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Akademický článek

Fabrication of a Gelatin-Based Microdevice for Vascular Cell Culture

Autor: Satoko Sasaki, Tomoko Suzuki, Kyojiro Morikawa, Michiya Matsusaki, Kae Sato

Publikováno v: Micromachines, Vol 14, Iss 1, p 107 (2022)

This study presents a novel technique for fabricating microfluidic devices with microbial transglutaminase-gelatin gels instead of polydimethylsiloxane (PDMS), in which flow culture simulates blood flow and a capillary network is incorporated for ass

Externí odkaz: https://doaj.org/article/45cefb7b58a54a0798ece171ac604fa2

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Akademický článek

Nitric Oxide and a Conditioned Medium Affect the Hematopoietic Development in a Microfluidic Mouse Embryonic Stem Cell/OP9 Co-Cultivation System

Autor: Kae Sato, Momoko Maeda, Eriko Kamata, Sayaka Ishii, Kanako Yanagisawa, Kenji Kitajima, Takahiko Hara

Publikováno v: Micromachines, Vol 11, Iss 3, p 305 (2020)

A microfluidic co-culture system, consisting of mouse embryonic stem cells (mESCs)/OP9 cells, was evaluated as a platform for studying hematopoietic differentiation mechanisms in vitro. mESC differentiation into blood cells was achieved in a microcha

Externí odkaz: https://doaj.org/article/3049869068044b8b9e802262059b021e

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Akademický článek

A Microfluidic Cell Stretch Device to Investigate the Effects of Stretching Stress on Artery Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension

Autor: Kae Sato, Manami Nitta, Aiko Ogawa

Publikováno v: Inventions, Vol 4, Iss 1, p 1 (2018)

A microfluidic cell stretch device was developed to investigate the effects of stretching stress on pulmonary artery smooth muscle cell (PASMC) proliferation in pulmonary arterial hypertension (PAH). The microfluidic device harbors upper cell culture

Externí odkaz: https://doaj.org/article/e10d1f039f24484c873304724abd6df9

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Akademický článek

Effects of Microchannel Shape and Ultrasonic Mixing on Microfluidic Padlock Probe Rolling Circle Amplification (RCA) Reactions

Autor: Yuri Ishigaki, Kae Sato

Publikováno v: Micromachines, Vol 9, Iss 6, p 272 (2018)

The fluorescence in situ hybridization (FISH)-based padlock probe and rolling circle amplification (RCA) method allows for the detection of point mutations. However, it requires multiple reaction steps and solution exchanges, making it costly, labor-

Externí odkaz: https://doaj.org/article/1fd4c5196bd546dbb7c8a03eae7137c6

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Akademický článek

Microcirculation-on-a-Chip: A Microfluidic Platform for Assaying Blood- and Lymphatic-Vessel Permeability.

Autor: Miwa Sato, Naoki Sasaki, Manabu Ato, Satoshi Hirakawa, Kiichi Sato, Kae Sato

Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0137301 (2015)

We developed a microfluidic model of microcirculation containing both blood and lymphatic vessels for examining vascular permeability. The designed microfluidic device harbors upper and lower channels that are partly aligned and are separated by a po

Externí odkaz: https://doaj.org/article/2b49694db1914d0788c649042881188f

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