Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kadri Ligi"'
Autor:
Sergei Kopanchuk, Edijs Vavers, Santa Veiksina, Kadri Ligi, Liga Zvejniece, Maija Dambrova, Ago Rinken
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0268563 (2022)
Sigma-1 receptor (Sig1R) is an endoplasmic reticulum (ER)-related membrane protein, that forms heteromers with other cellular proteins. As the mechanism of action of this chaperone protein remains unclear, the aim of the present study was to detect a
Externí odkaz:
https://doaj.org/article/d7b5711de27e439cbc690a993924147d
Autor:
Kadri Künnapuu, Solomon Ioannou, Kadri Ligi, Raivo Kolde, Sven Laur, Jaak Vilo, Peter R Rijnbeek, Sulev Reisberg
Publikováno v:
JAMIA Open
JAMIA Open, 5(1):ooac021. Oxford University Press
JAMIA Open, 5(1):ooac021. Oxford University Press
Objective To develop a framework for identifying temporal clinical event trajectories from Observational Medical Outcomes Partnership-formatted observational healthcare data. Materials and Methods A 4-step framework based on significant temporal even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2eeeebc0c90354b59d089dbf5c55c7
http://www.scopus.com/inward/record.url?scp=85142041274&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85142041274&partnerID=8YFLogxK
Autor:
Sergei Kopanchuk, Edijs Vavers, Santa Veiksina, Kadri Ligi, Liga Zvejniece, Maija Dambrova, Ago Rinken
Publikováno v:
PloS one. 17(5)
Sigma-1 receptor (Sig1R) is an endoplasmic reticulum (ER)-related membrane protein, that forms heteromers with other cellular proteins. As the mechanism of action of this chaperone protein remains unclear, the aim of the present study was to detect a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744bb85a4bf3261473b8ea238f9442cc
https://pubmed.ncbi.nlm.nih.gov/35584184
https://pubmed.ncbi.nlm.nih.gov/35584184
Autor:
Jaak Vilo, Kadri Künnapuu, Kadri Ligi, Peter R. Rijnbeek, Sulev Reisberg, Sven Laur, Raivo Kolde, Solomon Ioannou
Publikováno v:
medRxiv
ObjectiveTo develop a framework for identifying prominent clinical event trajectories from OMOP-formatted observational healthcare data.MethodsA four-step framework based on significant temporal event pair detection is described and implemented as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fceb0cd9da012966301257109c48b1
Publikováno v:
RSC Advances. 5:96750-96757
A new structural fragment was synthesized for construction of protein binding-responsive photoluminescent probes. In complex with protein kinases of the PIM family, bisubstrate inhibitors containing benzo[4,5]seleno[3,2-d]pyrimidin-4-one moiety revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::695e725a7fda89d1cdb76869fa6ee8d3
https://doi.org/10.1039/c5ra20777k
https://doi.org/10.1039/c5ra20777k
Autor:
Kaido Viht, Erki Enkvist, J. A. Gareth Williams, Lars-Olof Pålsson, Angela Vaasa, Kadri Ligi, Marje Kasari, Asko Uri
Publikováno v:
Biochimica et biophysica acta. 1834(7)
Responsive ARC-Lum probes were used for measurement of the concentration of active protein kinases (PKs) and determination of affinity of inhibitors of PKs. ARC-Lum probes incorporate thiophene or a selenophene heterocycle and a fluorophore conjugate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c640f38d66de03b170711092fc80e19
https://pubmed.ncbi.nlm.nih.gov/23499784
https://pubmed.ncbi.nlm.nih.gov/23499784
Publikováno v:
The Journal of Physical Chemistry B. 120:10421-10421
Cells and bodily fluids possess strong nanosecond-lifetime autofluorescence, therefore photoluminescent probes with microsecond-scale luminescence decay time would be useful for analysis of biological samples, as they allow the performance of measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a6bd3214e2e58ecb0fd003f6501596
https://doi.org/10.1021/acs.jpcb.6b09086
https://doi.org/10.1021/acs.jpcb.6b09086
Publikováno v:
Chemical communications (Cambridge, England). 48(68)
A photoluminescence probe ARC-1185, possessing both high affinity towards basophilic protein kinases (PKs) and microsecond-scale luminescence lifetime when associated with a kinase, was used for the mapping of ARC-1185–PK complexes in living cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb40d03d78e70169b9cd3992571faf6
https://pubmed.ncbi.nlm.nih.gov/22822483
https://pubmed.ncbi.nlm.nih.gov/22822483
Autor:
Asko Uri, Taavi Ivan, Marje Kasari, Gerda Raidaru, Angela Vaasa, Marie Kriisa, Erki Enkvist, Kadri Ligi
Publikováno v:
ACS chemical biology. 6(10)
Time-resolved luminometry-based assays have great potential for measurements in complicated biological solutions and living cells as the measured signal can be easily distinguished from nanosecond lifetime background fluorescence of organic compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fceb9f892c54ee02d5750c90f4993a2
https://pubmed.ncbi.nlm.nih.gov/21776959
https://pubmed.ncbi.nlm.nih.gov/21776959
Publikováno v:
Journal of Physical Chemistry B; Jun2016, Vol. 120 Issue 22, p4945-4954, 10p