Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kaemena DF"'
Autor:
Aarts, M, Georgilis, A, Beniazza, M, Beolchi, P, Banito, A, Carroll, T, Kulisic, M, Kaemena, DF, Dharmalingam, G, Martin, N, Reik, W, Zuber, J, Kaji, K, Chandra, T, Gil, J
Publikováno v:
Aarts, M, Georgilis, A, Beniazza, M, Beolchi, P, Banito, A, Carroll, T, Kulisic, M, Kaemena, D F, Dharmalingam, G, Martin, N, Reik, W, Zuber, J, Kaji, K, Chandra, T & Gil, J 2017, ' Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence ', Genes and Development, vol. 31, no. 20, pp. 2085-2098 . https://doi.org/10.1101/gad.297796.117
Expression of the transcription factors OCT4, SOX2, KLF4, and cMYC (OSKM) reprograms somatic cells into induced pluripotent stem cells (iPSCs). Reprogramming is a slow and inefficient process, suggesting the presence of safeguarding mechanisms that c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::790ba75eca47c1dd4a981857e98bbfee
https://europepmc.org/articles/PMC5733499/
https://europepmc.org/articles/PMC5733499/
Autor:
Kaemena DF; Centre for Regenerative Medicine, Institute for Regenaration and Repair, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh, Scotland, UK., Yoshihara M; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.; Institute for Advanced Academic Research, Chiba University, Chiba, Japan.; Department of Artificial Intelligence Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan., Beniazza M; Centre for Regenerative Medicine, Institute for Regenaration and Repair, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh, Scotland, UK., Ashmore J; Centre for Regenerative Medicine, Institute for Regenaration and Repair, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh, Scotland, UK., Zhao S; Centre for Regenerative Medicine, Institute for Regenaration and Repair, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh, Scotland, UK., Bertenstam M; Computational Biology and Biological Physics, Lund University, Lund, Sweden., Olariu V; Computational Biology and Biological Physics, Lund University, Lund, Sweden., Katayama S; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.; Research Programs Unit, Stem Cells and Metabolism Research Program (STEMM), University of Helsinki, Helsinki, Finland.; Folkhälsan Research Center, Helsinki, Finland., Okita K; Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan., Tomlinson SR; Centre for Regenerative Medicine, Institute for Regenaration and Repair, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh, Scotland, UK., Yusa K; Stem Cell Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK.; Stem Cell Genetics, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan., Kaji K; Centre for Regenerative Medicine, Institute for Regenaration and Repair, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh, Scotland, UK. keisuke.kaji@ed.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2023 Jan 30; Vol. 14 (1), pp. 488. Date of Electronic Publication: 2023 Jan 30.
Autor:
Ruetz T; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, Scotland, UK., Pfisterer U; Department of Experimental Medical Science, Developmental and Regenerative Neurobiology, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, 22184 Lund, Sweden., Di Stefano B; Centre for Genomic Regulation, Dr Aiguader 88, 08003 Barcelona, Spain; Universitat Pompeu Fabra (UPF), Dr Aiguader 88, 08003 Barcelona, Spain., Ashmore J; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, Scotland, UK., Beniazza M; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, Scotland, UK., Tian TV; Centre for Genomic Regulation, Dr Aiguader 88, 08003 Barcelona, Spain; Universitat Pompeu Fabra (UPF), Dr Aiguader 88, 08003 Barcelona, Spain., Kaemena DF; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, Scotland, UK., Tosti L; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, Scotland, UK., Tan W; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, Scotland, UK., Manning JR; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, Scotland, UK., Chantzoura E; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, Scotland, UK., Ottosson DR; Department of Experimental Medical Science, Developmental and Regenerative Neurobiology, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, 22184 Lund, Sweden., Collombet S; Institut de Biologie de l'Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75005 Paris, France., Johnsson A; Laboratory for Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Scheeles väg 1, SE-171 77 Stockholm, Sweden., Cohen E; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, Scotland, UK., Yusa K; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK., Linnarsson S; Laboratory for Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Scheeles väg 1, SE-171 77 Stockholm, Sweden., Graf T; Centre for Genomic Regulation, Dr Aiguader 88, 08003 Barcelona, Spain; Universitat Pompeu Fabra (UPF), Dr Aiguader 88, 08003 Barcelona, Spain; The Barcelona Institute of Science and Technology, Carrer del Comte d'Urgell 187, Building 12 (BIST), 08036 Barcelona, Spain., Parmar M; Department of Experimental Medical Science, Developmental and Regenerative Neurobiology, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, 22184 Lund, Sweden., Kaji K; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, Scotland, UK. Electronic address: keisuke.kaji@ed.ac.uk.
Publikováno v:
Cell stem cell [Cell Stem Cell] 2017 Dec 07; Vol. 21 (6), pp. 791-805.e9. Date of Electronic Publication: 2017 Nov 22.
Autor:
Aarts M; Medical Research Council (MRC) London Institute of Medical Sciences (LMS), London W12 0NN, United Kingdom.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London W12 0NN, United Kingdom., Georgilis A; Medical Research Council (MRC) London Institute of Medical Sciences (LMS), London W12 0NN, United Kingdom.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London W12 0NN, United Kingdom., Beniazza M; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, United Kingdom., Beolchi P; Medical Research Council (MRC) London Institute of Medical Sciences (LMS), London W12 0NN, United Kingdom.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London W12 0NN, United Kingdom., Banito A; Medical Research Council (MRC) London Institute of Medical Sciences (LMS), London W12 0NN, United Kingdom.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London W12 0NN, United Kingdom., Carroll T; Medical Research Council (MRC) London Institute of Medical Sciences (LMS), London W12 0NN, United Kingdom.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London W12 0NN, United Kingdom., Kulisic M; WaferGen Biosystems, L-1526 Luxembourg, Luxembourg., Kaemena DF; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, United Kingdom., Dharmalingam G; Medical Research Council (MRC) London Institute of Medical Sciences (LMS), London W12 0NN, United Kingdom.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London W12 0NN, United Kingdom., Martin N; Medical Research Council (MRC) London Institute of Medical Sciences (LMS), London W12 0NN, United Kingdom.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London W12 0NN, United Kingdom., Reik W; Epigenetics Programme, The Babraham Institute, Cambridge CB22 3AT, United Kingdom., Zuber J; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna 1030, Austria., Kaji K; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, United Kingdom., Chandra T; Epigenetics Programme, The Babraham Institute, Cambridge CB22 3AT, United Kingdom.; MRC Human Genetics Unit, University of Edinburgh, Edinburgh EH4 2XU, United Kingdom., Gil J; Medical Research Council (MRC) London Institute of Medical Sciences (LMS), London W12 0NN, United Kingdom.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London W12 0NN, United Kingdom.
Publikováno v:
Genes & development [Genes Dev] 2017 Oct 15; Vol. 31 (20), pp. 2085-2098. Date of Electronic Publication: 2017 Nov 14.
Autor:
Tay YD; CRUK Cell Division Group, Paterson Institute for Cancer Research, Wilmslow Road, Manchester M20 4BX, UK., Patel A, Kaemena DF, Hagan IM
Publikováno v:
Journal of cell science [J Cell Sci] 2013 Nov 01; Vol. 126 (Pt 21), pp. 5052-61. Date of Electronic Publication: 2013 Aug 28.