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pro vyhledávání: '"Kahori Sasahara"'
Autor:
Takashi Shimamoto, Kahori Sasahara, Nobuaki Matsubara, Yoichi Naito, Naoyoshi Yatsuzuka, Noboru Yamamoto, Izumi Ohno, Toshio Shimizu, Yutaka Fujiwara, Kan Yonemori, Lance Leopold, Toshihiko Doi, Tomoko Takami, Kohei Shitara, Takahiro Kogawa
Publikováno v:
Molecular Cancer Therapeutics. 17:A204-A204
Background: INCB024360 (epacadostat) is an oral, potent, selective inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), a tryptophan-catabolizing enzyme that induces immune tolerance by T-cell suppression. Preliminary results from the phase I study of