Zobrazeno 1 - 10
of 1 175
pro vyhledávání: '"Kai, Shen"'
Autor:
Feng Xiong, Kai Shen, Di Long, Suqing Zhou, Pinglang Ruan, Yue Xin, Yuezheng Xiao, Weijun Peng, Ming Yang, Haijing Wu, Qianjin Lu
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-14 (2024)
Abstract Systemic lupus erythematosus (SLE) is an autoimmune disorder that commonly affects the skin, kidneys, joints, and various other systemic tissues, with its development intricately linked to the process of immunosenescence. Quercetin (QC), a p
Externí odkaz:
https://doaj.org/article/aea139b397014f45a28f2a66cb4a2556
Autor:
Yaru Yang, Hongyan Qiu, Yuru Fan, Qin Zhang, Huiling Qin, Juan Wu, Xuan Zhang, Yueyue Liu, Renpeng Zhou, Qian Zhang, Zi Ye, Jingyue Ma, Ye Xu, Sheng Feng, Yue Fei, Na Li, Xiaojing Cui, Fangli Dong, Quanren Wang, Kai Shen, Sepehr Shakib, Jasmine Williams, Wei Hu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background SHR-1707 is a novel humanized anti-Aβ IgG1 monoclonal antibody that binds to Aβ fibrils and monomers to block the formation of Aβ plaques or to promote the microglial phagocytosis of Aβ. Preclinical studies showed that SHR-170
Externí odkaz:
https://doaj.org/article/c235061a1161431ba736e7493e4d3bee
Publikováno v:
Defence Technology, Vol 38, Iss , Pp 155-170 (2024)
In the process of launching guided projectile under the conventional system, it is difficult to effectively obtain the precise navigation parameters of the projectile in the high dynamic environment. Aiming at this problem, this paper describes a new
Externí odkaz:
https://doaj.org/article/b50f09c9f85b471186e1279a79a6d56c
Autor:
Kang‐Zhen Zhang, Jia‐Wen Li, Jin‐Shui Xu, Zheng‐Kai Shen, Yu‐Shuang Lin, Can Zhao, Xiang Lu, Yun‐Feng Rui, Wei Gao
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 4, Pp 1601-1615 (2024)
Abstract Backgrounds Fat infiltration of skeletal muscle has been recognized as a common feature of many degenerative muscle disorders. Retinol binding protein 4 (RBP4) is an adipokine that has been demonstrated to be correlated with the presence and
Externí odkaz:
https://doaj.org/article/7d43235d769e4c728e4cc76779a02d55
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 7, Pp 1238-1251 (2024)
Abstract Adebrelimab, a novel anti‐PD‐L1 antibody, has been approved by the National Medical Products Administration of China as an intravenous infusion for use in combination with carboplatin and etoposide as first‐line treatment for extensive
Externí odkaz:
https://doaj.org/article/7d2626eea34a4ba0b241e66ef4fbc885
Autor:
Shan-Shan Huang, Yi Ding, Xiao-Na Yi, Hai-Yan Mao, Zhen-Ye Xie, Xing-Kai Shen, Yan Lu, Jing Yan, You-Wei Wang, Zhou-Xin Yang
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-9 (2024)
Abstract Background Bilirubin is known for its multifaceted attributes, including antioxidant, anti-inflammatory, immunomodulatory, and antiapoptotic properties. The systemic immune-inflammation index (SII) is a recent marker that reflects the balanc
Externí odkaz:
https://doaj.org/article/750aa455dcff4360af45d987e1366f0c
Publikováno v:
Journal of Traditional and Complementary Medicine, Vol 14, Iss 4, Pp 467-476 (2024)
STRP1, a polysaccharide active ingredient isolated from the traditional Chinese medicine Sophorae tonkinensis radix, has demonstrated a protective effect against acetaminophen (APAP)-induced liver injury (AILI). The underlying molecular mechanism was
Externí odkaz:
https://doaj.org/article/f6f96ab7b9a1410fb171e5323c7dffde
Autor:
Jia‐Wen Li, Zheng‐Kai Shen, Yu‐Shuang Lin, Zhi‐Yue Wang, Mei‐Lin Li, Hui‐Xian Sun, Quan Wang, Can Zhao, Jin‐Shui Xu, Xiang Lu, Wei Gao
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 3, Pp 1209-1217 (2024)
Abstract Background Sarcopenia is characterized by progressive loss of muscle mass and function due to aging. DNA methylation has been identified to play important roles in the dysfunction of skeletal muscle. The aim of our present study was to explo
Externí odkaz:
https://doaj.org/article/3405a6cd82e746178eca30e198d89dbb
Autor:
Ren-Hui Xiong, Shuo-Qi Yang, Ji-Wei Li, Xun-kai Shen, Lu-Ming Jin, Chao-Yang Chen, Yu-Ting Yue, Zhi-Chen Yu, Qing-Yu Sun, Wen Jiang, Ming-Zheng Jiang, Xiao-Yan Wang, Shi-Xu Song, Dai Cao, Hong-li Ye, Li-Ran Zhao, Li-Peng Huang, Liang Bu
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Background Abnormal expression of protein tyrosine kinase 6 (PTK6) has been proven to be involved in the development of gynecological tumors. However, its immune-related carcinogenic mechanism in other tumors remains unclear. Objective The a
Externí odkaz:
https://doaj.org/article/ec100f6beb184953a14676866b008603
Autor:
Charlie Tran, Kai Shen, Kang Liu, Akshay Ashok, Adolfo Ramirez-Zamora, Jinghua Chen, Yulin Li, Ruogu Fang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Parkinson’s disease is the world’s fastest-growing neurological disorder. Research to elucidate the mechanisms of Parkinson’s disease and automate diagnostics would greatly improve the treatment of patients with Parkinson’s disease.
Externí odkaz:
https://doaj.org/article/091c6ce186b142a18ce62c18956817de