Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kahuku Oades"'
Autor:
Ali Cullors, Kahuku Oades, Jorge A. Garces, Elaine A. Sugarman, Joel Centeno, David Taylor, Juan-Sebastian Saldivar
Publikováno v:
Pharmacogenomics and Personalized Medicine
The health care costs associated with prescription drugs are enormous, particularly in patients with polypharmacy (taking more than five prescription medications), and they continue to grow annually. The evolution of pharmacogenetics has provided cli
Autor:
Young K. Song, Maria Pickering, Jun S. Wei, Gordon Vansant, Joseph Monforte, Kahuku Oades, Javed Khan, Qing-Rong Chen
Publikováno v:
The Journal of Molecular Diagnostics. 9:80-88
The small round blue cell tumors of childhood, which include neuroblastoma, rhabdomyosarcoma, non-Hodgkin’s lymphoma, and the Ewing’s family of tumors, are so called because of their similar appearance on routine histology. Using cDNA microarray
Autor:
Julie Kerby, Gopalan V. Pillai, Paul J. Whiting, Timothy P. Bonnert, Ruth M. McKernan, Kahuku Oades, Peter B. Simpson, Charles E. Adkins, Christine Haldon, Jesus E. Gonzalez
Publikováno v:
The Journal of biological chemistry. 276(42)
Selective modulators of gamma-aminobutyric acid, type A (GABA(A)) receptors containing alpha(4) subunits may provide new treatments for epilepsy and premenstrual syndrome. Using mouse L(-tk) cells, we stably expressed the native GABA(A) receptor subu
Publikováno v:
Drug discovery today. 4(9)
Ion channels are an important class of drug targets. They comprise the molecular basis for essential physiological functions including fluid secretion, electrolyte balance, bioenergetics and membrane excitability. High-throughput screening for ion-ch
Autor:
Gordon Vansant, Kahuku Oades, Byung-In Lee, Joseph Monforte, Lien Vo, Rhonda Meredith, Hyun-Soo Kim, Mark Landers, Jerry Lee
Publikováno v:
Journal of Clinical Oncology. 31:11108-11108
11108 Background: Gene expression signatures have become a useful tool for the identification of tumor subtypes and response to specific therapies. Expression of tumor, metastatic and macrophage specific transcripts utilizing alternative promoters an
Publikováno v:
Cancer Research. 73:4143-4143
Background: Gene expression profiling has been shown to be effective in the analysis of postoperative tumor samples in various cancers. However, for studies requiring the analysis of small specimens, such as core biopsies, the limited amount of avail
Publikováno v:
Journal of Clinical Oncology. 30:56-56
56 Background: Gene expression profiling has been shown to be effective in analyzing postoperative tumor samples in various cancers. However, in analyzing small specimens such as core biopsies, the limited amount of available material makes multi-gen
Autor:
Sean Eddy, Lien Vo, Joseph Monforte, Mark Tomilo, Peter Wyngaard, Yipeng Wang, Paul J. Williams, Hyun-Chul Kim, Daniel R. Rhodes, Byung-In Lee, Seth Sadis, Kahuku Oades
Publikováno v:
Journal of Clinical Oncology. 30:e14164-e14164
e14164 Background: While KRAS mutation predicts resistance to anti-EGFR therapy in colorectal cancer, not all KRAS wild-type patients benefit from such therapy, suggesting that complementary biomarkers capable of identifying additional non-responsive
Autor:
Teresa Macarulla, Paul J. Williams, Josep Tabernero, Lien Vo, Mark Tomilo, Joseph Monforte, Sean Eddy, Peter Wyngaard, Byung-In Lee, Kahuku Oades, Yipeng Wang, Seth Sadis, Daniel R. Rhodes, Hyunsoo Kim
Publikováno v:
Clinical Cancer Research. 18:A19-A19
Gene expression modules derived from an unsupervised analysis of 20 independent microarray datasets comprising more than 2,000 colorectal cancer patients were identified. Each module represents a set of highly co-expressed genes related to an importa
Autor:
Paul Williams, Lien Vo, Joseph Monforte, Peter Wyngaard, Dafydd G. Thomas, Seth Sadis, Kahuku Oades, Byung-In Lee, Scott A. Tomlins, Yipeng Wang, Daniel R. Rhodes, S. Chattopadhyay
Publikováno v:
Cancer Research. 72:3664-3664
Gene expression profiles of human breast tumors have greatly expanded our understanding of the genes and pathways that underlie breast cancer. Profiling studies have also supported a molecular classification of breast cancer. The resulting molecular