A common polymorphism in the Intelectin-1 gene influences mucus plugging in severe asthma

Autor: Jamie L. Everman, Satria P. Sajuthi, Maude A. Liegeois, Nathan D. Jackson, Erik H. Collet, Michael C. Peters, Maurizio Chioccioli, Camille M. Moore, Bhavika B. Patel, Nathan Dyjack, Roger Powell, Cydney Rios, Michael T. Montgomery, Celeste Eng, Jennifer R. Elhawary, Angel C. Y. Mak, Donglei Hu, Scott Huntsman, Sandra Salazar, Luigi Feriani, Ana Fairbanks-Mahnke, Gianna L. Zinnen, Cole R. Michel, Joe Gomez, Xing Zhang, Vivian Medina, Hong Wei Chu, Pietro Cicuta, Erin D. Gordon, Pamela Zeitlin, Victor E. Ortega, Nichole Reisdorph, Eleanor M. Dunican, Monica Tang, Brett M. Elicker, Travis S. Henry, Eugene R. Bleecker, Mario Castro, Serpil C. Erzurum, Elliot Israel, Bruce D. Levy, David T. Mauger, Deborah A. Meyers, Kaharu Sumino, David S. Gierada, Annette T. Hastie, Wendy C. Moore, Loren C. Denlinger, Nizar N. Jarjour, Mark L. Schiebler, Sally E. Wenzel, Prescott G. Woodruff, Jose Rodriguez-Santana, Chad G. Pearson, Esteban G. Burchard, John V. Fahy, Max A. Seibold

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)

Abstract By incompletely understood mechanisms, type 2 (T2) inflammation present in the airways of severe asthmatics drives the formation of pathologic mucus which leads to airway mucus plugging. Here we investigate the molecular role and clinical si

Externí odkaz: https://doaj.org/article/e5fbd453726447a6a3e42371a05beeb5

Stakeholder engagement in eight comparative effectiveness trials in African Americans and Latinos with asthma

Autor: Tiffany Dy, Winifred J. Hamilton, C. Bradley Kramer, Andrea Apter, Jerry A. Krishnan, James W. Stout, Stephen J. Teach, Alex Federman, John Elder, Tyra Bryant-Stephens, Rebecca J. Bruhl, Shawni Jackson, Kaharu Sumino

Publikováno v: Research Involvement and Engagement, Vol 8, Iss 1, Pp 1-16 (2022)

Plain English summary The goal of comparative clinical effectiveness research is to compare healthcare options and learn which work best for patients depending on their preferences and circumstances. Research efforts can be more effective when resear

Externí odkaz: https://doaj.org/article/078bf61bee244673802bd26529fb23a5

A Call for the United States to Accelerate the Implementation of Reliever Combination Inhaled Corticosteroid–Formoterol Inhalers in Asthma

Autor: James G. Krings, Joe K. Gerald, Kathryn V. Blake, Jerry A. Krishnan, Helen K. Reddel, Leonard B. Bacharier, Anne E. Dixon, Kaharu Sumino, Lynn B. Gerald, Ross C. Brownson, Stephen D. Persell, Conrad J. Clemens, Katherine M. Hiller, Mario Castro, Fernando D. Martinez

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 207:390-405

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5fc593249e1a4f98dc2c45d5a7bb3c8c
https://doi.org/10.1164/rccm.202209-1729pp

Beginning to address an implementation gap in asthma: clinicians’ views of prescribing reliever ICS-formoterol inhalers and SMART in the United States

Autor: James G. Krings, Tejas C. Sekhar, Vanessa Chen, Kathryn V. Blake, Kaharu Sumino, Aimee S. James, Amber K. Clover, Eric J. Lenze, Ross C. Brownson, Mario Castro

Publikováno v: The Journal of Allergy and Clinical Immunology: In Practice.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a3c2c22a50e5b1264555c18171697bf
https://doi.org/10.1016/j.jaip.2023.05.023

Severe Asthma Standard-of-Care Background Medication Reduction With Benralizumab: ANDHI in Practice Substudy

