Bi-Functional Chicken Immunoglobulin-Like Receptors With a Single Extracellular Domain (ChIR-AB1): Potential Framework Genes Among a Relatively Stable Number of Genes Per Haplotype

Autor: El Kahina Meziane, Nicola D. Potts, Birgit C. Viertlboeck, Hanne Løvlie, Andrew P. Krupa, Terry A. Burke, Stewart Brown, Kellie A. Watson, David S. Richardson, Tommaso Pizzari, Thomas W. Göbel, Jim Kaufman

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

The leukocyte receptor complex (LRC) in humans encodes many receptors with immunoglobulin-like (Ig-like) extracellular domains, including the killer Ig-like receptors (KIRs) expressed on natural killer (NK) cells among others, the leukocyte Ig-like r

Externí odkaz: https://doaj.org/article/8c5cea1db9244be98466e26205d12178

Expression of Fbxo7 in haematopoietic progenitor cells cooperates with p53 loss to promote lymphomagenesis.

Autor: Mikhail Lomonosov, El Kahina Meziane, Hongtao Ye, David E Nelson, Suzanne J Randle, Heike Laman

Publikováno v: PLoS ONE, Vol 6, Iss 6, p e21165 (2011)

Fbxo7 is an unusual F box protein that augments D-type cyclin complex formation with Cdk6, but not Cdk4 or Cdk2, and its over-expression has been demonstrated to transform immortalised fibroblasts in a Cdk6-dependent manner. Here we present new evide

Externí odkaz: https://doaj.org/article/153ac863f59348c4b49bbdc5327612de

Highly-sensitive quantitative thermal microscopy using gold nano-particles as heat sources

Autor: Kahina Meziane, Antoine Federici, Hadrien M. L. Robert, Serge Monneret, Benoit Wattellier, Guillaume Baffou

Publikováno v: Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVI
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVI, Jan 2018, San Francisco, France. ⟨10.1117/12.2290083⟩

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9863df78c86cefed738c4f7cb8f1c35e
https://hal.archives-ouvertes.fr/hal-01875435

Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding

Autor: James C. Kaufman, C. Butter, Charlotte Durant, Clemens Hermann, Susan M. Lea, Paul E. Chappell, Laura Mears, Alejandro Madrigal, Pietro Roversi, William Mwangi, Łukasz Magiera, Venugopal Nair, A.G. Wrobel, El Kahina Meziane, Michael Harrison, Nicola Ternette, Søren Buus, Trudy Ahyee, Lise Lotte Nielsen, Richard Duggleby

Publikováno v: eLife
Chappell, P E, Meziane, E K, Harrison, M, Magiera, Ł, Hermann, C, Mears, L, Wrobel, A G, Durant, C, Nielsen, L L, Buus, S, Ternette, N, Mwangi, W, Butter, C, Nair, V, Ahyee, T, Duggleby, R, Madrigal, A, Roversi, P, Lea, S M & Kaufman, J 2015, ' Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding ', eLIFE, vol. 4, e05345 . https://doi.org/10.7554/eLife.05345
'eLife ', vol: 4, pages: e05345-1-e05345-22 (2015)
eLife, Vol 4 (2015)

Highly polymorphic major histocompatibility complex (MHC) molecules are at the heart of adaptive immune responses, playing crucial roles in many kinds of disease and in vaccination. We report that breadth of peptide presentation and level of cell sur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f2c8367cbb789814503b0acf5cc922
https://www.repository.cam.ac.uk/handle/1810/248451

Knockdown of Fbxo7 reveals its regulatory role in proliferation and differentiation of haematopoietic precursor cells

Autor: Mikhail Lomonosov, Suzanne J. Randle, Heike Laman, El Kahina Meziane, David E. Nelson

Publikováno v: Journal of cell science. 124(Pt 13)

Fbxo7 is an unusual F-box protein because most of its interacting proteins are not substrates for ubiquitin-mediated degradation. Fbxo7 directly binds p27 and Cdk6, enhances the level of cyclin D–Cdk6 complexes, and its overexpression causes Cdk6-d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d417d63c9bd95cd2e932b1048acc0826
https://pubmed.ncbi.nlm.nih.gov/21652635