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of 8
pro vyhledávání: '"Kai Berkenfeld"'
Autor:
Ann-Cathrin Willmann, Kai Berkenfeld, Thilo Faber, Herbert Wachtel, Georg Boeck, Karl G. Wagner
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1528 (2022)
Nanocrystal suspensions proved to be a potent enabling principle for biopharmaceutics classification system class II drugs with dissolution limited bioavailability. In the example of itraconazole (ITZ) as a model drug combined with electrosteric stab
Externí odkaz:
https://doaj.org/article/289b207588534f169dfcc8136745e571
Autor:
Roman Groß, Kai Berkenfeld, Christoph Schulte, Anselm Ebert, Sunita Sule, Ameet Sule, Alf Lamprecht
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1185 (2022)
Commercially available dry powder inhalers (DPIs) are usually devices in a fixed combination with the intended formulation, and a change in medication by the physician often forces the patient to use a different device, requiring the patient to relea
Externí odkaz:
https://doaj.org/article/1a7858e9de714ac6968b55a8ae5f59be
Autor:
Roman Groß, Kai Berkenfeld, Christoph Schulte, Anselm Ebert, Sunita Sule, Ameet Sule, Alf Lamprecht
Publikováno v:
AAPS PharmSciTech. 23(7)
Pulmonary delivery systems should administer a high dose of the required formulation with the designated dry powder inhaler (DPI) to achieve therapeutic success. While the effects of device geometry and individual components used on powder dispersion
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 153:14-22
Tuberculosis is still one of the leading causes of death from a single infectious agent (i.e. Mycobacterium tuberculosis). First line therapy includes per oral administration of high doses of rifampicin over several months and is often times accompan
Publikováno v:
Expert Opinion on Drug Delivery. 17:305-322
Introduction: Recently, tuberculosis was reported as the leading cause of death from a single infectious agent. Standard therapy includes administration of four first-line antibiotics, i.e. rifampicin, isoniazid, ethambutol, and pyrazinamide over a p
Publikováno v:
International journal of pharmaceutics. 590
Rifampicin is an antibiotic used in tuberculosis therapy showing extensive (solvato-) polymorphism. Per oral administration of high doses is recommended, but application as dry powder for inhalation at the site of infection being the lungs, is desira
Publikováno v:
Molecular pharmaceutics. 17(5)
The induction port (IP) for aerosol analysis with the Next Generation Pharmaceutical Impactor as monographed in the United States and European pharmacopoeia (USPIP) lacks physiological relevance, which, amongst other reasons, has been identified as c
Publikováno v:
AAPS PharmSciTech. 16:479-490
Dry powder inhalers (DPIs) are an important and increasingly investigated method of modern therapy for a growing number of respiratory diseases. DPIs are a promising option for certain patient populations, and may help to overcome several limitations