Autor: Renaud Louis, Tim W. Harrison, Pascal Chanez, Francesco Menzella, George Philteos, Borja G. Cosio, Njira L. Lugogo, Gustavo de Luiz, Annie Burden, Timothy Adlington, Nanna Keeling, Justin Kwiatek, Esther Garcia Gil, Wolfgang Pohl, Daniel Doberer, Jean Benoit Martinot, Maud Deschampheleire, Ulrike Himpe, Kenneth Chapman, Amarjit Cheema, Delbert Dorscheid, Clare Ramsey, Jeffrey Rolf, Brandie Walker, Ronald Olivenstein, Claude Poirier, Pierre Larivee, Anne Sofie Bjerrum, Ingrid Titlestad, Ole Hilberg, Maritta Kilpeläinen, Philippe Bonniaud, Camille Taillé, Iuliana-Angelica Tiotiu, Pierre-Olivier Girodet, François-Xavier Blanc, Johana Pradelli, Alain Didier, Cecilia Nocent Ejnaini, Gaetan Deslee, Christophe Pison, Youcef Douadi, Guillaume Mahay, Gilles Devouassoux, Boris Melloni, Pauline-Marie Roux, Arnaud Bourdin, Stephanie Fry, Thomas Schaum, Christian Schulz, Dirk Skowasch, Christian Taube, Tobias Welte, Wolfgang Gleiber, Randolf Brehler, Jens Schreiber, Wolfgang Schuette, Juliane Kronsbein, Reiner Bonnet, Ekkehard Beck, Donato Lacedonia, Gianenrico Senna, Cristiano Caruso, Nunzio Crimi, Francesco Blasi, Pierachille Santus, Giorgio Walter Canonica, Gabriella Guarnieri, Girolamo Pelaia, Manlio Milanese, Claudio Micheletto, Angelo Guido Corsico, Nicola Scichilone, Giuseppe Spadaro, Bas Langeveld, Jurgen Holters, Jan Willem van den Berg, Arthur Smit, Lennart Conemans, Helena van Veen, Gerald Staaks, Sverre Lehmann, Jose Maria Echave-Sustaeta, Christian Domingo Ribas, Gustavo de Luiz Martinez, Ruperto Gonzalez Perez, Juan Luis Garcia Rivero, Xavier Muñoz Gall, Jose Gregorio Soto Campos, Paloma Campo Mozo, Carmen Vidal Pan, Ana Gomez-Bastero Fernandez, Sergio Campos Tellez, Carlos Martinez Rivera, Irina Diana Bobolea, Raquel Morillo Guerrero, Ismael Ali Garcia, Juan Luis Rodriguez Hermosa, Nikolai Stenfors, Alf Tunsäter, Dan Curiac, Christophe von Garnier, Joerg Leuppi, Peter Schmid-Grendelmeier, Shuaib Nasser, Rekha Chaudhuri, Monica Nordstrom, Dinesh Saralaya, Paul Pfeffer, Adel Mansur, Philip Short, Sally Wenzel, William Brett Cherry, Heidi Zafra, Erika Gonzalez, Weily Soong, Benjamin Davis, Neil Kao, Iftikhar Hussain, Diego Jose Maselli Caceres, James Harris, William Calhoun, Ileana Rodicio, David Kaufman, Mark Moss, Eric Sztejman, Samuel DeLeon, Kaharu Sumino, Ravindra Kashyap, Jeffrey Leflein, Rizan Hajal, Faisal Fakih, David Hill, Robert Lin, Mikell Jarratt, Vijay Subramaniam, Robert Sussman, Nayla Mumneh, Joan Reibman, Jared Darveaux, Ricardo Tan, Tonny Tanus, Vinay Sikand, Gailen Marshall, Hemalini Mehta, Jeremy Cole, Brad Goodman, Deborah Goss, Jose Bardelas, Aaron Milstone, Vinay Mehta, Lee Clore, Mark Millard, Michael Palumbo, Dileep Puppala, Mila Leong, Bruce Prenner, Emory Robinette, Hengameh Heidarian Raissy, David Fost, Warren Pleskow, Michael Marcus, Jonathan Ilowite, Wendy Moore, Gary Steven, Luis De la Cruz, Geoffrey Chupp, William Berger, Christopher Randolph, Fernando Holguin, Shahrukh Kureishy, Edward Campbell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd466bedc769e3fc1175021e7c3165d4
https://hdl.handle.net/11379/578845