Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kaela Drzewiecki"'
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102480- (2023)
Summary: Liver endothelial cells (LECs) are critical in maintaining liver homeostasis. To understand the mechanistic processes occurring in these cells, high-quality isolation protocols must be in place. Here, we present a protocol for LEC enrichment
Externí odkaz:
https://doaj.org/article/44fb2ef9df9b4b7681b83bf8fff0a655
Autor:
Kaela Drzewiecki, Jennifer Batisti, Elif A. Oral, Pramod K. Mistry, Angela DeLisle, Allen E. Bale, Daniel J. Dykas, Xuchen Zhang, David N. Assis, Dhanpat Jain, Marina Silveira, Silvia Vilarinho, Aaron Hakim
Publikováno v:
Journal of Hepatology. 70:1214-1221
Background & Aims Adult patients suffering from liver disease of unknown cause represent an understudied and underserved population. The use of whole-exome sequencing (WES) for the assessment of a broader spectrum of non-oncological diseases, among a
Autor:
Chowdhury, Shanin, Fried, Kaela Drzewiecki, Iwakiri, Yasuko, Brancale, Joseph, Vilarinho, Sílvia
Publikováno v:
In STAR Protocols 15 September 2023 4(3)
Autor:
Dhanpat Jain, Gülseren Evirgen Şahin, Kaela Drzewiecki, Joseph Brancale, Elif Karakoc-Aydiner, Buket Dalgic, Helen C. Su, Richard P. Lifton, Kadakkal Radhakrishnan, David E. Kleiner, Aysel Ünlüsoy Aksu, Jungmin Choi, Sinan Sari, Silvia Vilarinho, Junhui Zhang, Ahmet Ozen, Michael A. Leney-Greene, Safa Baris, Kasper Hoebe, Michael J. Lenardo, Michael Schmalz, João Pereira
Publikováno v:
The Journal of Experimental Medicine
Genomic analysis of families with unexplained portal hypertension reveals GIMAP5 as a critical regulator of liver sinusoidal endothelial cells and hepatic vascular homeostasis. This study identifies a novel genetic cause of portal hypertension and pr