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pro vyhledávání: '"Kahrilas, P J"'
Autor:
Elisha, Guy, Halder, Sourav, Liu, Xinyi, Carlson, Dustin A., Kahrilas, Peter J., Pandolfino, John E., Patankar, Neelesh A.
An understanding how neurological disorders lead to mechanical dysfunction of the esophagus requires knowledge of the neural circuit of the enteric nervous system. Historically, this has been elusive. Here, we present an empirically guided neural cir
Externí odkaz:
http://arxiv.org/abs/2402.18103
Autor:
Elisha, Guy, Gast, Richard, Halder, Sourav, Solla, Sara A., Kahrilas, Peter J., Pandolfino, John E., Patankar, Neelesh A.
Certain biological systems exhibit both direct and retrograde propagating wave signals, despite unidirectional neural coupling. However, there is no model to explain this. Therefore, the underlying physics of reversing the signal's direction for one-
Externí odkaz:
http://arxiv.org/abs/2402.18100
Autor:
Elisha, Guy, Halder, Sourav, Carlson, Dustin A., Kou, Wenjun, Kahrilas, Peter J., Pandolfino, John E., Patankar, Neelesh A.
Functional luminal imaging probe (FLIP) is used to measure cross-sectional area (CSA) and pressure at sphincters. It consists of a catheter surrounded by a fluid filled cylindrical bag, closed on both ends. Plotting the pressure-CSA hysteresis of a s
Externí odkaz:
http://arxiv.org/abs/2209.08419
Autor:
Halder, Sourav, Johnson, Ethan M., Yamasaki, Jun, Kahrilas, Peter J., Markl, Michael, Pandolfino, John E., Patankar, Neelesh A.
Publikováno v:
Frontiers in Physiology. 14 (2023)
Dynamic magnetic resonance imaging (MRI) is a popular medical imaging technique to generate image sequences of the flow of a contrast material inside tissues and organs. However, its application to imaging bolus movement through the esophagus has onl
Externí odkaz:
http://arxiv.org/abs/2209.07492
Autor:
Elisha, Guy, Halder, Sourav, Acharya, Shashank, Carlson, Dustin A., Kou, Wenjun, Kahrilas, Peter J., Pandolfino, John E., Patankar, Neelesh A.
The esophagogastric junction (EGJ) is located at the distal end of the esophagus and acts as a valve allowing swallowed materials to enter the stomach and preventing acid reflux. Irregular weakening or stiffening of the EGJ muscles result in changes
Externí odkaz:
http://arxiv.org/abs/2201.01355
Autor:
Elisha, Guy, Acharya, Shashank, Halder, Sourav, Carlson, Dustin A., Kou, Wenjun, Kahrilas, Peter J., Pandolfino, John E., Patankar, Neelesh A.
A FLIP device gives cross-sectional area along the length of the esophagus and one pressure measurement, both as a function of time. Deducing mechanical properties of the esophagus including wall material properties, contraction strength, and wall re
Externí odkaz:
http://arxiv.org/abs/2112.14858
Autor:
Halder, Sourav, Yamasaki, Jun, Acharya, Shashank, Kou, Wenjun, Elisha, Guy, Carlson, Dustin A., Kahrilas, Peter J., Pandolfino, John E., Patankar, Neelesh A.
Publikováno v:
Artificial Intelligence in Medicine. 134 (2022) 102435
The pathogenesis of esophageal disorders is related to the esophageal wall mechanics. Therefore, to understand the underlying fundamental mechanisms behind various esophageal disorders, it is crucial to map the esophageal wall mechanics-based paramet
Externí odkaz:
http://arxiv.org/abs/2111.09993
Autor:
Acharya, Shashank, Halder, Sourav, Kou, Wenjun, Kahrilas, Peter J., Pandolfino, John E., Patankar, Neelesh A.
Over the past few decades, in silico modeling of organ systems has significantly furthered our understanding of their physiology and biomechanical function. In this work, we present a detailed numerical model of the upper gastrointestinal (GI) tract
Externí odkaz:
http://arxiv.org/abs/2103.14814
Autor:
Halder, Sourav, Acharya, Shashank, Kou, Wenjun, Kahrilas, Peter J., Pandolfino, John E., Patankar, Neelesh A.
Publikováno v:
Biomechanics and Modeling in Mechanobiology. 20 (2021) 925-940
Fluoroscopy is a radiographic procedure for evaluating esophageal disorders such as achalasia, dysphasia and gastroesophageal reflux disease (GERD). It performs dynamic imaging of the swallowing process and provides anatomical detail and a qualitativ
Externí odkaz:
http://arxiv.org/abs/2008.11102
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