manuela Trappiel, Arnica Behringer, Eva Maria Berghausen, Margarete Odenthal, Ernst Wellnhofer, Kai Kappert
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Background Obesity is associated with cardiovascular complications, including pulmonary hypertension (PH). Reports suggest that peroxisome proliferator-activated receptor-γ (PPARγ) has direct action in preventing vascular remodelling in PH
Externí odkaz:
https://doaj.org/article/b77e0ca4fa6b402384e3e08e489bb6e5