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A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control.

Autor: Wang Y; Department of Immunology, Harvard Medical School, Boston, MA, USA., Zhang Y; Department of Immunology, Harvard Medical School, Boston, MA, USA., Kim K; Center for Bacterial Pathogenesis and Department of Microbiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Han J; Department of Pathology, Washington University School of Medicine, St. Louis, MO, USA., Okin D; Division of Gastroenterology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Jiang Z; Division of Innate Immunity, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Yang L; Department of Immunology, Harvard Medical School, Boston, MA, USA., Subramaniam A; Immunology and Inflammatory Research Therapeutic Area, Sanofi, Cambridge, MA, USA., Means TK; Immunology and Inflammatory Research Therapeutic Area, Sanofi, Cambridge, MA, USA., Nestlé FO; Immunology and Inflammatory Research Therapeutic Area, Sanofi, Cambridge, MA, USA., Fitzgerald KA; Division of Innate Immunity, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Randolph GJ; Department of Pathology, Washington University School of Medicine, St. Louis, MO, USA., Lesser CF; Center for Bacterial Pathogenesis and Department of Microbiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Kagan JC; Division of Gastroenterology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Mathis D; Department of Immunology, Harvard Medical School, Boston, MA, USA., Benoist C; Department of Immunology, Harvard Medical School, Boston, MA, USA. Electronic address: cbdm@hms.harvard.edu.

Publikováno v: Immunity [Immunity] 2024 Nov 14. Date of Electronic Publication: 2024 Nov 14.