Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Kai Kammers"'
Autor:
Brooke Szczesny, Meher Preethi Boorgula, Sameer Chavan, Monica Campbell, Randi K. Johnson, Kai Kammers, Emma E. Thompson, Madison S. Cox, Gautam Shankar, Corey Cox, Andréanne Morin, Wendy Lorizio, Michelle Daya, Samir N. P. Kelada, Terri H. Beaty, Ayo P. Doumatey, Alvaro A. Cruz, Harold Watson, Edward T. Naureckas, B. Louise Giles, Ganiyu A. Arinola, Olumide Sogaolu, Adegoke G. Falade, Nadia N. Hansel, Ivana V. Yang, Christopher O. Olopade, Charles N. Rotimi, R. Clive Landis, Camila A. Figueiredo, Matthew C. Altman, Eimear Kenny, Ingo Ruczinski, Andrew H. Liu, Carole Ober, Margaret A. Taub, Kathleen C. Barnes, Rasika A. Mathias
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Asthma has striking disparities across ancestral groups, but the molecular underpinning of these differences is poorly understood and minimally studied. A goal of the Consortium on Asthma among African-ancestry Populations in the Americas (C
Externí odkaz:
https://doaj.org/article/db1254fb2cdc4e4c8565e2404e6adbdb
Autor:
Jan Haussmann, Wilfried Budach, Stefanie Corradini, David Krug, Danny Jazmati, Bálint Tamaskovics, Edwin Bölke, Alessia Pedotoa, Kai Kammers, Christiane Matuschek
Publikováno v:
Radiation Oncology, Vol 18, Iss 1, Pp 1-23 (2023)
Abstract Purpose/objective Adjuvant whole breast radiotherapy and systemic therapy are part of the current evidence-based treatment protocols for early breast cancer, after breast-conserving surgery. Numerous randomized trials have investigated the t
Externí odkaz:
https://doaj.org/article/05b780c67e3b44a38b46aea0c580629e
Autor:
Wendy Grant-McAuley, William Morgenlander, Sarah E. Hudelson, Manjusha Thakar, Estelle Piwowar-Manning, William Clarke, Autumn Breaud, Joel Blankson, Ethan Wilson, Helen Ayles, Peter Bock, Ayana Moore, Barry Kosloff, Kwame Shanaube, Sue-Ann Meehan, Anneen van Deventer, Sarah Fidler, Richard Hayes, Ingo Ruczinski, Kai Kammers, Oliver Laeyendecker, H. Benjamin Larman, Susan H. Eshleman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundHigh HIV viral load (VL) is associated with increased transmission risk and faster disease progression. HIV controllers achieve viral suppression without antiretroviral (ARV) treatment. We evaluated viremic control in a community-randomized
Externí odkaz:
https://doaj.org/article/3769d3f9e6b24fc1a64b70c5aea7e75e
Autor:
Marsha M. Wheeler, Adrienne M. Stilp, Shuquan Rao, Bjarni V. Halldórsson, Doruk Beyter, Jia Wen, Anna V. Mihkaylova, Caitlin P. McHugh, John Lane, Min-Zhi Jiang, Laura M. Raffield, Goo Jun, Fritz J. Sedlazeck, Ginger Metcalf, Yao Yao, Joshua B. Bis, Nathalie Chami, Paul S. de Vries, Pinkal Desai, James S. Floyd, Yan Gao, Kai Kammers, Wonji Kim, Jee-Young Moon, Aakrosh Ratan, Lisa R. Yanek, Laura Almasy, Lewis C. Becker, John Blangero, Michael H. Cho, Joanne E. Curran, Myriam Fornage, Robert C. Kaplan, Joshua P. Lewis, Ruth J. F. Loos, Braxton D. Mitchell, Alanna C. Morrison, Michael Preuss, Bruce M. Psaty, Stephen S. Rich, Jerome I. Rotter, Hua Tang, Russell P. Tracy, Eric Boerwinkle, Goncalo R. Abecasis, Thomas W. Blackwell, Albert V. Smith, Andrew D. Johnson, Rasika A. Mathias, Deborah A. Nickerson, Matthew P. Conomos, Yun Li, Unnur Þorsteinsdóttir, Magnús K. Magnússon, Kari Stefansson, Nathan D. Pankratz, Daniel E. Bauer, Paul L. Auer, Alex P. Reiner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Most genetic association studies have been done on single nucleotide polymorphisms and small indels, while other types of variants have been less studied. Here, the authors use whole genome sequencing in a diverse population to identify and provide e
Externí odkaz:
https://doaj.org/article/a133b13c75514301b2ec8c00097b28db
Autor:
Wendy Grant-McAuley, Oliver Laeyendecker, Daniel Monaco, Athena Chen, Sarah E. Hudelson, Ethan Klock, Ron Brookmeyer, Douglas Morrison, Estelle Piwowar-Manning, Charles S. Morrison, Richard Hayes, Helen Ayles, Peter Bock, Barry Kosloff, Kwame Shanaube, Nomtha Mandla, Anneen van Deventer, Ingo Ruczinski, Kai Kammers, H. Benjamin Larman, Susan H. Eshleman
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Multi-assay algorithms (MAAs) are used to estimate population-level HIV incidence and identify individuals with recent infection. Many MAAs use low viral load (VL) as a biomarker for long-term infection. This could impact incidenc
Externí odkaz:
https://doaj.org/article/d4fff91866cb44c7b477c8dbd3236eaa
