Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Kai, Schuh"'
Autor:
Monique Jänsch, Lubomir T. Lubomirov, Maximilian Trum, Tatjana Williams, Joachim Schmitt, Kai Schuh, Fatimunnisa Qadri, Lars S. Maier, Michael Bader, Oliver Ritter
Publikováno v:
FEBS Open Bio, Vol 13, Iss 1, Pp 118-132 (2023)
Recent evidence demonstrated that alterations in the QT interval duration on the ECG are not only determined by mutations in genes for ion channels, but also by modulators of ion channels. Changes in the QT interval duration beyond certain thresholds
Externí odkaz:
https://doaj.org/article/8069512204c84c57aff6a458cf969748
Autor:
Franziska Werner, Estefania Prentki Santos, Konstanze Michel, Hanna Schrader, Katharina Völker, Tamara Potapenko, Lisa Krebes, Marco Abeßer, Dorothe Möllmann, Martin Schlattjan, Hannes Schmidt, Boris V. Skryabin, Katarina Špiranec Spes, Kai Schuh, Christopher P. Denton, Hideo A. Baba, Michaela Kuhn
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
Excessive activation of cardiac fibroblasts (CFs) in response to injury provokes cardiac fibrosis, stiffness, and failure. The local mediators counterregulating this response remain unclear. Exogenous C-type natriuretic peptide (CNP) exerts antifibro
Externí odkaz:
https://doaj.org/article/7283f518feaf421cb1374fda596e995c
Autor:
Konstanze Michel, Melissa Herwig, Franziska Werner, Katarina Špiranec Spes, Marco Abeßer, Kai Schuh, Swati Dabral, Andreas Mügge, Hideo A. Baba, Boris V. Skryabin, Nazha Hamdani, Michaela Kuhn
Publikováno v:
JCI Insight, Vol 5, Iss 22 (2020)
Heart failure is often accompanied by titin-dependent myocardial stiffness. Phosphorylation of titin by cGMP-dependent protein kinase I (PKGI) increases cardiomyocyte distensibility. The upstream pathways stimulating PKGI-mediated titin phosphorylati
Externí odkaz:
https://doaj.org/article/bc488a37aaa24a19ac2437a35f753e5f
Autor:
Denis Hepbasli, Sina Gredy, Melanie Ullrich, Amelie Reigl, Marco Abeßer, Thomas Raabe, Kai Schuh
Publikováno v:
Brain Sciences, Vol 11, Iss 10, p 1365 (2021)
Vocalization is an important part of social communication, not only for humans but also for mice. Here, we show in a mouse model that functional deficiency of Sprouty-related EVH1 domain-containing 2 (SPRED2), a protein ubiquitously expressed in the
Externí odkaz:
https://doaj.org/article/61961403a09145818af2c4c1b4cfc5f3
Publikováno v:
Physiology. 38
Dysfunction of autophagy has been associated with cardiac arrhythmias and cardiomyopathies, mainly because failure of the system leads to intracellular depositions. One important signaling cascade controlling myocardial cell homeostasis and important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13a2c03284c4106daeb3e25951a6b282
https://doi.org/10.1152/physiol.2023.38.s1.5731035
https://doi.org/10.1152/physiol.2023.38.s1.5731035
Autor:
Lea Ulrich, Carla Gliem, Dieter Groneberg, Timo Frömel, Kai Schuh, Ingrid Fleming, Peter M. Benz
Enabled/vasodilator stimulated phosphoproteins (Ena/VASP) proteins are important regulators of the cytoskeleton, linking kinase signaling pathways to actin assembly. In mammals, the Ena/VASP family of proteins consists of mammalian enabled (Mena), VA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03683627772e31b2eb0a87004f16458d
https://doi.org/10.1101/2023.04.21.537622
https://doi.org/10.1101/2023.04.21.537622
Autor:
Leticia Prates Roma, Anna-Florentine Schiuma, Kai Schuh, Martin van der Laan, Jan Dudek, Julia Schwemmlein, Sarah Atighetchi, Michael Böhm, Edoardo Bertero, Christopher Carlein, Andreas Müller, Carolin Brune, Peter Rehling, Markus Hoth, Andrey Kazakov, Michaela Kuhn, Mathias Hohl, Christoph Maack, Ulrich Laufs, Michael Kohlhaas, Vasco Sequeira, Ilona Kutschka, Marco Abeßer, Kai Münker, Alexander Nickel, Reinhard Kappl, Karina von der Malsburg, Alexander von der Malsburg
Publikováno v:
Circulation. 144:1694-1713
Background: Barth syndrome (BTHS) is caused by mutations of the gene encoding tafazzin, which catalyzes maturation of mitochondrial cardiolipin and often manifests with systolic dysfunction during early infancy. Beyond the first months of life, BTHS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dc7d7ca51902412ab37f2eea26fcb04
https://doi.org/10.1161/circulationaha.121.053755
https://doi.org/10.1161/circulationaha.121.053755
Autor:
Monique Jänsch, Lubomir T. Lubomirov, Maximilian Trum, Tatjana Williams, Joachim Schmitt, Kai Schuh, Fatimunnisa Qadri, Lars S. Maier, Michael Bader, Oliver Ritter
Publikováno v:
FEBS open bioReferences.
Recent evidence demonstrated that alterations in the QT interval duration on the ECG are not only determined by mutations in genes for ion channels, but also by modulators of ion channels. Changes in the QT interval duration beyond certain thresholds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc33c99a311f76ece4ce30a060c89961
https://pubmed.ncbi.nlm.nih.gov/36352324
https://pubmed.ncbi.nlm.nih.gov/36352324
Autor:
Marco Abeßer, Frank Schweda, Petra Eder Negrin, Katharina Völker, Kai Schuh, Antonella Cellini, Lisa Krebes, Viacheslav O. Nikolaev, Franz Hofmann, Alexander Nickel, Katarina Špiranec Spes, Michaela Kuhn, Wen Chen
Publikováno v:
Hypertension. 76:1637-1648
Cardiac ANP (atrial natriuretic peptide) moderates arterial blood pressure. The mechanisms mediating its hypotensive effects are complex and involve inhibition of the renin-angiotensin-aldosterone system, increased natriuresis, endothelial permeabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1dc8397e8bd1859babc9698f11b84c
https://doi.org/10.1161/hypertensionaha.120.15772
https://doi.org/10.1161/hypertensionaha.120.15772
Autor:
Edoardo, Bertero, Alexander, Nickel, Michael, Kohlhaas, Mathias, Hohl, Vasco, Sequeira, Carolin, Brune, Julia, Schwemmlein, Marco, Abeßer, Kai, Schuh, Ilona, Kutschka, Christopher, Carlein, Kai, Münker, Sarah, Atighetchi, Andreas, Müller, Andrey, Kazakov, Reinhard, Kappl, Karina, von der Malsburg, Martin, van der Laan, Anna-Florentine, Schiuma, Michael, Böhm, Ulrich, Laufs, Markus, Hoth, Peter, Rehling, Michaela, Kuhn, Jan, Dudek, Alexander, von der Malsburg, Leticia, Prates Roma, Christoph, Maack
Publikováno v:
Circulation. 144(21)
Barth syndrome (BTHS) is caused by mutations of the gene encoding tafazzin, which catalyzes maturation of mitochondrial cardiolipin and often manifests with systolic dysfunction during early infancy. Beyond the first months of life, BTHS cardiomyopat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcf43f159d12506e4114c3628bb70e29
https://pubmed.ncbi.nlm.nih.gov/34648376
https://pubmed.ncbi.nlm.nih.gov/34648376