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Autor:
Amanda M. D. Malone, Chi Hyun Kim, Kai Jair, Giri M. Shivaram, Joshua Rodriguez, Lidan You, Nikhil N. Batra, Christopher R. Jacobs, Ronald Y. Kwon
Publikováno v:
American journal of physiology. Cell physiology. 292(5)
Fluid flow due to loading in bone is a potent mechanical signal that may play an important role in bone adaptation to its mechanical environment. Previous in vitro studies of osteoblastic cells revealed that the upregulation of cyclooxygenase-2 (COX-