Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Kai, Zinn"'
Publikováno v:
eLife, Vol 12 (2023)
Communication between distant cells can be mediated by extracellular vesicles (EVs) that deliver proteins and RNAs to recipient cells. Little is known about how EVs are targeted to specific cell types. Here, we identify the Drosophila cell-surface pr
Externí odkaz:
https://doaj.org/article/6ae530ebc5cc4e85be9bf6cb8744fc35
Autor:
Dirk H Siepe, Lukas T Henneberg, Steven C Wilson, Gaelen T Hess, Michael C Bassik, Kai Zinn, K Christopher Garcia
Publikováno v:
eLife, Vol 11 (2022)
Secreted proteins, which include cytokines, hormones, and growth factors, are extracellular ligands that control key signaling pathways mediating cell-cell communication within and between tissues and organs. Many drugs target secreted ligands and th
Externí odkaz:
https://doaj.org/article/90ea4d2824bf4511ac733cb205b973f5
Autor:
Shuwa Xu, Alina P. Sergeeva, Phinikoula S. Katsamba, Seetha Mannepalli, Fabiana Bahna, Jude Bimela, S. Lawrence Zipursky, Lawrence Shapiro, Barry Honig, Kai Zinn
Publikováno v:
Cell Reports, Vol 39, Iss 1, Pp 110618- (2022)
Summary: Neurons in the developing brain express many different cell adhesion molecules (CAMs) on their surfaces. CAM-binding affinities can vary by more than 200-fold, but the significance of these variations is unknown. Interactions between the imm
Externí odkaz:
https://doaj.org/article/f89dc971c1d84cf2a7121d9388e742ec
Publikováno v:
eLife, Vol 11 (2022)
Type IIa receptor-like protein tyrosine phosphatases (RPTPs) are essential for neural development. They have cell adhesion molecule (CAM)-like extracellular domains that interact with cell-surface ligands and coreceptors. We identified the immunoglob
Externí odkaz:
https://doaj.org/article/cada575edeb84de9a838f0145836b4e3
Autor:
Vasilios Tsarouhas, Dan Liu, Georgia Tsikala, Alina Fedoseienko, Kai Zinn, Ryo Matsuda, Daniel D. Billadeau, Christos Samakovlis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The regulation and coordination of F-actin networks are not well understood. Here, the authors show an antagonistic relationship between endosomal F-actin assembly and cortical bundle integrity during epithelial tube maturation that is regulated by k
Externí odkaz:
https://doaj.org/article/5be47f95eade47cbb57480612cb0e67d
Autor:
Savannah G Brovero, Julia C Fortier, Hongru Hu, Pamela C Lovejoy, Nicole R Newell, Colleen M Palmateer, Ruei-Ying Tzeng, Pei-Tseng Lee, Kai Zinn, Michelle N Arbeitman
Publikováno v:
eLife, Vol 10 (2021)
Drosophila reproductive behaviors are directed by fruitless neurons. A reanalysis of genomic studies shows that genes encoding dpr and DIP immunoglobulin superfamily (IgSF) members are expressed in fru P1 neurons. We find that each fru P1 and dpr/DIP
Externí odkaz:
https://doaj.org/article/03b6eb153b66416887a7a9e573608f2f
Identification and characterization of mushroom body neurons that regulate fat storage in Drosophila
Autor:
Bader Al-Anzi, Kai Zinn
Publikováno v:
Neural Development, Vol 13, Iss 1, Pp 1-13 (2018)
Abstract Background In an earlier study, we identified two neuronal populations, c673a and Fru-GAL4, that regulate fat storage in fruit flies. Both populations partially overlap with a structure in the insect brain known as the mushroom body (MB), wh
Externí odkaz:
https://doaj.org/article/46561b26b7eb422c80364f636daa178e
Publikováno v:
eLife, Vol 8 (2019)
Drosophila R7 UV photoreceptors (PRs) are divided into yellow (y) and pale (p) subtypes. yR7 PRs express the Dpr11 cell surface protein and are presynaptic to Dm8 amacrine neurons (yDm8) that express Dpr11’s binding partner DIP-γ, while pR7 PRs sy
Externí odkaz:
https://doaj.org/article/ed8d72ef2ec84fa7a4abec295af2a45f
Autor:
James Ashley, Violet Sorrentino, Meike Lobb-Rabe, Sonal Nagarkar-Jaiswal, Liming Tan, Shuwa Xu, Qi Xiao, Kai Zinn, Robert A Carrillo
Publikováno v:
eLife, Vol 8 (2019)
The Drosophila larval neuromuscular system provides an ideal context in which to study synaptic partner choice, because it contains a small number of pre- and postsynaptic cells connected in an invariant pattern. The discovery of interactions between
Externí odkaz:
https://doaj.org/article/6df7118dc7a14dcd9d8f2b74758845cb
Autor:
Dingbang Ma, Nicholas Herndon, Jasmine Quynh Le, Katharine C. Abruzzi, Kai Zinn, Michael Rosbash
Publikováno v:
Science Advances. 9
Our recent single-cell sequencing of most adult Drosophila circadian neurons indicated notable and unexpected heterogeneity. To address whether other populations are similar, we sequenced a large subset of adult brain dopaminergic neurons. Their gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::990a6d15aff109456b75b0e96361250e
https://doi.org/10.1126/sciadv.ade8500
https://doi.org/10.1126/sciadv.ade8500