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Phage ImmunoPrecipitation Sequencing (PhIP-Seq) is a recently developed technology to assess antibody reactivity, quantifying antibody binding towards hundreds of thousands of candidate epitopes. The output from PhIP-Seq experiments are read
Externí odkaz:
https://doaj.org/article/bb356b8b484440308eb60d7fcd974b11
Autor:
Ali R. Keramati, Ming-Huei Chen, Benjamin A. T. Rodriguez, Lisa R. Yanek, Arunoday Bhan, Brady J. Gaynor, Kathleen Ryan, Jennifer A. Brody, Xue Zhong, Qiang Wei, NHLBI Trans-Omics for Precision (TOPMed) Consortium, Kai Kammers, Kanika Kanchan, Kruthika Iyer, Madeline H. Kowalski, Achilleas N. Pitsillides, L. Adrienne Cupples, Bingshan Li, Thorsten M. Schlaeger, Alan R. Shuldiner, Jeffrey R. O’Connell, Ingo Ruczinski, Braxton D. Mitchell, Nauder Faraday, Margaret A. Taub, Lewis C. Becker, Joshua P. Lewis, Rasika A. Mathias, Andrew D. Johnson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Platelet aggregation is associated with myocardial infarction and stroke. Here, the authors have conducted a whole genome sequencing association study on platelet aggregation, discovering a locus in RGS18, where enhancer assays suggest an effect on a
Externí odkaz:
https://doaj.org/article/21f176ab19b541d294b9acdf21deb0ae
Autor:
Daniel R. Monaco, Sanjay V. Kottapalli, Florian P. Breitwieser, Danielle E. Anderson, Limin Wijaya, Kevin Tan, Wan Ni Chia, Kai Kammers, Patrizio Caturegli, Kathleen Waugh, Mario Roederer, Michelle Petri, Daniel W. Goldman, Marian Rewers, Lin-Fa Wang, H. Benjamin Larman
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103747- (2022)
Summary: Background: Comprehensive characterization of exposures and immune responses to viral infections is critical to a basic understanding of human health and disease. We previously developed the VirScan system, a programmable phage-display techn
Externí odkaz:
https://doaj.org/article/2cc445a3d2704ef8b00c16df22299c39
Autor:
Michael C. Schatz, Anthony A. Philippakis, Enis Afgan, Eric Banks, Vincent J. Carey, Robert J. Carroll, Alessandro Culotti, Kyle Ellrott, Jeremy Goecks, Robert L. Grossman, Ira M. Hall, Kasper D. Hansen, Jonathan Lawson, Jeffrey T. Leek, Anne O’Donnell Luria, Stephen Mosher, Martin Morgan, Anton Nekrutenko, Brian D. O’Connor, Kevin Osborn, Benedict Paten, Candace Patterson, Frederick J. Tan, Casey Overby Taylor, Jennifer Vessio, Levi Waldron, Ting Wang, Kristin Wuichet, Alexander Baumann, Andrew Rula, Anton Kovalsy, Clare Bernard, Derek Caetano-Anollés, Geraldine A. Van der Auwera, Justin Canas, Kaan Yuksel, Kate Herman, M. Morgan Taylor, Marianie Simeon, Michael Baumann, Qi Wang, Robert Title, Ruchi Munshi, Sushma Chaluvadi, Valerie Reeves, William Disman, Salin Thomas, Allie Hajian, Elizabeth Kiernan, Namrata Gupta, Trish Vosburg, Ludwig Geistlinger, Marcel Ramos, Sehyun Oh, Dave Rogers, Frances McDade, Mim Hastie, Nitesh Turaga, Alexander Ostrovsky, Alexandru Mahmoud, Dannon Baker, Dave Clements, Katherine E.L. Cox, Keith Suderman, Nataliya Kucher, Sergey Golitsynskiy, Samantha Zarate, Sarah J. Wheelan, Kai Kammers, Ana Stevens, Carolyn Hutter, Christopher Wellington, Elena M. Ghanaim, Ken L. Wiley, Jr., Shurjo K. Sen, Valentina Di Francesco, Deni s Yuen, Brian Walsh, Luke Sargent, Vahid Jalili, John Chilton, Lori Shepherd, B.J. Stubbs, Ash O’Farrell, Benton A. Vizzier, Jr., Charles Overbeck, Charles Reid, David Charles Steinberg, Elizabeth A. Sheets, Julian Lucas, Lon Blauvelt, Louise Cabansay, Noah Warren, Brian Hannafious, Tim Harris, Radhika Reddy, Eric Torstenson, M. Katie Banasiewicz, Haley J. Abel, Jason Walker
Publikováno v:
Cell Genomics, Vol 2, Iss 1, Pp 100085- (2022)
Summary: The NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-space (AnVIL; https://anvilproject.org) was developed to address a widespread community need for a unified computing environment for genomics data storage, managemen
Externí odkaz:
https://doaj.org/article/95ac1623e901491c821d128f529da364
Autor:
Kai Kammers, Athena Chen, Daniel R. Monaco, Sarah E. Hudelson, Wendy Grant-McAuley, Richard D. Moore, Galit Alter, Steven G. Deeks, Charles S. Morrison, Leigh A. Eller, Joel N. Blankson, Oliver Laeyendecker, Ingo Ruczinski, Susan H. Eshleman, H. Benjamin Larman
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IntroductionLow HIV viral load is associated with delayed disease progression and reduced HIV transmission. HIV controllers suppress viral load to low levels in the absence of antiretroviral treatment (ART). We used an antibody profiling system, VirS
Externí odkaz:
https://doaj.org/article/e4d57189af8a484ba845d1a29bae07de