Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kaelan J. Brennan"'
Autor:
Vivekanandan Ramalingam, Xinyang Yu, Brian D. Slaughter, Jay R. Unruh, Kaelan J. Brennan, Anastasiia Onyshchenko, Jeffrey J. Lange, Malini Natarajan, Michael Buck, Julia Zeitlinger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract While the accessibility of enhancers is dynamically regulated during development, promoters tend to be constitutively accessible and poised for activation by paused Pol II. By studying Lola-I, a Drosophila zinc finger transcription factor, w
Externí odkaz:
https://doaj.org/article/2ba41ec6865c4b0da461e51597d9462e
Autor:
Hana Hall, Patrick Medina, Daphne A. Cooper, Spencer E. Escobedo, Jeremiah Rounds, Kaelan J. Brennan, Christopher Vincent, Pedro Miura, Rebecca Doerge, Vikki M. Weake
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-18 (2017)
Abstract Background Aging is associated with functional decline of neurons and increased incidence of both neurodegenerative and ocular disease. Photoreceptor neurons in Drosophila melanogaster provide a powerful model for studying the molecular chan
Externí odkaz:
https://doaj.org/article/4ce92f48e9694b1e8b4132fe5fa8726d
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 8, Pp 2435-2445 (2016)
The Spt-Ada-Gcn5 Acetyltransferase (SAGA) complex is a transcriptional coactivator with histone acetylase and deubiquitinase activities that plays an important role in visual development and function. In Drosophila melanogaster, four SAGA subunits ar
Externí odkaz:
https://doaj.org/article/68ee993e60ba46c4ad7b50f0441f5052
Autor:
Kaelan J. Brennan, Melanie Weilert, Sabrina Krueger, Anusri Pampari, Hsiao-Yun Liu, Ally W.H. Yang, Timothy R. Hughes, Christine A. Rushlow, Anshul Kundaje, Julia Zeitlinger
SummaryChromatin accessibility is integral to the process by which transcription factors (TFs) read out cis-regulatory DNA sequences, but it is difficult to differentiate between TFs that drive accessibility and those that do not. Deep learning model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc16eec0c22767ea551211dde2b59fcc
https://doi.org/10.1101/2022.12.20.520743
https://doi.org/10.1101/2022.12.20.520743
Autor:
Vivekanandan Ramalingam, Xinyang Yu, Brian D. Slaughter, Jay R. Unruh, Kaelan J. Brennan, Anastasiia Onyshchenko, Jeffrey J. Lange, Malini Natarajan, Michael Buck, Julia Zeitlinger
While enhancers are often regulated at the level of accessibility by pioneer factors, promoters tend to be constitutively accessible and poised for activation by paused Pol II — thus are often not considered as sites of developmental regulation. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23f492b3398fb4e71955e4fda365df58
https://doi.org/10.1101/2022.04.25.489272
https://doi.org/10.1101/2022.04.25.489272
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 8, Pp 2435-2445 (2016)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
The Spt-Ada-Gcn5 Acetyltransferase (SAGA) complex is a transcriptional coactivator with histone acetylase and deubiquitinase activities that plays an important role in visual development and function. In Drosophila melanogaster, four SAGA subunits ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639baf35f0a8be11f32144fc1997f7f6
https://doi.org/10.1534/g3.116.031310
https://doi.org/10.1534/g3.116.031310
Autor:
Spencer E. Escobedo, Christopher Vincent, Hana Hall, Kaelan J. Brennan, Patrick S Medina, Vikki M. Weake, Jeremiah Rounds, Rebecca W. Doerge, Pedro Miura, Daphne A. Cooper
Publikováno v:
BMC Genomics
BMC Genomics, Vol 18, Iss 1, Pp 1-18 (2017)
BMC Genomics, Vol 18, Iss 1, Pp 1-18 (2017)
Background Aging is associated with functional decline of neurons and increased incidence of both neurodegenerative and ocular disease. Photoreceptor neurons in Drosophila melanogaster provide a powerful model for studying the molecular changes invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e47e6b8297395dcb3d0ad93df413cb
http://europepmc.org/articles/PMC5698953
http://europepmc.org/articles/PMC5698953