Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kai Hermanns"'
Publikováno v:
Expert Opinion on Pharmacotherapy. 16:457-464
Prolonged-release oxycodone/naloxone (OXN PR) showed improved gastrointestinal tolerability and equivalent analgesic efficacy compared to oxycodone alone in patients with non-cancer pain or cancer pain. This is the first dataset to demonstrate its ef
Autor:
Amy Pierce, John Langan, Kai Hermanns, John I. Wurzelmann, Christi S. Kleoudis, Daniel Lorch, Jerry Snidow, E. Mortensen, Ben Lasko, Jan-Peter Jansen
Publikováno v:
The Journal of Pain. 12:185-193
Gastrointestinal (GI) side effects are common with opioid medication, and constipation affects ∼40% of patients. Such symptoms considerably impair patients' quality of life. Alvimopan is an orally administered, systemically available, peripherally
Autor:
Karen Reimer, Petra Leyendecker, Dana Vondrackova, Winfried Meissner, Istvan Szombati, Susanne Weber, Kai Hermanns, Michael Hopp, Birgit Grothe, Christian Ruckes, Wolfgang Fleischer
Publikováno v:
The Journal of Pain. 9:1144-1154
This randomized, double-blind, placebo- and active-controlled, parallel-group study was designed to demonstrate the superiority of oxycodone in combination with naloxone in a prolonged release (PR) formulation over placebo with respect to analgesic e
Publikováno v:
Expert opinion on pharmacotherapy. 13(3)
Opioids have shown consistent efficacy in neuropathic pain, but opioid-induced bowel dysfunction is a relevant problem. In controlled clinical trials, a fixed-dose combination of prolonged-release (PR) oxycodone/PR naloxone was superior to oxycodone
Autor:
Michael Petraschka, Klaus-Dieter Wernecke, Claudia Spies, Stefanie Zenker, A. Reißhauer, Tanja Newie, Kai Hermanns, M. Schenk
Publikováno v:
The journal of pain. 7(6)
According to Prochaska’s transtheoretical model, the Freiburg Questionnaire stages of chronic pain management (FQ-STAPM) were used to classify chronic back patients into 4 distinct motivational stages. The FQ-STAMP was completed by 163 chronic back
Publikováno v:
Anesthesia and analgesia. 76(5)
A prospective, randomized, double-blind study investigating the efficacy of intranasal meperidine as compared with intravenous (i.v.) administration for postoperative pain relief is described. The study was limited to the initial titration of pain re